Psychotropic Taxonomies: Constructing a Therapeutic Framework for Psychiatry [0.03%]
精神药物分类学：构建精神病学的治疗框架
Robert A McCutcheon,Philip Cowen,Matthew M Nour et al.
Robert A McCutcheon et al.
Pharmacological interventions are a cornerstone of psychiatric practice. The taxonomies used to classify these interventions influence the treatment and interpretation of psychiatric symptoms. Disease-based classification systems (e.g., 'an...
Justin Buck,Guillermo Horga
Justin Buck
Clinical Phenotypes Associated With White Matter Microstructural Abnormalities Across Early Psychoses [0.03%]
与早期精神病白质微结构异常相关的临床表型
Godfrey D Pearlson
Godfrey D Pearlson
Deep Brain Stimulation of the Nucleus Accumbens for Severe Self-Injurious Behaviour in Children: A Phase I Pilot Trial [0.03%]
针对儿童严重自伤行为的伏隔核深部脑刺激疗法一期临床试验
Carolina Gorodetsky,Karim Mithani,Sara Breitbart et al.
Carolina Gorodetsky et al.
Background: Self-injurious behaviours (SIB) are repetitive, non-accidental movements that result in physical damage inflicted upon oneself, without suicidal intent. SIB are prevalent among children with autism spectrum di...
PsyRiskMR: a comprehensive resource for identifying psychiatric disorders risk factors through Mendelian randomization [0.03%]
PsyRiskMR：通过孟德尔随机化识别精神疾病风险因素的全面资源
Xiaoyan Li,Aotian Shen,Lingli Fan et al.
Xiaoyan Li et al.
Background: Psychiatric disorders pose an enormous economic and emotional burden on individuals, their families and society. Given that the current analysis of the pathogenesis of psychiatric disorders remains challenging...
Variations in brain glutamate and glutamine levels throughout the sleep-wake cycle [0.03%]
睡眠觉醒周期中大脑谷氨酸和谷氨酰胺水平的变化规律
Sujung Yoon,Suji Lee,Yoonji Joo et al.
Sujung Yoon et al.
Background: Glutamatergic signaling is essential for modulating synaptic plasticity and cognition. However, the dynamics of glutamatergic activity over the 24-hour sleep-wake cycle, particularly in relation to sleep, rema...
CNVs and Human Well-being: Integrating Psychiatric, Physical, and Socioeconomic Perspectives [0.03%]
拷贝数变异与人类福祉：整合精神病学、物理和经济社会学视角
Itaru Kushima,Masahiro Nakatochi,Norio Ozaki
Itaru Kushima
Copy number variations (CNVs) have emerged as crucial genetic factors influencing a wide spectrum of human health outcomes, with particularly strong associations to psychiatric disorders. This review presents a synthesis of diverse impacts ...
Data-driven analysis identifies novel modulation of social behavior in female mice witnessing chronic social defeat stress [0.03%]
数据驱动分析发现了慢性社会挫败压力下雌性小鼠社交行为的新调控模式
Heike Schuler,Rand S Eid,Serena Wu et al.
Heike Schuler et al.
Background: Chronic social defeat stress is a widely used depression model in male mice. Several proposed adaptations extend this model to females with variable, often marginal effects. We examine if the widely used male-...
Maternal Immune Activation and Endocannabinoid System: Focus on Two-Hit Models of Schizophrenia [0.03%]
母体免疫激活和内源大麻素系统：精神分裂症双重打击模型的研究重点
Michele Santoni,Marco Pistis
Michele Santoni
The devastating effects of the COVID-19 pandemic have underscored the significant threat infectious diseases pose to our society. Pregnancy represents a particularly vulnerable period for infections, which can compromise maternal health and...