Beyond DNA interactions: Insights into idarubicin's binding dynamics with tRNA using spectroscopic and computational approaches [0.03%]
超越DNA相互作用：运用光谱和计算方法研究伊达柔红霉素与tRNA的结合动力学
Sonika Charak,Chandra Mohan Srivastava,Dhruv Kumar et al.
Sonika Charak et al.
Idarubicin (4-demethoxydaunomycin), a structural analogue of daunomycin derived from Streptomyces peucetius, exhibits enhanced anticancer efficacy due to the substitution of a methoxy group with a hydrogen atom. This study investigates the ...
Therapeutic effects of a femtosecond laser on rheumatoid arthritis in rats: Attenuation of oxidative stress and inflammation [0.03%]
飞秒激光对大鼠类风湿性关节炎的治疗作用：减弱氧化应激和炎症反应
Jihad M El-Sayed,Sally M Khadrawy,Aya E Mohamed et al.
Jihad M El-Sayed et al.
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder characterized by joint damage and persistent pain. Despite advances in treatment, there is currently no definitive cure for RA, and the side effects of available medica...
Development and evaluation of nanocomposite vaginal rings for photodynamic therapy against Candida albicans [0.03%]
用于白色念珠菌光动力学治疗的纳米复合阴道环的发展与评估
Sara Efigênia Dantas de Mendonça Y Araújo,Brenda Maria Silva Bezerra,Mariana Rillo Sato et al.
Sara Efigênia Dantas de Mendonça Y Araújo et al.
Antimicrobial photodynamic therapy (aPDT) is based on oxidative photochemical reactions and can be used against vulvovaginal candidiasis (VVC), caused by Candida albicans. This can be achieved by incorporating phthalocyanine (PC) into a pol...
Spectral and color temperature dependence of LED exposure on retinal damage and the protective effects of neohesperidin [0.03%]
LED光照的光谱和色温对视网膜损伤的影响及新榭皮苷的保护作用
Rong Lin,Kunhong Xiao,Boyuan Wen et al.
Rong Lin et al.
Purpose: To investigate the effects of LEDs with different spectra and correlated color temperatures on the retina, as well as the protective role of neohesperidin(NHP). ...
Salvianolic acid B protects against UVB-induced HaCaT cell senescence and skin aging through NRF2 activation and ROS scavenging [0.03%]
丹参酸B通过激活NRF2和清除ROS对UVB诱导的HaCaT细胞衰老及皮肤老化起到保护作用
Jia-Ming Sun,Yu-Xin Liu,Yi-Tung Tsai et al.
Jia-Ming Sun et al.
Background: Prolonged sunlight exposure can cause skin photoaging. The epidermis, the outermost layer of the skin, protects the body from the environment. This study explored the protective effect of salvianolic acid B (S...
Comparative analysis of femtosecond, picosecond, and nanosecond laser techniques for transseptal puncture: An in vitro study with pathological correlation [0.03%]
飞秒、皮秒和纳秒激光技术在房间隔穿刺中的比较分析：具有病理相关性的体外研究
Ang Liu,Tong Xia,Siyuan Cao et al.
Ang Liu et al.
Background: Advanced precision laser technologies for transseptal puncture are still under exploration. Femtosecond lasers, renowned for their high precision and minimal collateral damage, exhibit significant potential in...
Boron dipyrromethene fungicide for anti-microbial photodynamic therapeutics [0.03%]
用于抗微生物光动力治疗的硼双吡咯甲烯类杀菌剂
Aoqing Jia,Min Zheng,Zhigang Xie
Aoqing Jia
Due to inadequate light transmission into the subsurface, one of the key challenges for conventional photodynamic therapy (PDT) is realizing successful treatment of deep-skin pathogenetic bacterial infectious wounds. Preparation of near-inf...
Novel ꞵ-carboline/cyanoisoflavone photosensitizers for ferroptosis-induced efficient chemo-photodynamic synergistic cancer therapy [0.03%]
新型咔唑/氰异黄酮光敏剂用于诱导铁死亡的高效化学光动力协同癌症治疗
Tiantian Sun,Sijia Wang,Xiao Liu et al.
Tiantian Sun et al.
Photodynamic therapy (PDT) is an emerging therapeutic modality to selectively eradicate pathological cells, such as cancer cells. Hence, we designed and synthesized a series of novel ꞵ-carboline/cyanoisoflavone photosensitizers A1-A3. All ...
Construction of a NIR fluorescent probe for tracking mitochondrial HOCl during liver injury [0.03%]
用于追踪肝损伤过程中线粒体HOCl的近红外荧光探针的构建
Cailing Fan,Kaifu Ma,Ran Chen et al.
Cailing Fan et al.
The inappropriate or excessive drug and alcohol consumption is a major cause of liver injuries. The development of a tool capable of visualizing the liver injury process with high precision, and in real time is particularly urgent. In this ...
Photodynamic priming with red light triggers adaptive immune responses in a pancreatic cancer mouse model [0.03%]
红光的光动态预处理触发了胰腺癌小鼠模型中的适应性免疫反应
Pushpamali De Silva,Mohammad A Saad,Joseph W R Swain et al.
Pushpamali De Silva et al.
The poor response of pancreatic ductal adenocarcinoma (PDAC) to treatment, including immunotherapy, is attributed to its tumor microenvironment (TME). An ongoing challenge is the desmoplastic and immunosuppressed TME that evades immune surv...