Bishuang Chen,Yongyi Zeng,Jiangtao Sha et al.
Bishuang Chen et al.
Vanadium-dependent haloperoxidases (VHPOs) represent a distinct class of halogenating enzymes that catalyze the oxidation of halide ions into hypohalous acids using hydrogen peroxide and a redox-stable vanadate cofactor. In recent years, VH...
The Midas touch: Recombinant antibodies transforming diagnostic platforms [0.03%]
_MAG的黄金手指：重组抗体改变诊断平台游戏规则_
Angela Chiew Wen Ch&#x;ng,Jing Yi Lai,Jia Xuan Yeoh et al.
Angela Chiew Wen Ch&#x;ng et al.
Antibodies, crucial for diagnostics due to their specific antigen-binding, can be identified using in vitro display technologies. Recombinant antibodies are a new generation of antibodies devoid of immunization thus eliminating the need for...
Sensing for early-stage plant disease: From pathogenesis to sensor design [0.03%]
从植物发病机制到传感器设计的植物病害早期检测研究
Junfeng Xie,Wenxuan Xu,Ranhua Xiong et al.
Junfeng Xie et al.
Pathogenic plant diseases pose a serious risk to global food supplies and to the sustainable development of agriculture and forestry. Conventional control strategies, which rely heavily on chemical treatments, can disrupt ecological balance...
Application of CRISPR/Cas9 gene editing system in microalgal metabolic engineering and synthetic strategies of functional food ingredients [0.03%]
CRISPR/Cas9基因组编辑技术在微藻代谢工程及功能性食品合成策略中的应用研究进展
Zhiwei Pu,Xue Wang,Yihan Chen et al.
Zhiwei Pu et al.
Microalgae are natural and sustainable biological resources rich in high-value nutrients such as lipids, proteins, and functional pigments, which show great potential in the fields of functional foods, dietary supplements, and natural color...
Methane conversion into methanol by biotechnological processes: Challenges and perspectives [0.03%]
生物技术过程将甲烷转化为甲醇：挑战与展望
Héloïse Baldo,Stéphane Sauvagère,Christian Siatka et al.
Héloïse Baldo et al.
Methane is one of the most prominent greenhouse gases contributing to global warming. It is also a valuable source of energy and a raw material for the production of chemicals. Gas-to-liquid technologies for its conversion into methanol are...
Spatial engineering for biocatalytic cascade control through biomolecular compartmentalization [0.03%]
通过生物分子区隔化对生物催化级联进行空间工程控制
Juntao Ke,Li Wan,Maiqi Chen et al.
Juntao Ke et al.
Spatial engineering has emerged as a transformative paradigm for orchestrating metabolic flux through biomolecular compartmentalization. In cellular systems, the cytosolic dispersion of heterologous enzymes and evolutionary-driven metabolic...
Metabolic engineering strategies for enhanced microbial synthesis of lacto-N-neotetraose: a key acetylated human milk oligosaccharide [0.03%]
增强微生物乳糖-N-新四糖合成的代谢工程策略：一种乙酰化的人类牛奶低聚糖
Shaoru Hu,Shenglong Wang,Ziyi Zhao et al.
Shaoru Hu et al.
Human milk oligosaccharides (HMOs) are complex carbohydrates crucial for infant nutrition, with lacto-N-neotetraose (LNnT) being a key acetylated component that makes up about 10 % of total HMOs. The synthesis of LNnT involves a sequential ...
A review on squalene production by engineered yeasts: Current advances and perspectives [0.03%]
工程酵母角鲨烯生产研究进展与展望
Peng-Cheng Hu,La-Mei Ding,Qiao-Qin Zhao et al.
Peng-Cheng Hu et al.
Squalene, as a natural triterpenoid exhibiting various physiological activities, is primarily extracted from shark liver oil. However, due to the declining shark populations and conservation concerns, the alternative methods for squalene pr...
Integrating multi-omics and artificial intelligence fuels advanced target identification and drug discovery [0.03%]
多组学与人工智能融合推动靶点发现和药物发现创新发展
Hang Chen,Ying Shi,Meiling Yuan et al.
Hang Chen et al.
Target identification is pivotal for developing novel therapeutics in cancer and other diseases. Traditional experiment screening methods are constrained by low throughput and the complexity of biological systems. Multi-omics technologies o...
Morphological regulation of filamentous fungi improves industrial production [0.03%]
丝状真菌形态调控改善工业发酵性能
Qinghua Li,Chen Zhang,Jingwen Zhou et al.
Qinghua Li et al.
Filamentous fungi have emerged as ideal chassis cells for high-value products such as industrial enzymes, therapeutic proteins, and antibiotics, due to their broad substrate adaptability, efficient protein secretion capacity, and well-devel...