The evolving art of creating genetic diversity: From directed evolution to synthetic biology [0.03%]
从定向进化到合成生物学：创造遗传多样性能力的提高
Andrew Currin,Steven Parker,Christopher J Robinson et al.
Andrew Currin et al.
The ability to engineer biological systems, whether to introduce novel functionality or improved performance, is a cornerstone of biotechnology and synthetic biology. Typically, this requires the generation of genetic diversity to explore v...
Plants arabinogalactans: From structures to physico-chemical and biological properties [0.03%]
植物阿拉伯半乳聚糖：从结构到理化及生物性质
S Saeidy,B Petera,G Pierre et al.
S Saeidy et al.
Arabinogalactans (AGs) are plant heteropolysaccharides with complex structures occasionally attached to proteins (AGPs). AGs in cell matrix of different parts of plant are freely available or chemically bound to pectin rhamnogalactan. Type ...
Recent developments in animal venom peptide nanotherapeutics with improved selectivity for cancer cells [0.03%]
具有改善的癌细胞选择性的动物毒液肽纳米治疗剂的最新进展
Julien Giribaldi,Jennifer J Smith,Christina I Schroeder
Julien Giribaldi
Animal venoms are a rich source of bioactive peptides that efficiently modulate key receptors and ion channels involved in cellular excitability to rapidly neutralize their prey or predators. As such, they have been a wellspring of highly u...
From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi [0.03%]
从木质纤维素到塑料：通过真菌降解方法的知识转移
Paul Daly,Feng Cai,Christian P Kubicek et al.
Paul Daly et al.
In this review, we argue that there is much to be learned by transferring knowledge from research on lignocellulose degradation to that on plastic. Plastic waste accumulates in the environment to hazardous levels, because it is inherently r...
Bioproduction process of natural products and biopharmaceuticals: Biotechnological aspects [0.03%]
天然产物和生物药物的生物制造过程：生物技术方面
Ipek Süntar,Sümeyra Çetinkaya,Ülkü Selcen Haydaroğlu et al.
Ipek Süntar et al.
Decades of research have been put in place for developing sustainable routes of bioproduction of high commercial value natural products (NPs) on the global market. In the last few years alone, we have witnessed significant advances in the b...
Recent advances in tuning the expression and regulation of genes for constructing microbial cell factories [0.03%]
调控基因表达和代谢构建微生物细胞工厂的研究进展
Seung-Woon Jung,Jinho Yeom,Jong Seong Park et al.
Seung-Woon Jung et al.
To overcome environmental problems caused by the use of fossil resources, microbial cell factories have become a promising technique for the sustainable and eco-friendly development of valuable products from renewable resources. Constructin...
Microbial biofilms in biorefinery - Towards a sustainable production of low-value bulk chemicals and fuels [0.03%]
生物炼制中的微生物菌胶体-朝向大量生产低价值基础化学品和燃料的可持续之路
Pascal S Leonov,Xavier Flores-Alsina,Krist V Gernaey et al.
Pascal S Leonov et al.
Harnessing the potential of biocatalytic conversion of renewable biomass into value-added products is still hampered by unfavorable process economics. This has promoted the use of biofilms as an alternative to overcome the limitations of tr...
Fermentation transforms the phenolic profiles and bioactivities of plant-based foods [0.03%]
发酵改变植物食品的酚类特征及活性
William Leonard,Pangzhen Zhang,Danyang Ying et al.
William Leonard et al.
Phenolics are a group of compounds derived from plants that have displayed potent biological activities and health-promoting effects. Fermentation is one of the most conventional but still prevalent bioprocessing methods in the food industr...
Quality by design to define critical process parameters for mesenchymal stem cell expansion [0.03%]
基于质量的设计定义间充质干细胞扩增的关键工艺参数
Charlotte Maillot,Caroline Sion,Natalia De Isla et al.
Charlotte Maillot et al.
Stem cell-based therapeutic products could be the key to treat the deadliest current pathologies, ranging from neuro-degenerative to respiratory diseases. However, in order to bring these innovative therapeutics to a commercialization stage...
Cellular pathways of recombinant adeno-associated virus production for gene therapy [0.03%]
重组腺相关病毒载体生产工艺的细胞通路研究
Sha Sha,Andrew J Maloney,Georgios Katsikis et al.
Sha Sha et al.
Recombinant adeno-associated viruses (rAAVs) are among the most important vectors for in vivo gene therapies. With the rapid development of gene therapy, current rAAV manufacturing capacity faces a challenge to meet the emerging demand for ...