Cultivation processes to select microorganisms with high accumulation ability [0.03%]
培养筛选高效微生物积累菌种的工艺
Fabrizio Di Caprio
Fabrizio Di Caprio
The microbial ability to accumulate biomolecules is fundamental for different biotechnological applications aiming at the production of biofuels, food and bioplastics. However, high accumulation is a selective advantage only under certain s...
Genetic toolkits for engineering Rhodococcus species with versatile applications [0.03%]
具有广泛用途的红球菌属遗传工具箱
Youxiang Liang,Huimin Yu
Youxiang Liang
Rhodococcus spp. are a group of non-model gram-positive bacteria with diverse catabolic activities and strong adaptive capabilities, which enable their wide application in whole-cell biocatalysis, environmental bioremediation, and lignocell...
Application of microbial 3-ketosteroid Δ1-dehydrogenases in biotechnology [0.03%]
微生物3-酮固醇Δ1-脱氢酶的生物技术应用
Ali Rohman,Bauke W Dijkstra
Ali Rohman
3-Ketosteroid Δ1-dehydrogenase catalyzes the 1(2)-dehydrogenation of 3-ketosteroid substrates using flavin adenine dinucleotide as a cofactor. The enzyme plays a crucial role in microbial steroid degradation, both under aerobic and anaerob...
Using machine learning approaches for multi-omics data analysis: A review [0.03%]
用于组学数据整合分析的机器学习方法综述
Parminder S Reel,Smarti Reel,Ewan Pearson et al.
Parminder S Reel et al.
With the development of modern high-throughput omic measurement platforms, it has become essential for biomedical studies to undertake an integrative (combined) approach to fully utilise these data to gain insights into biological systems. ...
Challenges in biodegradation of non-degradable thermoplastic waste: From environmental impact to operational readiness [0.03%]
不可降解热塑性塑料废物的生物降解挑战：从环境影响到运行准备就绪性
Navid Taghavi,Isuru Abeykoon Udugama,Wei-Qin Zhuang et al.
Navid Taghavi et al.
Non-degradable plastics such as polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyethylene terephthalate (PET) are among the most generated plastic wastes in municipal and industrial waste streams. The mismanagement of abando...
Maria Del Mar Cendra,Eduard Torrents
Maria Del Mar Cendra
Pseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact with a broad range of microorganisms have a substantial clinical impact. This review focuses on the main traits of P. aeruginosa biofilms, such as the...
Pawel Sledzinski,Magdalena Dabrowska,Mateusz Nowaczyk et al.
Pawel Sledzinski et al.
As the possibilities of CRISPR-Cas9 technology have been revealed, we have entered a new era of research aimed at increasing its specificity and safety. This stage of technology development is necessary not only for its wider application in...
Maria Martin-Pascual,Christos Batianis,Lyon Bruinsma et al.
Maria Martin-Pascual et al.
Pseudomonas putida is a microbial chassis of huge potential for industrial and environmental biotechnology, owing to its remarkable metabolic versatility and ability to sustain difficult redox reactions and operational stresses, among other...
Zuzana Mészáros,Pavlína Nekvasilová,Pavla Bojarová et al.
Zuzana Mészáros et al.
Until recently, glycosidases, naturally hydrolyzing carbohydrate-active enzymes, have found few synthetic applications in industry, being primarily used for cleaving unwanted carbohydrates. With the establishment of glycosynthase and transg...
Objectives, benefits and challenges of bioreactor systems for the clinical-scale expansion of T lymphocyte cells [0.03%]
生物反应器系统临床规模T淋巴细胞培养的目标、益处及挑战
Timothée Baudequin,Robin Nyland,Hua Ye
Timothée Baudequin
Cell therapies based on T cell have gathered interest over the last decades for treatment of cancers, becoming recently the most investigated lineage for clinical trials. Although results of adoptive cell therapies are very promising, obtai...