Genomics in atrial fibrillation: Predicting recurrence of AF after treatment using genetics [0.03%]
房颤的基因组学:利用基因组学预测房颤治疗后的复发风险
Samuel Harwood,M Benjamin Shoemaker,John Barnard et al.
Samuel Harwood et al.
With the demonstration that AF is highly hereditable and strongly associated with over 100 genetic loci1, one step toward personalized treatment of AF is the potential use of genetic testing to predict response to therapy2-5. Clinical indic...
Leandro Slipczuk
Leandro Slipczuk
Treatment adherence patterns for patients with atherosclerotic cardiovascular disease: Patient and provider perspectives [0.03%]
动脉粥样硬化性心血管病患者治疗依从模式及其医患观点
Mary T Imboden,Kyle G Jones,Sarah E Roth et al.
Mary T Imboden et al.
Background: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of mortality, affecting more than 500 million individuals globally. National guidelines recommend lipid-lowering therapies (LLTs) as first line...
Sudden cardiac arrest: Limitations in risk-stratification and treatment, and the potential for digital technologies and artificial intelligence to improve prediction and outcomes [0.03%]
突发性心脏骤停:风险评估和治疗的局限、以及数字技术及人工智能的应用前景以改善预后
Sudarshan Srivats,Fawzi Zghyer,Zaid Shahrori et al.
Sudarshan Srivats et al.
Sudden cardiac death (SCD) remains a pervasive public health challenge, accounting for a significant proportion of cardiac and all-cause mortality worldwide. Despite notable advancements in cardiovascular therapies and reductions in overall...
Muhammad Shahzeb Khan,Syed Sarmad Javaid,Robert J Mentz et al.
Muhammad Shahzeb Khan et al.
Heart rate variability (HRV) has been reported to predict overall mortality and the risk of cardiovascular disease events in patients, including those with heart failure. However, inconsistent methods of recording and analyzing HRV paramete...
Updates on inherited arrhythmia syndromes (Brugada syndrome, long QT syndrome, CPVT, ARVC) [0.03%]
遗传性心律失常综合征(布鲁加达综合征、长QT综合征、CPVT、ARVC)的最新研究进展
Benjamin M Moore,Thomas M Roston,Zachary Laksman et al.
Benjamin M Moore et al.
The inherited arrhythmia (IA) syndromes are a group of rare and complex conditions that may predispose individuals to ventricular arrhythmias and sudden cardiac death. Our understanding of the genetic architecture underlying these syndromes...
Is it safe to use class 1C antiarrhythmic drugs in patients with coronary artery disease and/or cardiomyopathy? [0.03%]
冠心病和/或心脏衰弱患者可以安全使用第1C类抗心率失常药吗?
Peter G Pantlin,Sahil Bharwani,Mina K Chung et al.
Peter G Pantlin et al.
Class 1C antiarrhythmic drugs (AADs) are a key treatment option for effective rhythm control in several common arrhythmias. Here, we review the relevant background on Class 1C AADs, these drugs' indications and contraindications, and potent...
Effect of inclisiran on lipid and mechanical vascular profiles in familial hypercholesterolemia subjects: results from a single lipid center real-world experience [0.03%]
Inclisiran对家族性高胆固醇血症患者的血脂和血管力学特征影响:来自单个脂质中心真实世界经验的结果
Giosiana Bosco,Francesco Di Giacomo Barbagallo,Maurizio Di Marco et al.
Giosiana Bosco et al.
Background and aims: Familial hypercholesterolemia (FH) is characterized by elevated LDL-C and an increased risk of premature cardiovascular events. Inclisiran is a small interfering RNA that inhibits hepatic PCSK9 synthe...
Pulsed field ablation: The basics relating to effectiveness, durability, and safety [0.03%]
脉冲场消融的基本原理及其有效性、持久性和安全性
Sara Vázquez-Calvo,Deepti Ranganathan,Atul Verma
Sara Vázquez-Calvo
Pulsed field ablation (PFA) represents an innovative energy delivery approach for cardiac arrhythmia treatment, characterized by a favorable safety profile and effective myocardial lesion formation. It has demonstrated high acute pulmonary ...
Atherogenic dyslipidemia and incident cardiovascular events in high-risk hypertension [0.03%]
高危高血压患者脂质异常与心血管事件的关系
Richard Kazibwe,Jeshuah Jehopio,Christopher L Schaich et al.
Richard Kazibwe et al.
Background: Atherogenic dyslipidemia (AD), characterized by low high-density lipoprotein cholesterol (HDL-C) and elevated triglycerides (TG), is associated with increased cardiovascular disease (CVD) risk. This study eval...