Francesca Puppo,Alysson Renato Muotri
Francesca Puppo
Juli Wang,Robert Weatheritt,Irina Voineagu
Juli Wang
The higher-order cognitive functions observed in primates correlate with the evolutionary enhancement of cortical volume and folding, which in turn are driven by the primate-specific expansion of cellular diversity in the developing cortex....
Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine [0.03%]
氟西汀抗抑郁作用的阿片系统贡献
Elena Carazo-Arias,Phi T Nguyen,Marley Kass et al.
Elena Carazo-Arias et al.
Background: Selective serotonin reuptake inhibitors such as fluoxetine have a limited treatment efficacy. The mechanism by which some patients respond to fluoxetine while others do not remains poorly understood, limiting ...
Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis: A Simple Solution [0.03%]
全基因组关联研究元分析中遗传度估计普遍存在偏低的现象及简单解决方案
Andrew D Grotzinger,Javier de la Fuente,Florian Privé et al.
Andrew D Grotzinger et al.
Background: Single nucleotide polymorphism-based heritability is a fundamental quantity in the genetic analysis of complex traits. For case-control phenotypes, for which the continuous distribution of risk in the populati...
Polygenic Liability to Depression Is Associated With Multiple Medical Conditions in the Electronic Health Record: Phenome-wide Association Study of 46,782 Individuals [0.03%]
抑郁症多基因易感性与电子健康记录中的多种疾病相关：46,782人的表型组关联研究
Yu Fang,Lars G Fritsche,Bhramar Mukherjee et al.
Yu Fang et al.
Background: Major depressive disorder (MDD) is a leading cause of disease-associated disability, with much of the increased burden due to psychiatric and medical comorbidity. This comorbidity partly reflects common geneti...
A Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder-Associated Impairment in Early Childhood [0.03%]
基于数据驱动的方法在无偏差样本中的应用揭示了自闭症谱系障碍相关损害在早期儿童时期的性别比相等
Catherine A Burrows,Rebecca L Grzadzinski,Kevin Donovan et al.
Catherine A Burrows et al.
Background: Sex differences in the prevalence of neurodevelopmental disorders are particularly evident in autism spectrum disorder (ASD). Heterogeneous symptom presentation and the potential of measurement bias hinder ear...
Overlap of Neuroanatomical Involvement in Frontotemporal Dementia and Primary Psychiatric Disorders: A Meta-analysis [0.03%]
额颞叶痴呆和原发性精神疾病神经解剖学改变的重叠：一项 meta 分析
Hulya Ulugut,Calvin Trieu,Colin Groot et al.
Hulya Ulugut et al.
Background: Despite significant symptomatic overlap between behavioral variant frontotemporal dementia (bvFTD) and primary psychiatric disorders (PPDs), a potential overlap in their structural anatomical changes has not b...
Neural Pathway for Gut Feelings: Vagal Interoceptive Feedback From the Gastrointestinal Tract Is a Critical Modulator of Anxiety-like Behavior [0.03%]
肠道感觉的神经通道：迷走神经介导的内脏感受性信号是焦虑样行为的关键调节因素
Jean-Philippe Krieger,Mohammed Asker,Pauline van der Velden et al.
Jean-Philippe Krieger et al.
Background: Anxiety disorders are associated with an altered perception of the body's internal state. Therefore, understanding the neuronal basis of interoception can foster novel anxiety therapies. In rodents, the feedin...
Published Erratum
Biological psychiatry. 2022 Oct 1;92(7):603. DOI:10.1016/j.biopsych.2022.07.015 2022
Somatodendritic Release of Cholecystokinin Potentiates GABAergic Synapses Onto Ventral Tegmental Area Dopamine Cells [0.03%]
胆囊收缩素的 soma-dendritic 发放增强投射到腹侧被盖区多巴胺能神经元的GABA能突触作用
Valentina Martinez Damonte,Matthew B Pomrenze,Claire E Manning et al.
Valentina Martinez Damonte et al.
Background: Neuropeptides are contained in nearly every neuron in the central nervous system and can be released not only from nerve terminals but also from somatodendritic sites. Cholecystokinin (CCK), among the most abu...