Cannabidiol attenuates heroin seeking in male rats associated with normalization of discrete neurobiological signatures within the nucleus accumbens with subregional specificity [0.03%]
大麻二酚通过调节伏隔核亚区的表型正常化作用来缓解雄性大鼠的海洛因寻求行为
Alexandra Chisholm,Jacqueline-Marie N Ferland,Randall J Ellis et al.
Alexandra Chisholm et al.
Background: Opioid use disorder is a chronic relapsing condition characterized by cycles of compulsive drug use, abstinence, and relapse. Cannabidiol (CBD), a non-intoxicating cannabinoid, is under investigation as an ant...
Context Matters: Sex and Social Status Impact Cocaine's Effects on Kappa Opioid Receptors [0.03%]
环境影响性别和社交地位对可卡因作用于κ阿片受体的影响
Yasmin Zakiniaeiz,Kelly Patricia Cosgrove
Yasmin Zakiniaeiz
Dynamic Cytokine Relationships Across the Blood-Brain Barrier in Humans and Non-Human Primates, Implications for Psychiatric Illness: A Systematic Review [0.03%]
人和非人类灵长类动物血脑屏障细胞因子动态关系与精神病发病机制的系统评价：对精神疾病的意义
Rahul Tyagi,Christopher M Bartley
Rahul Tyagi
Cytokines are immune signaling molecules that also function as neuromodulators. Cytokines are elevated in the peripheral blood of some individuals with mental disorders, suggesting that inflammation may contribute to their illness. Furtherm...
Overview of Challenges in Brain-based Predictive Modeling: Towards meaningful predictive insights [0.03%]
基于大脑的预测建模面临的挑战综述：迈向有意义的预测洞察
Vera Komeyer,Nicolas Nieto,Simon B Eickhoff et al.
Vera Komeyer et al.
Predictive analytics based on machine learning (ML) and artificial intelligence is a powerful tool enabling precision psychiatry and providing insights into brain-behavior relationships. However, given the mixed results observed in the fiel...
Published Erratum
Biological psychiatry. 2025 Sep 12:S0006-3223(25)01431-3. DOI:10.1016/j.biopsych.2025.08.014 2025
Distinct Amygdala Neuronal Populations Control Opioid Use and Withdrawal in Mice [0.03%]
控制小鼠阿片使用和戒断的不同的杏仁核神经元群落
Lucas Silva Tortorelli,Henry Zin Oo,Suyun Hahn et al.
Lucas Silva Tortorelli et al.
Background: Opioid use disorder (OUD) is a chronic and recurring psychiatric disorder that is associated with high morbidity and mortality. The central nucleus of the amygdala (CeA) undergoes neuroadaptations in both huma...
Developing Clinically Interpretable Neuroimaging Biotypes in Psychiatry [0.03%]
精神病学中可临床解释的神经影像生物标志物的发展
Jeesung Ahn,Lara Foland-Ross,Teddy J Akiki et al.
Jeesung Ahn et al.
Despite available treatments, major depressive disorder (MDD) remains one of the leading causes of disability across medical conditions. The current symptom-based diagnostic system groups patients with highly heterogeneous presentations, wi...
Sarah M Banker,Matthew Schafer,Sarah Barkley et al.
Sarah M Banker et al.
Background: As we navigate changing social landscapes, maintaining maps of interpersonal dynamics can help guide our choices. Autism spectrum disorder (ASD) is associated with social challenges that may affect the accumul...