Role of PPAR-Allopregnanolone Signaling in Behavioral and Inflammatory Gut-Brain Axis Communications [0.03%]
PPAR-allopregnanolone信号在行为和炎症肠-脑轴交流中的作用
Graziano Pinna
Graziano Pinna
The gut microbiome regulates emotional behavior, stress responses, and inflammatory processes by communicating with the brain. How and which neurobiological mediators underlie this communication remain poorly understood. PPAR-α (peroxisome...
Published Erratum
Biological psychiatry. 2023 May 15;93(10):953. DOI:10.1016/j.biopsych.2023.03.016 2023
Marisa N Spann,Cynthia Rogers
Marisa N Spann
Microglia Transcriptional Profiling in Major Depressive Disorder Shows Inhibition of Cortical Gray Matter Microglia [0.03%]
抑郁症中微胶质细胞转录组分析显示皮层灰质中微胶质细胞活性抑制
Karel W F Scheepstra,Mark R Mizee,Jackelien van Scheppingen et al.
Karel W F Scheepstra et al.
Background: Microglia have been implicated in the pathophysiology of major depressive disorder (MDD), but information on biological mechanisms is limited. Therefore, we investigated the gene expression profile of microgli...
Developmental Changes in Habenular and Striatal Social Reinforcement Responsivity Across Adolescence Linked With Substance Use [0.03%]
青少年腹下核和纹状体社交强化反应性随年龄的变化与物质使用有关
Jessica S Flannery,Nathan A Jorgensen,Seh-Joo Kwon et al.
Jessica S Flannery et al.
Background: Habenula (HB) function is implicated in substance use disorders and is involved in inhibiting dopamine release in the ventral striatum (VS). While blunted VS reward responsivity is implicated in risk for later...
The p75 Neurotrophin Receptor in Preadolescent Prefrontal Parvalbumin Interneurons Promotes Cognitive Flexibility in Adult Mice [0.03%]
小胶质细胞迁移因子依赖的髓系细胞促进慢性疼痛中的恐惧和焦虑行为
Pegah Chehrazi,Karen Ka Yan Lee,Marisol Lavertu-Jolin et al.
Pegah Chehrazi et al.
Background: Parvalbumin (PV)-positive GABAergic (gamma-aminobutyric acidergic) cells provide robust perisomatic inhibition to neighboring pyramidal neurons and regulate brain oscillations. Alterations in PV interneuron co...
The Neurogenetics of Functional Connectivity Alterations in Autism: Insights From Subtyping in 657 Individuals [0.03%]
自闭症的功能连接改变的神经遗传学：来自657人分型的见解
Javier Rasero,Antonio Jimenez-Marin,Ibai Diez et al.
Javier Rasero et al.
Background: There is little consensus and controversial evidence on anatomical alterations in the brains of people with autism spectrum disorder (ASD), due in part to the large heterogeneity present in ASD, which in turn ...
40-Hz Auditory Steady-State Responses in Schizophrenia: Toward a Mechanistic Biomarker for Circuit Dysfunctions and Early Detection and Diagnosis [0.03%]
schizophrenia中的40赫兹听觉稳态反应：电路功能障碍的机制生物标志物以及早期检测和诊断的发展方向
Tineke Grent-&#x;t-Jong,Marion Brickwedde,Christoph Metzner et al.
Tineke Grent-&#x;t-Jong et al.
There is converging evidence that 40-Hz auditory steady-state responses (ASSRs) are robustly impaired in schizophrenia and could constitute a potential biomarker for characterizing circuit dysfunctions as well as enable early detection and ...
Identifying Neurophysiological Markers of Intermittent Theta Burst Stimulation in Treatment-Resistant Depression Using Transcranial Magnetic Stimulation-Electroencephalography [0.03%]
利用经颅磁刺激脑电图识别间歇式θ爆发刺激治疗难治性抑郁的神经生理标志物
Rebecca Strafella,Davide Momi,Reza Zomorrodi et al.
Rebecca Strafella et al.
Background: Intermittent theta burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex is effective for treatment-resistant depression, but the effects of iTBS on neurophysiological markers remain uncle...
Randomized Controlled Trial
Biological psychiatry. 2023 Sep 15;94(6):454-465. DOI:10.1016/j.biopsych.2023.04.011 2023