Alternative sources and metabolic engineering of Taxol: Advances and future perspectives [0.03%]
Taxol的替代来源及其代谢工程：进展与展望
Mohammad Sabzehzari,Masoumeh Zeinali,Mohammad Reza Naghavi
Mohammad Sabzehzari
Paclitaxel is one of the strong plant-derived anti-cancer drugs that was first isolated from the Pacific yew. Despite many paclitaxel's clinical successes, the limited accessibility of paclitaxel for clinical trials is recognized as the mos...
Glycoside hydrolase family 18 chitinases: The known and the unknown [0.03%]
家族18糖苷水解酶(chitinase)：已知与未知方面
Wei Chen,Xi Jiang,Qing Yang
Wei Chen
Glycoside hydrolase family 18 (GH18) chitinases, which catalyze the biodegradation of β-1,4 glycosidic bond in amino polysaccharides via a substrate-assisted retention mechanism, are widely distributed in nature and have diverse functions....
Tania Chroumpi,Miia R Mäkelä,Ronald P de Vries
Tania Chroumpi
Filamentous fungi are important industrial cell factories used for the production of a wide range of enzymes and metabolites. Their primary metabolism is a significant source of industrially important compounds, as well as of monomeric buil...
Mehmooda Fayyaz,Kit Wayne Chew,Pau Loke Show et al.
Mehmooda Fayyaz et al.
Microalgae-based bioproducts are in limelight because of their promising future, novel characteristics, the current situation of population needs, and rising prices of rapidly depleting energy resources. Algae-based products are considered ...
Production of plant natural products through engineered Yarrowia lipolytica [0.03%]
利用工程假丝酵母生产植物天然产物
Akram Muhammad,Xudong Feng,Aamir Rasool et al.
Akram Muhammad et al.
Plant natural products have broad applications in the pharmaceutical, food, cosmetics and flavor industries. However, the current manufacturing methods for plant natural products mainly rely on plant extraction and chemical synthesis, which...
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing [0.03%]
哺乳动物细胞培养生产重组蛋白：生物制造关键步骤综述
Róisín O&#x;Flaherty,Adam Bergin,Evangelia Flampouri et al.
Róisín O&#x;Flaherty et al.
The manufacturing of recombinant protein is traditionally undertaken in mammalian cell culture. Today, speed, cost and safety are the primary considerations for process improvements in both upstream and downstream manufacturing. Leaders in ...
Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation [0.03%]
黄酮类、萜类和聚酮抗生素：糖基化的作用及糖基工程的生物催化策略
Ushasree Mrudulakumari Vasudevan,Eun Yeol Lee
Ushasree Mrudulakumari Vasudevan
Flavonoids, terpenoids, and polyketides are structurally diverse secondary metabolites used widely as pharmaceuticals and nutraceuticals. Most of these molecules exist in nature as glycosides, in which sugar residues act as a decisive facto...
Jubair Ahmed,Merve Gultekinoglu,Mohan Edirisinghe
Jubair Ahmed
Bacterial cellulose (BC) is cellulose produced by a few limited species of bacteria in given conditions. BC has many remarkable properties such as its attractive mechanical properties, water uptake ability and biocompatibility which makes i...
Aubrey M Demchuk,Trushar R Patel
Aubrey M Demchuk
Protein nanocompartments (PNCs) are self-assembling biological nanocages that can be harnessed as platforms for a wide range of nanobiotechnology applications. The most widely studied examples of PNCs include virus-like particles, bacterial...
Common problems associated with the microbial productions of aromatic compounds and corresponding metabolic engineering strategies [0.03%]
微生物生产芳香化合物的常见问题及相应的代谢工程策略
Meijie Li,Changqing Liu,Jianming Yang et al.
Meijie Li et al.
Recent progress in metabolic engineering and synthetic biology has enabled the production of valuable chemicals in microbial cell factories from renewable feedstocks. High value-added aromatic compounds, most of which are traditionally chem...