Sequential efgartigimod-rituximab therapy in autoimmune nodopathy: A feasibility report on shortening the washout interval for B-cell depletion [0.03%]
序贯Efgartigimod-Rituximab治疗自身免疫性神经节炎：缩短B细胞耗竭洗脱间隔的可行性研究报告
Benjian Sun,Lijia Zou,Jing Li et al.
Benjian Sun et al.
Diseases associated with antibodies targeting nodal-paranodal cell-adhesion molecules have been recognized as a distinct entity termed autoimmune nodopathy (AN) since 2021. Efgartigimod, a neonatal Fc receptor antagonist, may interfere with...
Monoclonal antibody efficacy in seropositive vs seronegative NMOSD: systematic review and meta-analysis [0.03%]
抗原阳性与阴性NMOSD患者中单克隆抗体的有效性：系统回顾和荟萃分析
Khaled Zammar,Abeer Safan,Dareen Jamal Abushalbak et al.
Khaled Zammar et al.
Background and objectives: Monoclonal antibodies have transformed the treatment of neuromyelitis optica spectrum disorder (NMOSD), yet their comparative efficacy by aquaporin-4 immunoglobulin G (AQP4-IgG) serostatus remai...
Association between irritable bowel syndrome and Guillain-Barré syndrome-related immune-mediated peripheral neuropathies: A nationwide cohort study [0.03%]
肠易激综合征与吉兰-巴雷综合征相关自身免疫性周围神经病变的关联：一项全国队列研究
Youngoh Bae,Miyoung Jang,Kwan-Young Bak et al.
Youngoh Bae et al.
Background: Irritable bowel syndrome (IBS) is recognized as a systemic disorder involving gut-brain-immune axis dysregulation, but its long-term association with immune-mediated peripheral neuropathies, including Guillain...
Toward an immunological classification of autism spectrum disorder: A PRISMA-ScR-compliant scoping review [0.03%]
基于免疫学的自闭症谱系障碍分类研究：符合PRISMA-SC标准的综述性研究
Adil Abdul-Rehman Siddiq Al-Salihy
Adil Abdul-Rehman Siddiq Al-Salihy
Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental condition increasingly linked to disturbances in immune signaling and neuroimmune cross-talk. This PRISMA-ScR-guided scoping review synthesizes contemporary evidence to pr...
Brain tumor classification using hybrid spinal-EfficientNet using MRI images [0.03%]
基于MRI图像使用混合脊椎高效网络的脑肿瘤分类
Ponlatha Sambandham,Someswari Perla,Ramachandro Majji et al.
Ponlatha Sambandham et al.
Traditional approaches to brain tumor classification frequently encounter issues such as limited efficiency, class imbalance, and high computational time, which can hinder timely clinical decision-making. To address these challenges, a new ...
Acanthamoeba rhombencephalomyelitis: Novel white matter tract-based neuroinvasive pattern in a retrospective observational study from India [0.03%]
印度后颅窝阿坎théamoeba脑炎的新型白质束侵袭模式：一项回顾性观察研究
Remya Prakash,Aravind Reghukumar,K Rammohan et al.
Remya Prakash et al.
Objective: To describe a distinct rhombencephalomyelitis pattern in patients with central nervous system infection due to free-living amoebae, differing from the classical granulomatous amoebic encephalitis phenotype. ...
Andreea Pleșa,Ion Mărunțelu,Octavian Mihai Sîrbu et al.
Andreea Pleșa et al.
Multiple sclerosis (MS) is an inflammatory demyelinating disorder that affects the central nervous system. Although its exact cause remains unknown, it is known that an autoimmune response, triggered by interactions between genetic predispo...
Immunization with Mycobacterium vaccae attenuates age-associated transcriptional remodeling and microglial reactivity in the rat hippocampus [0.03%]
无害分枝杆菌疫苗菌株免疫可减轻大鼠海马体中年龄相关的转录重构和小胶质细胞反应性
Steven P Guerin,Kevin Sanchez,Arshia Verma et al.
Steven P Guerin et al.
Aging is associated with progressive changes in the neuroimmune environment that increase vulnerability to cognitive decline and neurodegenerative disease. Characteristics of this process like immune cell activation and pro-inflammatory sig...
TGR5 and FXR receptors in motor degeneration: Molecular mechanism, crosstalk pathways and therapeutic prospects [0.03%]
TGR5和FXR受体在运动神经元退行性变中的分子机制、信号交叉对话及治疗前景
Souvik Banerjee,Drishti Panjwani,Shareen Singh et al.
Souvik Banerjee et al.
Motor neuron degeneration in disorders such as amyotrophic lateral sclerosis, spinal muscular atrophy, and Parkinson's disease is increasingly recognized as a consequence of disrupted metabolic, mitochondrial, and inflammatory balance. Ther...