Intimate Partner Violence during Pregnancy and Early Offspring Development:A Prospective Birth Cohort Study [0.03%]
孕期伴侣暴力对子代早期发展的影响：前瞻性出生队列研究
Nan Jiang,Shuang-Shuang Ma,Ping Zu et al.
Nan Jiang et al.
Background: Intimate partner violence (IPV) during pregnancy is linked to several unfavorable outcomes for both mothers and babies. However, few studies have examined its connections to early infant neurodevelopment, and ...
Jianfeng Liu,Michael S Totty,Hugo Bayer et al.
Jianfeng Liu et al.
Decades of research have established a critical role of the basolateral complex of the amygdala (BLA) in the encoding and storage of aversive memories. Much of this work utilizes Pavlovian fear conditioning procedures in which animals exper...
Carlie Neiswanger,Micaela V Ruiz,Kandace Kimball et al.
Carlie Neiswanger et al.
Background: The endogenous dynorphin/kappa opioid receptor (KOR) system in the brain mediates the dysphoric effects of stress, and KOR antagonists may have therapeutic potential for the treatment of drug addiction, depres...
Brain Network Resilience and Cognitive Function in Patients with First Episode Schizophrenia Spectrum Disorders [0.03%]
首次发作谱系精神分裂症患者的脑网络弹性和认知功能
Soyolsaikhan Odkhuu,XiaoChen Tang,Woo-Sung Kim et al.
Soyolsaikhan Odkhuu et al.
Background: First-episode schizophrenia spectrum disorders (FESSDs) are associated with significant cognitive impairment that affects daily functioning. While these deficits are well-documented, the neural mechanisms unde...
Astrid M Cardona-Acosta,Lyonna F Parise,Carlos A Bolaños-Guzmán et al.
Astrid M Cardona-Acosta et al.
The prevalence of stress-induced disorders, including depression, anxiety, PTSD, and postpartum depression, has been increasing, while current treatment approaches are limited. As a result, researchers are exploring alternative treatments t...
Neurochemical and Circuit Heterogeneity of Cognition-Modulating Prefrontal Corticotropin-Releasing Factor Neurons [0.03%]
调控认知的前额叶促肾上腺皮质激素释放因子神经元的神经化学及回路异质性
Spencer K Cooke,Andrea J Martin,Robert C Spencer et al.
Spencer K Cooke et al.
Background: Impairment of prefrontal cortex (PFC)-dependent cognition is associated with multiple psychiatric disorders. Development of more effective treatments for this form of cognitive dysfunction is hindered by our l...
Mendelian randomization reveals causalities between DNA methylation and schizophrenia [0.03%]
孟德尔随机化揭示了DNA甲基化与精神分裂症之间的因果关系
Danni Wang,Danyang Li,Xinglun Dang et al.
Danni Wang et al.
Background: Epigenetic factors (such as DNA methylation) have been widely reported to be associated with schizophrenia (SCZ). However, the causal relationships between epigenetic factors and SCZ remain largely unknown. ...
Novel multimodal precision medicine approaches and the relevance of developmental trajectories in bipolar disorder [0.03%]
双相情感障碍中的新型多模式精准医疗方法及发育轨迹的相关性
Olav B Smeland,Cecilie Busch,Ole A Andreassen et al.
Olav B Smeland et al.
There is a pressing need to establish objective measures to improve diagnosis, prediction, prevention and treatment of bipolar disorder (BD). Multimodal artificial intelligence (AI) tools could provide these means by incorporating various l...
Benjamin Zebley,Conor Liston
Benjamin Zebley
Not All Neuroinflammation Is Created Equal: The Dual Nature of Astrogliosis [0.03%]
并非所有的神经炎症都一样：星形胶质细胞增生的二重性
Ebrahim Haroon,Jennifer C Felger,Andrew H Miller
Ebrahim Haroon