Clinical outcomes of deferred cytoreductive nephrectomy after initial systemic therapy in metastatic renal cell carcinoma: A multicenter retrospective study [0.03%]
一线系统治疗后延迟行肾细胞癌转移性根治性肾切除术的临床结局:多中心回顾性研究
Patricia Rioja,Carolina Passarella,Martín Angel et al.
Patricia Rioja et al.
Introduction: Deferred cytoreductive nephrectomy (dCN) is a selective strategy for managing metastatic renal cell carcinoma (mRCC), in the era of immune checkpoint inhibitors (ICI) and tyrosine kinase inhibitors (TKI), pa...
Hand-sewn versus stapled ileo-ileal anastomosis following radical cystectomy: A systematic review and meta-analysis [0.03%]
根治性膀胱切除术后手工缝合与金属夹吻合的回肠代膀胱效果:系统评价和meta分析
Abdelrahman Abdelshafi,Tarek Mohamed,Hamza Mohamed et al.
Abdelrahman Abdelshafi et al.
Radical cystectomy (RC) with urinary diversion is the standard treatment for muscle-invasive bladder cancer. Intestinal continuity may be restored using either hand-sewn or stapled ileo-ileal anastomosis, yet contemporary evidence comparing...
Presenting postoperative mortality as percentages and natural frequencies (1-in-N) in major urologic cancer surgeries [0.03%]
术后死亡率的表达方式(百分比与自然频率)——基于大规模泌尿系统肿瘤手术数据的分析
Izuki Ogawa,Masanao Shinohara,Naoki Fujita et al.
Izuki Ogawa et al.
Background: Perioperative mortality is usually reported as percentages, although the same risk can also be expressed as natural frequencies (e.g., 1-in-N). Presenting both formats may provide complementary ways of communi...
Insulin resistance assessed by estimated glucose disposal rate and the risk of prostate cancer [0.03%]
基于葡萄糖处置率估计值评价的胰岛素抵抗与前列腺癌发病风险的关系研究
Yuren Zhang,Jinting Xu,Yiping Zhang et al.
Yuren Zhang et al.
Introduction: Estimated glucose disposal rate (eGDR) is a validated surrogate marker of insulin sensitivity derived from clinical metabolic parameters. This study investigated the association between eGDR and prostate can...
Ankit Misra,Aditya Phadte,Vasanthapriya Subramani et al.
Ankit Misra et al.
Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy arising from the adrenal cortex, characterized by local invasion and frequent distant metastases. Tumor size is a key predictor of malignancy, with lesions larger than 4 cm ...
Androgen receptor splice variant 7 (AR-V7) in castration-resistant prostate cancer: Molecular mechanisms and therapeutic strategies [0.03%]
雄激素受体剪接变体7(AR-V7)在去势抵抗性前列腺癌中的分子机制和治疗策略
Jun Li,Xiong Wang,Xiaoshuang Tang
Jun Li
Androgen receptor splice variant 7 (AR-V7) is a principal driver of resistance to androgen receptor signaling inhibitors in castration-resistant prostate cancer. By virtue of its truncated ligand-binding domain, AR-V7 functions as a constit...
Optimizing radical cystectomy recovery: The role of modified ERAS in improving postoperative outcomes [0.03%]
改良ERAS在膀胱癌根治术快速康复中的应用价值研究
Randie E White,Joshua A Linscott,Connor Pelletier et al.
Randie E White et al.
Purpose: Radical cystectomy (RC) is associated with high rates of postoperative complications and readmissions. Despite the adoption of enhanced recovery after surgery (ERAS) protocols, there was no reduction in our compl...
Herney Andrés García-Perdomo,Angélica María Dávila-Raigoza,Philippe E Spiess
Herney Andrés García-Perdomo
Primary urethral carcinoma (PUC) is a very rare and aggressive genitourinary cancer. Its low incidence has limited the availability of clinical trials and robust information, with most evidence derived from retrospective series, population-...
Early oncologic and functional outcomes of partial gland high-intensity focused ultrasound (HIFU) for prostate cancer: First 110 cases at a large U.S. tertiary referral center [0.03%]
美国大型三级转诊中心部分腺体高强度聚焦超声(HIFU)治疗前列腺癌的早期疗效及功能结局报告(首110例)
Eric M Lo,Michael Luu,Sanjay Das et al.
Eric M Lo et al.
Introduction: High-intensity focused ultrasound (HIFU) is increasingly being used in the United States for primary treatment of localized prostate cancer, but there is limited evidence documenting outcomes during the init...
Sex-based prognostic differences in upper tract urothelial carcinoma: A multicenter cohort study from Taiwan [0.03%]
来自台湾的多中心队列研究:尿路上皮癌的性别预后差异
Hao-Han Chang,Yao-Chou Tsai,Chih-Chin Yu et al.
Hao-Han Chang et al.
Objective: To investigate sex-based differences in oncologic outcomes and prognostic factors in patients with upper tract urothelial carcinoma (UTUC) undergoing radical nephroureterectomy (RNU) in a large multicenter coho...