New genomics discoveries across the bipolar disorder spectrum implicate neurobiological and developmental pathways [0.03%]
跨情绪双相障碍谱系的新的基因组学发现涉及神经生物学和发育途径
Kevin S O&#x;Connell,Rolf Adolfsson,Till F M Andlauer et al.
Kevin S O&#x;Connell et al.
Bipolar disorder (BD) is a highly heritable mental disorder that affects millions of people worldwide. Our understanding of the genetic etiology and biological processes underlying BD have greatly increased in recent years. Extensive progre...
Uncovering the Genetic Architecture of Differentiation Between Childhood Behavioral and Emotional Problems: A Predominant Overlap With Neurodevelopmental Conditions [0.03%]
揭示儿童行为和情绪问题差异的遗传架构：与神经发育状况的主要重叠
Geneviève Morneau-Vaillancourt
Geneviève Morneau-Vaillancourt
A Beacon of Hope: Deep Brain Stimulation for Treatment-Refractory Self-Injurious Behavior in Children [0.03%]
一束希望之光：儿童难治性自伤行为的深部脑刺激治疗
Jordan J Lo,Stephen Z Shapiro,Lora W Kahn
Jordan J Lo
Sex and hormonal effects on drug cue-reactivity and its regulation in human addiction [0.03%]
性别和激素在人类药物成瘾中的药理线索诱发及调节作用
Yuefeng Huang,Eduardo R Butelman,Ahmet O Ceceli et al.
Yuefeng Huang et al.
Background: The underlying cortico-striatal mechanisms of sex and hormonal effects in addiction are unknown, limiting the development of personalized treatments. ...
Integrating Knowledge: The Power of Ontologies in Psychiatric Research and Clinical Informatics [0.03%]
整合知识：精神医学研究与临床信息学中的本体论力量
Melvin G McInnis,Ben Coleman,Eric Hurwitz et al.
Melvin G McInnis et al.
Ontologies are structured frameworks for representing knowledge by systematically defining concepts, categories, and their relationships. While widely adopted in biomedicine, ontologies remain largely absent in mental health research and cl...
Neonatal brain volumes and early parenting behavior as mediators in associations between prenatal social disadvantage and socioemotional problems in toddlers [0.03%]
孕期社会不利因素对幼儿情绪问题影响的介导因素：新生儿脑容量及早期教养方式的作用
Shelby D Leverett,Olivia Poolos,Rebecca G Brady et al.
Shelby D Leverett et al.
Background: Social disadvantage has been associated with early socioemotional difficulties. This study examined mechanisms that relate prenatal social disadvantage (PSD) to the development of early socioemotional problems...
Greater neuroimmune system deficit in women than men with alcohol use disorder [0.03%]
酒精使用障碍患者的神经免疫系统缺陷：女性比男性更为严重
Yasmin Zakiniaeiz,Ansel T Hillmer,Hannah Shi et al.
Yasmin Zakiniaeiz et al.
Background: Women who drink are more vulnerable than men to many of the consequences of alcohol use, including alcohol-related cancers, cardiovascular disease, liver cirrhosis, and immune system dysfunction. Acute alcohol...
Understanding the neurobiology and computational mechanisms of social conformity: implications for psychiatric disorders [0.03%]
理解社会从众行为的神经生物学和计算机制：对精神病障碍的意义
Yutong Li,Yafeng Pan,Di Zhao
Yutong Li
Social conformity and psychiatric disorders share overlapping brain regions and neural pathways, arousing our interest in uncovering their potentially shared underlying neural and computational mechanisms. Critically, the dynamics of group ...