Advances in the microbial production of erythritol: From synthetic biological foundations to circular biomanufacturing [0.03%]
以微生生物为基础的赤藓糖醇生产研究：从合成生物学基础到循环生物制造
Yupeng Nie,Jiayuan Liang,Ruiguo Li et al.
Yupeng Nie et al.
Erythritol is a four‑carbon sugar alcohol that is naturally synthesized by various microorganisms as an osmotic pressure protectant. Given its health attributes, such as natural origin and zero calories, the demand for erythritol as a swee...
Multivalent linkers: A growing trend in antibody-drug conjugate development [0.03%]
抗体-药物偶联物开发中多价连接子的发展趋势
Evgeny L Gulyak,Vladimir A Korshun,Ksenia A Sapozhnikova
Evgeny L Gulyak
Over the last 25 years, antibody-drug conjugates (ADCs) have evolved from a novelty to a well-established and clinically validated tool for cancer treatment. Most ADCs are prepared by conjugating one payload per site via linear linkers. How...
Biotechnological advances in key regulatory genes of phenylpropanoid and terpenoid biosynthesis pathways in Panax ginseng: Current insights and future prospects [0.03%]
人参苯丙素和萜类生物合成途径关键调控基因的生物技术进展：当前研究进展与未来展望
Mengyang Zhang,Jia Wu,Jie Zhang et al.
Mengyang Zhang et al.
Background: Panax ginseng, is one of the most important medicinal herbs, widely recognized for its therapeutic value in traditional and modern medicine. Its diverse pharmacological activities are primarily mediated by sec...
Expanding biotechnological applications of Yarrowia lipolytica: Key advances in the past decade [0.03%]
锂平枝胶霉的生物技术应用研究：过去十年的主要进展
Benedict Ryan Lukito,Naazneen Sofeo,Hui Jean Lim et al.
Benedict Ryan Lukito et al.
Yarrowia lipolytica is a non-conventional yeast with innate oleaginous metabolism and unusual tolerance for hydrophobic substrates, positioning it as a prime chassis for waste-enabled precision fermentation. In this review, we consolidate a...
Metabolomics applications in lactic acid bacteria: Identification, classification, and functional analysis [0.03%]
代谢组学在乳酸菌中的应用：识别、分类和功能分析
Lixia Zhao,Wenjun Liu
Lixia Zhao
Background: Lactic acid bacteria (LAB) exhibit a limited correlation between genomic attributes and expressed metabolic traits, with their metabolic profiles being strongly influenced by ecological and environmental condi...
New horizons of nanotechnology-enabled phage therapies for effective management of bacterial infections [0.03%]
基于纳米技术的噬菌体疗法在有效管理细菌感染中的新机遇
Muhammad Babar Malook,Munazza Ijaz,Jiayi Zhang et al.
Muhammad Babar Malook et al.
Bacterial infections continue to persist as a major global healthcare challenge, exacerbated by the alarming rise of antimicrobial resistance (AMR) that renders conventional antibiotics increasingly ineffective. In response, bacteriophage t...
Limitations of traditional mycotoxin control and biotechnological advances toward sustainable solutions [0.03%]
传统霉菌毒素控制的局限性及面向可持续解决方案的生物技术进展
Xitao Wang,Jiansong You,Xiaoyu Li et al.
Xitao Wang et al.
Mycotoxins are harmful fungal metabolites that contaminate food and feed, posing serious health and economic risks worldwide. Traditional control methods often fall short due to inefficiency and safety concerns, prompting the development of...
Recent advances in metabolic engineering of purple non‑sulfur photosynthetic bacteria for enhanced biohydrogen production [0.03%]
用于增强生物制氢的紫硫细菌代谢工程最新进展
Wen Cao,Jiyan Lu,Youmin Jiang et al.
Wen Cao et al.
Photo-fermentative hydrogen production from lignocellulosic biomass offers a sustainable and carbon-neutral route for bioenergy conversion, providing an effective strategy to mitigate fossil resource depletion and greenhouse gas emissions. ...
Surfactants as process intensifiers in lignocellulosic sugar-platform biorefineries: Mechanistic insights and bioprocess implications [0.03%]
surfactants在木质纤维素糖-平台生物精炼厂中的作用及机理和生物过程的影响初探
Xiaoxiao Jiang,Yujie Wang,Zhanyu Wang et al.
Xiaoxiao Jiang et al.
The recalcitrance of lignocellulosic biomass, stemming from its complex cellulose-hemicellulose-lignin matrix, remains the primary techno-economic bottleneck in sugar-platform biorefineries. Surfactants have emerged as versatile process-int...
Comparative evaluation of large language models for biotechnology review writing [0.03%]
生物技术评论写作的大规模语言模型比较评估
Charandatta Muddana,Binbin Wang,Pei-Ti Sun et al.
Charandatta Muddana et al.
Large language models (LLMs) are transforming how biotechnology review articles are conceived and written. This study evaluates LLMs in generating scientific review articles across three case studies with the focus on biomanufacturing and m...