The predictive value of lesion density in enhancing multiparametric MRI for detecting clinically significant prostate cancer [0.03%]
增强多参数MRI上病灶密度对临床意义前列腺癌的预测价值
Ali Khatib,Zizo Al-Daqqaq,Anna J Black et al.
Ali Khatib et al.
Purpose: The aim of this study was to evaluate the predictive value of lesion density on mpMRI for detecting clinically significant prostate cancer (csPCa) in men undergoing targeted prostate biopsy. ...
Molecular pathology of rare histologic variants and treatment-resistant lineages of prostate cancer [0.03%]
前列腺癌罕见组织学变异及耐药谱系的分子病理学
Ryuta Watanabe,Noriyoshi Miura,Tadahiko Kikugawa et al.
Ryuta Watanabe et al.
Rare histological variants of prostate cancer-including ductal adenocarcinoma, intraductal carcinoma of the prostate (IDC-P), neuroendocrine carcinoma, basal cell/adenoid cystic carcinoma, squamous cell carcinoma, sarcomatoid carcinoma, and...
Efficacy and safety of tislelizumab plus intravesical chemotherapy in recurrent high-risk non-muscle-invasive bladder cancer: A retrospective single-center real-world study [0.03%]
替雷利珠单抗联合膀胱灌注化疗治疗复发高危非肌层浸润性膀胱癌的疗效及安全性：一项回顾性的单中心真实世界研究
Qing Chen,Rongpan Wu,Chen Zhang et al.
Qing Chen et al.
Background: Recurrent high-risk non-muscle-invasive bladder cancer (HR-NMIBC) poses significant therapeutic challenges due to frequent recurrences. Bacillus Calmette-Guérin (BCG) therapy limitations including global shor...
Circulating tumor DNA in urothelial cancer as an intermediate disease state between localized and advanced stages: Moving from risk factors to micrometastatic disease in the perioperative setting [0.03%]
尿路上皮癌的循环肿瘤DNA作为局限期和晚期之间的中间阶段疾病：从危险因素到围手术期微转移疾病的转变
Sergio Bracarda,Giulia Mammone,Claudia Mosillo et al.
Sergio Bracarda et al.
Urothelial carcinoma, especially muscle-invasive bladder cancer, presents a high risk of recurrence despite curative-intent surgery and perioperative therapies. A major clinical challenge remains the early identification of micrometastatic ...
Lack of survival benefit of pelvic lymph node dissection for patients with radical prostatectomy and postprostatectomy radiotherapy [0.03%]
根治性前列腺切除术后盆腔淋巴结清扫术的生存效益不足
Isaac E Kim Jr,Dhruv Puri,Nityam Rathi et al.
Isaac E Kim Jr et al.
Introduction and objective: The survival benefit of pelvic lymph node dissection (PLND) during radical prostatectomy (RP) remains unclear. Recent guidelines suggest that PLND may be therapeutic in subsets of patients with...
Distinct pathways of disease progression with dual checkpoint blockade versus immunotargeted therapy in metastatic renal cell carcinoma [0.03%]
转移性肾细胞癌中双重检查点抑制与免疫靶向治疗的不同发病机制路径
Ilya Tsimafeyeu,Fuad Guliyev,Bakytzhan Ongarbayev et al.
Ilya Tsimafeyeu et al.
Background: Patterns of progression under immuno-oncology regimens in metastatic renal cell carcinoma (mRCC) remain poorly described. This study characterizes site-specific disease progression in patients receiving first-...
Surgical operation duration as a predictor of venous thromboembolism risk after radical cystectomy [0.03%]
根治性膀胱全切术中手术时间对术后静脉血栓栓塞风险的预测作用
Furkan Dursun,Burak Akgul,Jonathan A Gelfond et al.
Furkan Dursun et al.
Objective: We assess the impact of operation duration (OD) on the occurrence of symptomatic venous thromboembolism (VTE) in patients undergoing radical cystectomy (RC). We also seek to determine a threshold OD and quantif...
Pharmacologic synergy versus independent action in androgen receptor-axis-targeted agent-docetaxel triplet therapy for metastatic hormone-sensitive prostate cancer: a copula-based analysis [0.03%]
基于佐值分析的雄激素受体轴靶向药物多西他赛三联疗法在转移性激素敏感型前列腺癌治疗中的药理协同作用与独立作用：一项基于佐值分析的研究
Wei Chen,Soichiro Yoshida,Shugo Yajima et al.
Wei Chen et al.
Background: Triplet therapy combining androgen deprivation therapy (ADT), docetaxel, and androgen receptor-axis-targeted agents (ARATs) has exhibited survival benefits in metastatic hormone-sensitive prostate cancer (mHSP...
Does the urinary microbiome reflect the bladder-cancer-associated microbiome? Characterizing the microbiome in urine and cancer tissue in bladder cancer [0.03%]
尿液微生物组反映膀胱肿瘤相关微生物组吗？膀胱癌患者尿液和肿瘤标本的微生物表征
Ahmed A Hussein,Yakov Klugman,Jordan Carlson et al.
Ahmed A Hussein et al.
Introduction: We sought to characterize the microbiome in bladder cancer tissue samples and to compare it with the microbiome in simultaneously collected urine. ...
LncRNA NPSR1-AS1 affects the malignant biological behavior of bladder cancer through miR-199a-3p and the clinical value of urine-derived lncRNA NPSR1-AS1 [0.03%]
lncRNA NPSR1-AS1通过miR-199a-3p影响膀胱癌的恶性生物学行为及其尿源性lncRNA NPSR1-AS1的临床价值
Weijing He,Yong Wen,Huiling Qin
Weijing He
Background: The alteration of long noncoding RNA (lncRNA) expression is significantly associated with the occurrence and progression of various human tumors. ...