Threshold of adequate resection margin for sub-lobar resection in peripheral clinical stage IA1-2 non-small cell lung cancer with tumor spread through air spaces [0.03%]
周围型临床IA1-2期肿瘤伴癌细胞沿肺泡壁内扩散的非小细胞肺癌亚肺叶切除切缘阳性切缘阈值研究
Hanbo Pan,Hui Yin,Wanyu Li et al.
Hanbo Pan et al.
Objectives: Sub-lobar resection (SR) is an established treatment for peripheral clinical stage IA1-2 (cIA1-2) non-small cell lung cancer (NSCLC). However, it may fail to achieve complete resection and is associated with w...
Impact of immune-related and non-immune related hospital admissions on survival of patients with non-small cell lung cancer receiving first-line immunotherapy [0.03%]
免疫相关和非免疫相关住院对接受一线免疫治疗的非小细胞肺癌患者生存影响的研究
Adam Khorasanchi,Mingjia Li,Songzhu Zhao et al.
Adam Khorasanchi et al.
Background: Patients with metastatic non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs) are at risk for severe immune-related adverse events (irAEs). Limited data exists on the association...
Treatment outcomes in patients with stage IV large cell neuroendocrine carcinoma: a nationwide registry study [0.03%]
IV期大细胞神经内分泌癌患者的治疗结局：一项全国登记册研究
Frank W J Heijboer,Jules L Derks,Francien H van Nederveen et al.
Frank W J Heijboer et al.
Introduction: Overall survival (OS) of patients with stage IV large cell neuroendocrine carcinoma (LCNEC) is poor and optimal systemic treatment is unknown. Here, we describe clinical outcomes per treatment strategy of pa...
Higher lung cancer risk among female never-smokers than males in a large married couple study [0.03%]
大型夫妻对照研究中终身不吸烟女性肺癌风险高于男性
Hui Cai,Xiao-Ou Shu,Shenghui Wu et al.
Hui Cai et al.
Background: Whether female being more susceptible to lung cancer among never smokers (LCNS) than males has been a long-standing debate. Method: ...
Immune checkpoint inhibitor-induced interstitial lung disease in non-small cell lung cancer patients with preexisting pulmonary emphysema or interstitial lung abnormalities [0.03%]
自身免疫检查点抑制剂诱导的非小细胞肺癌合并肺气肿或间质性肺病患者的免疫相关性肺炎
Xi Chen,Caijuan Huan,Piao Yang et al.
Xi Chen et al.
Background: Immune checkpoint inhibitor-induced interstitial lung disease (ICI-ILD) is a serious adverse event. While interstitial lung abnormalities (ILA) are known risk factors, the role of preexisting pulmonary emphyse...
First-line immunotherapy ± chemotherapy with or without upfront stereotactic radiotherapy (SRT) in patients with Non-Small cell lung cancer (NSCLC) with asymptomatic brain metastases [0.03%]
一线免疫治疗联合或不联合化疗以及是否进行初始立体定向放射治疗(SRT)在无症状脑转移的非小细胞肺癌(NSCLC)患者中的应用
Lorenz Frehner,Sämi Schär,Stefanie Hayoz et al.
Lorenz Frehner et al.
Background: The role and optimal timing of SRT for patients with advanced NSCLC and asymptomatic brain metastases treated with immune checkpoint inhibitors (ICI) are controversial. ...
Long-term survival comparison of first-line pembrolizumab versus pembrolizumab plus chemotherapy for patients with advanced non-small cell lung cancer: A multicenter propensity-matched cohort study [0.03%]
帕博利珠单抗对比帕博利珠单抗联合化疗一线治疗晚期非小细胞肺癌患者长期生存的多中心倾向性匹配队列研究
Nao Shoshihara,Kinnosuke Matsumoto,Takayuki Shiroyama et al.
Nao Shoshihara et al.
Background: Pembrolizumab is currently used as a first-line therapy for EGFR- and ALK-negative advanced non-small cell lung cancer (NSCLC). However, whether pembrolizumab alone (P-mono) or combined with platinum chemother...
Clinical impact of preoperative adipopenia on postoperative outcomes in non-small cell lung cancer surgery [0.03%]
术前脂肪消耗对非小细胞肺癌术后结果的影响分析
Atsuki Uchibori,Satoru Okada,Masanori Shimomura et al.
Atsuki Uchibori et al.
Background: This study aimed to clarify the relationship between preoperative adipopenia and clinicopathological factors, including sarcopenia and myosteatosis, in patients with surgically resected non-small cell lung can...
A novel agent, p-toluenesulfonamide, in the management of malignant pleural effusions [0.03%]
恶性胸腔积液的新型药物p-托仑磺胺的临床研究
Yung-Hung Luo,Chuan-Ching Yang,Shun-Chi Wu et al.
Yung-Hung Luo et al.
Background: Malignant pleural effusion (MPE) is the lethal consequence of various human cancers metastatic to the pleural cavity, with unclear underlying mechanisms and limited effective treatments. Current therapies, suc...