Rate control versus rhythm control in atrial fibrillation: lessons learned from clinical trials of atrial fibrillation [0.03%]
心房颤动的节律控制与率控异同点——心房颤动临床试验的经验教训
Albert L Waldo
Albert L Waldo
Ample evidence supports the statement that in patients with atrial fibrillation in whom treatment is warranted, either rhythm control or rate control are acceptable primary therapeutic options. If a rhythm control strategy is chosen, it is ...
Jaya Chandrasekhar,Roxana Mehran
Jaya Chandrasekhar
Heparin has been the principal anticoagulant in the management of ST-elevation myocardial infarction (STEMI) but has several limitations. Although glycoprotein IIb/IIIa inhibitors have been major adjuncts in previous years, in the era of no...
Surgical Revascularization versus Percutaneous Coronary Intervention and Optimal Medical Therapy in Diabetic Patients with Multi-Vessel Coronary Artery Disease [0.03%]
糖尿病多支冠状动脉疾病的外科血运重建与经皮冠状动脉介入及优化药物治疗的比较研究
Gennaro Giustino,George D Dangas
Gennaro Giustino
Coronary artery disease (CAD) is the leading cause of death in patients with diabetes mellitus (DM). Patients with DM and CAD undergoing revascularization with either a surgical or a percutaneous approach are at higher risk of adverse outco...
Long QT syndrome: how effective therapy in a single patient favorably influenced the long-term clinical course and genetic understanding of this hereditary disorder [0.03%]
长QT综合征：单个患者的有效治疗对其长期临床过程和遗传学理解的有利影响
Katherine M Lowengrub,Deborah R Moss,David A Moss et al.
Katherine M Lowengrub et al.
The story of the long QT syndrome involved a chance interaction that took place in 1957 when Dr. Moss was shown a unique series of ECGs with a prolonged QT interval in a young deaf boy whose recurrent syncope culminated in sudden death. Who...
Daniel P Morin,N A Mark Estes rd
Daniel P Morin
Atrial structure and function and its implications for current and emerging treatments for atrial fibrillation [0.03%]
心房结构和功能及其对当前和新兴的房颤治疗的意义
Sandeep Prabhu,Alex J A McLellan,Tomos E Walters et al.
Sandeep Prabhu et al.
Left atrial (LA) structure and function are intimately related to the clinical phenotypes of atrial fibrillation (AF), and have direct implications for the success or otherwise of various therapeutic strategies. In conjunction with intrinsi...
Atrial fibrillation ablation: indications, emerging techniques, and follow-up [0.03%]
房颤消融的指征、新技术及术后管理
Edward P Gerstenfeld,Srikant Duggirala
Edward P Gerstenfeld
Atrial fibrillation (AF) is the most common cardiac arrhythmia and its prevalence is expected to increase as our population ages. The medical management of AF has yielded only modest success, and over the past 15years, catheter ablation (CA...
Tomos E Walters,Andris H Ellims,Jonathan M Kalman
Tomos E Walters
Atrial fibrillation (AF) is the most commonly encountered sustained cardiac rhythm disorder, is an independent risk factor for stroke, heart failure and death, and its development is promoted by a range of common cardiovascular pathologies....
Left atrial appendage closure [0.03%]
左心耳封堵术
Albert C Lin,Bradley P Knight
Albert C Lin
Stroke or systemic embolism is a devastating consequence of atrial fibrillation (AF) due to thrombus formation in the left atrial appendage (LAA). AF causes thrombus formation in the LAA due to both the loss of atrial systole and the unique...
Revascularization vs. Medical Therapy in Stable Ischemic Heart Disease [0.03%]
冠心病血运重建与药物治疗非劣效性的比较研究
Sandra Weiss,William Weintraub
Sandra Weiss
The keynote COURAGE and BARI-2D trials changed the way the interventional community selects patients for revascularization. What we now consider appropriate, especially for percutaneous coronary intervention, has narrowed significantly in s...