Increased proportion of CD20+ T cells after rituximab treatment in patient with neuromyelitis optica later diagnosed with lung B-cell lymphoma: A case report [0.03%]
利妥昔单抗治疗后CD20+T细胞比例增加的视神经脊髓炎患者随后被诊断为肺B细胞淋巴瘤：个案报告
Jong Kwon Lee,Soonwook Kwon,Jung-Ho Han et al.
Jong Kwon Lee et al.
Introduction: Neuromyelitis optica (NMO) is a rare inflammatory autoimmune disorder of the CNS. Rituximab is used to treat antibody-mediated autoimmune diseases. ...
Anti-GM1 IgM antibody positive axonal variant of Guillain-Barre-syndrome in a pediatric patient with dengue fever [0.03%]
登革热患儿急性吉兰-巴雷综合征(ax-gbs)合并gm1抗体阳性的临床分析
Mario B Prado Jr,Karla M Narito,Karen Joy B Adiao
Mario B Prado Jr
Introduction: While children of all ages may be affected by Guillain-Barre-Syndrome (GBS), there are no reports of Dengue Fever (DF) as the preceding or concurrent infection in this age group. In addition, the presence of...
INFβ treatment affects global DNA methylation in monocytes of patients with multiple sclerosis [0.03%]
INFβ治疗影响多发性硬化患者单核细胞的全局DNA甲基化状态
Susana Nogueira Diniz,Claudia Forlin da Silva,Inara Tais de Almeida et al.
Susana Nogueira Diniz et al.
The combination of genetic and epigenetic influences alters the development of complex diseases. Aberrant patterns of DNA methylation are associated with inflammation and clinical activity in MS. We evaluated the differences between global ...
Tacrolimus as a therapeutic option in patients with acquired neuromyotonia [0.03%]
他克莫司作为获得性神经肌病治疗选择的一项临床研究
Chenchen Liu,Suqiong Ji,Zhuajin Bi et al.
Chenchen Liu et al.
Objective: To analyze the clinical characteristics and outcomes of patients diagnosed with acquired neuromyotonia and who were treated with tacrolimus. Me...
IgG intrathecal synthesis in HIV-associated neurocognitive disorder (HAND) according to the HIV-1 subtypes and pattern of HIV RNA in CNS and plasma compartments [0.03%]
HIV血清型和CNS及血浆间隔区HIV RNA分布对HIV相关神经认知障碍(IHAND)中IgG脑脊液合成的影响
Sergio M De Almeida,Indianara Rotta,Bin Tang et al.
Sergio M De Almeida et al.
We hypothesized that humoral immunity stimulation in the CNS in HIV-1C patients would be lower than that in HIV-1B due to a defective Tat chemokine dimotif (C30C31) that might influence cellular trafficking and CNS inflammation. Sixty-eight...
Steroid-responsive, transverse myelitis is a known complication of COVID-19 [0.03%]
新冠肺炎可导致激素反应型横贯性脊髓炎并发症
J Finsterer
J Finsterer
Central nervous system involvement in adult-onset relapsing hemophagocytic lymphohistiocytosis responsive to maintenance treatment with anakinra [0.03%]
成人起病型复发性噬血细胞综合征中枢神经系统受累利妥昔单抗联合安卡拉治疗有效
Juan Diego Guerra Hiraldo,Ana Domínguez-Mayoral,Francisco Javier García-Gómez et al.
Juan Diego Guerra Hiraldo et al.
A 43 year-old male presented with a relapsing and progressive systemic inflammatory disorder with central nervous system (CNS) involvement. After a two years follow up, he was diagnosed with hemophagocytic lymphohistiocytosis (HLH), based o...
Immunomodulatory and protective effects of interleukin-4 on the neuropathological alterations induced by a potassium channel blocker [0.03%]
钾通道阻滞剂所致神经病理损害的免疫调节和保护作用：Interleukin-4的作用
Nesrine Ahras-Sifi,Fatima Laraba-Djebari
Nesrine Ahras-Sifi
The pathophysiology of neurological diseases related to potassium-channel dysfunction such as epilepsy is increasingly linked to immune system modulation. However, there are limited reports of which interleukin-4 (IL-4) can act on the neuro...
Mills' syndrome: Reporting the disease course with a monthly intravenous immunoglobulin program [0.03%]
Mills综合征：每月一次静脉用免疫球蛋白治疗的作用效果报告
Hussein Algahtani,Bader Shirah,Sarah Algahtani et al.
Hussein Algahtani et al.
Mills' syndrome is an extremely rare, slowly progressive, unilateral ascending or descending clinical syndrome of upper motor neuron-predominant hemiparesis. In this article, we describe a case of a middle-aged woman (initial presentation a...
Refractory NMDA-receptor encephalitis in a teenager: A novel use of Bortezomib [0.03%]
青少年难治性N-甲基-D天冬氨酸受体脑炎的治疗——硼替佐米的新用途
Tuhina Govil-Dalela,Ishita Datta,Mitchel Williams
Tuhina Govil-Dalela
We report the case of a 14-year-old girl who was diagnosed with N-methyl-d-aspartate (NMDA)-receptor encephalitis, with severe features and autonomic instability, requiring intensive care unit admission. She had poor clinical response to th...