Investigating Direct and Indirect Genetic Effects in Attention-Deficit/Hyperactivity Disorder Using Parent-Offspring Trios [0.03%]
采用父母子三联体研究注意缺陷多动障碍的直接和间接遗传效应
Joanna Martin,Matthew Wray,Sharifah Shameem Agha et al.
Joanna Martin et al.
Background: Attention-deficit/hyperactivity disorder (ADHD) is highly heritable, but little is known about the relative effects of transmitted (i.e., direct) and nontransmitted (i.e., indirect) common variant risks. Using...
Etiopathogenic Models of Psychosis Spectrum Illnesses Must Resolve Four Key Features [0.03%]
精神病谱系障碍的病因学模型必须解决四个关键问题
Sophia Vinogradov,Arif A Hamid,A David Redish
Sophia Vinogradov
Etiopathogenic models for psychosis spectrum illnesses are converging on a number of key processes, such as the influence of specific genes on the synthesis of proteins important in synaptic functioning, alterations in how neurons respond t...
Linking Individual Differences in Personalized Functional Network Topography to Psychopathology in Youth [0.03%]
基于个体差异的个性化功能网络拓扑与青少年精神症状的关系
Zaixu Cui,Adam R Pines,Bart Larsen et al.
Zaixu Cui et al.
Background: The spatial layout of large-scale functional brain networks differs between individuals and is particularly variable in the association cortex, implicated in a broad range of psychiatric disorders. However, it...
Persistent Child and Adolescent Anxiety Predicts Development of Psychotic Disorders via Elevated Inflammation [0.03%]
持久的儿童和青少年焦虑通过升高炎症预测精神分裂症的发展
Laura Jayne Westacott
Laura Jayne Westacott
Meike D Hettwer,Amin Saberi,Yun-Shuang Fan et al.
Meike D Hettwer et al.
Anita Sathyanarayanan,Divya Mehta
Anita Sathyanarayanan
Quo Vaditis Anti-Brain Autoantibodies: Causes, Consequences, or Epiphenomena? [0.03%]
反脑自身抗体 quo vadis ：病因、后果还是伴随现象？
Hannelore Ehrenreich,Vinicius Daguano Gastaldi,Justus B H Wilke
Hannelore Ehrenreich
Positive Allosteric Modulation of mGlu1 Reverses Cocaine-Induced Behavioral and Synaptic Plasticity Through the Integrated Stress Response and Oligophrenin-1 [0.03%]
metabotropic谷氨酸受体1(mGlu1)正向别构调节通过整合应激反应和Oligophrenin-1逆转可卡因引起的表型和突触可塑性变化
Alex B Kawa,Eun-Kyung Hwang,Jonathan R Funke et al.
Alex B Kawa et al.
Background: Cue-induced cocaine craving progressively intensifies (incubates) during abstinence from cocaine self-administration. Expression of incubated cocaine craving depends on elevated calcium-permeable AMPA receptor...
Hallucinations and Brain Morphology Across Early Adolescence: A Longitudinal Neuroimaging Study [0.03%]
青春期早期幻觉与脑形态学的纵向神经影像研究
Lisa R Steenkamp,Elisabet Blok,Ryan L Muetzel et al.
Lisa R Steenkamp et al.
Background: Psychotic disorders have been widely associated with structural brain abnormalities. However, it is unclear whether brain structure predicts psychotic experiences in youth from the general population, owing to...
Prenatal Maternal Distress During the COVID-19 Pandemic and Associations With Infant Brain Connectivity [0.03%]
新冠肺炎疫情下的孕期母体压力与婴儿大脑连接性的关联研究
Kathryn Y Manning,Xiangyu Long,Dana Watts et al.
Kathryn Y Manning et al.
Background: The COVID-19 pandemic has caused substantially elevated distress in pregnant individuals, which has the potential to affect the developing infant brain. Our main objective was to understand how prenatal distre...