From cell culture to cellular biology in animal-parasitic nematodes: Biotechnological advances [0.03%]
从细胞培养到动物寄生线虫的细胞生物学：生物技术进展
Tao Wang,Robin B Gasser
Tao Wang
Animal-parasitic nematodes are pathogens of medical and veterinary importance, yet their cellular biology remains poorly resolved because complex life cycles, host-dependent development and limited access to particular stages constrain inve...
Site-specific recombinases and their essential role in synthetic biology [0.03%]
位点特异性重组酶及其在合成生物学中的重要作用
Fang Ba,Qing Sun
Fang Ba
Site-specific recombinases, enzymes that bind to specific DNA attachment sites and catalyze DNA rearrangement reactions resulting in permanent and heritable genetic modifications, have emerged as powerful tools in synthetic biology. Their b...
Harnessing machine learning to decode and optimize bioelectrochemical systems: Principles, progress and future directions [0.03%]
利用机器学习解码和优化生物电化学系统：原理、进展与未来方向
Mingyang Liu,Tianru Lou,Yanan Yin et al.
Mingyang Liu et al.
Bioelectrochemical systems (BES) represent an interdisciplinary convergence of biology, electrochemistry, materials science, environmental engineering and mechanical engineering, offering transformative potential for renewable energy genera...
Filamentous bacteriophage M13: Structure, biology, and biotechnological applications [0.03%]
丝状噬菌体M13的结构、生物学特性及其在生物技术中的应用
Paolo Passaretti,Kate Stokes,Jake Carter et al.
Paolo Passaretti et al.
The M13 filamentous bacteriophage has transcended its origins as a model for viral replication to become a premier programmable bio-scaffold at the intersection of nanotechnology, synthetic biology and clinical medicine. While famously know...
Assessing transporter systems of methanogens to boost archaea biotechnology [0.03%]
甲基菌转运系统评估以增强古细菌生物技术
Heta Telimaa,Angus S Hilts,Christian Fink et al.
Heta Telimaa et al.
Methanogenic archaea (methanogens) are key drivers of global carbon cycling and biomethane production, thriving in diverse anaerobic environments through specialized metabolic and transport systems. While methanogenesis is well understood, ...
ε-Poly-l-lysine biomanufacturing advances: From biosynthesis to specification-grade products and applications [0.03%]
聚L-赖氨酸生物制造进展：从生物合成到规格级产品和应用
Daojun Zhu,Shangyu Li,Lei Zheng et al.
Daojun Zhu et al.
ε-Poly-l-lysine (ε-PL) is transitioning from a food preservative to a bio-based cationic functional scaffold with opportunities spanning food, agriculture, and biomaterials. However, progress in the field is hampered by a persistent disco...
Machine learning for precision prediction of antimicrobial peptide activity and spectrum [0.03%]
用于精准预测抗菌肽活性和广度的机器学习方法
Tianxiao Wan,Yiling Wang,Tianle Ren et al.
Tianxiao Wan et al.
The accelerating global crisis of antibiotic resistance demands new therapeutic paradigms, and antimicrobial peptides (AMPs) have emerged as promising candidates owing to their broad activity and reduced propensity for resistance developmen...
CRISPR-based live-cell DNA imaging: Technologies, biological insights and future perspectives [0.03%]
基于CRISPR的活细胞DNA成像：技术、生物学见解和未来展望
Yutong Liu,Lei Feng,Jinming Li et al.
Yutong Liu et al.
Live-cell DNA imaging provides a direct view of genome behavior in real-time and has advanced rapidly with the development of the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas) system. Here,...
Microbial single-cell sequencing technologies: Principles, applications, and spatial integration [0.03%]
微生物单细胞测序技术：原理、应用及空间整合
Fei Xu,Fangyu Mo,Babatunde O Kehinde et al.
Fei Xu et al.
The advent of microbial single-cell sequencing technology provides unprecedented resolution to study microbial ecosystems, revealing cellular heterogeneity, interactions, and genetic evolution of microorganisms. This review systematically c...
Converging quality by design, artificial intelligence, and biofoundry automation: A new paradigm for scalable circular biomanufacturing [0.03%]
质量设计、人工智能和生物工厂自动化相融合：可持续生物制造新模式
Carlos Belloch-Molina,Francisco Vitor Santos da Silva,John P Morrissey et al.
Carlos Belloch-Molina et al.
Synthetic biology applies engineering principles to the rational design of biological systems with the aim of producing predictable and tunable behaviour. Although the field's conceptual foundations and core technologies are well establishe...