The institutional roots of vaccine uptake and hesitancy: evidence from Africa [0.03%]
非洲疫苗接种和犹豫不决的制度根源:证据来自非洲
Laura Barasa,Gedion Onyango
Laura Barasa
Africa recorded some of the lowest COVID-19 vaccination rates in the world, with only 32% of the population having completed a primary vaccination series by the end of 2023, despite widespread vaccine availability. Differences in supply and...
Rubella immunity and vaccination coverage among medical students in Catalonia: a multicentre seroprevalence study [0.03%]
加泰罗尼亚医学生患风疹免疫和疫苗接种情况的多中心血清学流行率研究
Pau Benito,Marta Aldea,Pere Godoy et al.
Pau Benito et al.
Background: Rubella is a vaccine-preventable exanthematous viral infection whose most severe complication is congenital rubella syndrome. In countries such as Spain, most medical students are women, a group in which maint...
Qualification of a high-throughput luminescence-based Serum Bactericidal Activity assay to assess the functionality of human sera against five Shigella serotypes [0.03%]
一种高通量发光基血清杀菌活性测定法的鉴定,用于评估五种志贺菌型的人类血清功能
Giuseppe Boccadifuoco,Giulia Fantoni,Federica Verdirosa et al.
Giuseppe Boccadifuoco et al.
Shigellosis is one of the leading causes of diarrhoeal disease worldwide. It mostly affects children under 5 years and elderly persons over 70 years in low- and middle-income countries (LMICs). The high disease incidence in LMICs and the ri...
In-depth monitoring of host cell proteins in influenza vaccines throughout multi-step purification processes [0.03%]
流感疫苗多步骤纯化过程中的宿主细胞蛋白深入监测研究
Bo Liu,Fang Li,Ying Yang et al.
Bo Liu et al.
Influenza viruses, characterized by antigenic drift and shift, can cause seasonal epidemics or pandemics. According to World Health Organization (WHO) data, approximately 650,000 global annual deaths are attributed to influenza-associated r...
Interim analysis of effectiveness of JN.1-adapted conventional and self-amplifying mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infection in adults aged ≥60 years, Japan, October 2024-April 2025 [0.03%]
日本于2024年10月至2025年4月对成人≥60岁人群进行的JN.1适应型常规和自我扩增型mRNA新冠疫苗针对有症状SARS-CoV-2感染有效性的中期分析
Haruka Maeda,Ataru Igarashi,Shinya Mitsui et al.
Haruka Maeda et al.
In Japan, JN.1-adapted conventional mRNA and self-amplifying mRNA (sa-mRNA) COVID-19 vaccines were introduced during the 2024-2025 season. We estimated the effectiveness of these vaccines against symptomatic SARS-CoV-2 infection among adult...
Multi-peptide subunit vaccination induced IFN-γ but lacked efficacy against Mycobacterium avium subsp. paratuberculosis in a goat challenge trial [0.03%]
多肽亚单位疫苗诱导了IFN-γ但缺乏对MAP感染的保护效力
Gitte Erbs,Kari Lybeck,Jeanne Toft Jakobsen et al.
Gitte Erbs et al.
Paratuberculosis is a chronic debilitating disease in ruminants caused by infection with Mycobacterium avium subsp. paratuberculosis (MAP). In endemic herds, animals are infected shortly after birth with no effective control measures beyond...
Characterization of vaccine viremia, attenuation reversion, and safety: Combined results from the TAK-003 dengue vaccine clinical development program [0.03%]
人感染病毒血症、减毒逆转及安全性的特征:登革热疫苗Ⅲ期临床试验的综合结果分析
Vianney Tricou,Xavier Saez-Llorens,Pope Kosalaraksa et al.
Vianney Tricou et al.
Live-attenuated vaccines can replicate for a transient period post-vaccination and may be associated with symptoms resembling natural infection. The tetravalent dengue vaccine, TAK-003, has undergone extensive preclinical assessment to inve...
Maternal respiratory syncytial virus (RSV) vaccine perceptions amongst pregnant women and mothers of infants and toddlers in England: a qualitative study [0.03%]
英国孕期妇女和婴幼儿母亲对母体呼吸道合胞病毒(RSV)疫苗的看法:一项定性研究
Sadie Bell,Tracey Chantler,Alyson Passanante et al.
Sadie Bell et al.
Background: Since September 2024, respiratory syncytial virus (RSV) vaccination has been available in England for pregnant women (from 28 weeks' gestation). ...
Navigating ethical dilemmas during child and adolescent vaccinations: a scoping review [0.03%]
儿童和青少年接种疫苗过程中的伦理困境:一项综述研究
Ashenafi Kibret Sendekie,Leanne Chalmers,Tin Fei Sim et al.
Ashenafi Kibret Sendekie et al.
Background: Vaccination prevents millions of deaths each year; however, ethical dilemmas persist in vaccinating children and adolescents. This scoping review explores how healthcare professionals (HCPs) navigate these eth...
Understanding parent motivation for participating in the Pfizer COVID-19 vaccine trial [0.03%]
理解父母参与辉瑞COVID-19疫苗试验的动机
Myrhiam Diarra,Simon Li,Sunanda Gaur et al.
Myrhiam Diarra et al.
This study aimed to understand parental motivations and concerns regarding enrollment in the Rutgers SARS-CoV-2 (RSC) pediatric vaccine trial during the COVID-19 pandemic. Among the 64 parents who completed the survey, the most commonly rep...