Clinical impact of local consolidative therapy in EGFR-mutant metastatic NSCLC: A propensity-matched multicenter analysis [0.03%]
表皮生长因子受体突变型转移性非小细胞肺癌局部巩固治疗的临床影响：倾向匹配多中心分析
Eun Hye Lee,Mi-Hyun Kim,Da Hyun Kang et al.
Eun Hye Lee et al.
Objectives: To evaluate the impact of consolidative surgery and radiotherapy (RT) on survival outcomes in patients with advanced or metastatic epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSC...
A dynamic proteomic signature for the prediction of lung Cancer: a longitudinal analysis in the UK Biobank cohort [0.03%]
基于英国生物样本库队列的动态蛋白质组标志物预测肺癌的队列研究
Jie Liang,Yi Feng,Daying Gui et al.
Jie Liang et al.
Background: To understand the molecularly obscure pre-diagnostic phase of lung cancer, we mapped the temporal evolution of the plasma proteome for new biological insights and improved risk prediction. ...
Vebreltinib plus EGFR-TKI for EGFR-mutated NSCLC with MET-driven resistance: A real-world study of Chinese patients [0.03%]
韦比替尼联合EGFT-TKI治疗由MET介导的EGFR突变NSCLC患者的中国真实世界研究
Haibo Wang,Yanyu Cai,Kan Jiang et al.
Haibo Wang et al.
Background: MET amplification/overexpression is a key resistance mechanism to EGFR-tyrosine kinase inhibitors (TKIs) in patients with EGFR-mutated non-small cell lung cancer (NSCLC). However, real-world evidence remains l...
Epidermal growth factor receptor-targeted near-infrared photoimmunotherapy for malignant pleural mesothelioma [0.03%]
表皮生长因子受体近红外光免疫治疗用于恶性胸膜间皮瘤
Miyu Kano,Aki Furusawa,Seiichiro Takao et al.
Miyu Kano et al.
Malignant pleural mesothelioma (MPM) is a rare, aggressive cancer mostly associated with asbestos exposure. Effective treatments are limited, and the prognosis is extremely poor. Therefore, the development of novel therapeutic approaches is...
Prognostic value of serum CYFRA21-1 in locally advanced non-small cell lung cancer undergoing durvalumab consolidation therapy after chemoradiotherapy [0.03%]
德瓦鲁单抗巩固治疗前后局部晚期非小细胞肺癌患者血清CYFRA21-1的预后价值分析
Masahiro Ito,Ryo Ariyasu,Shunsuke Fujishima et al.
Masahiro Ito et al.
Introduction: Chemoradiotherapy (CRT) followed by durvalumab consolidation therapy is the standard treatment for locally advanced non-small cell lung cancer (LA-NSCLC), but robust prognostic biomarkers are lacking. This s...
Clinical outcomes and tumor immune microenvironment in SMARCA4-Deficient NSCLC: A Real-World retrospective study [0.03%]
SMARCA4缺陷型NSCLC的临床预后及肿瘤免疫微环境：一项真实世界回顾性研究
Wencheng Zhao,Maoying Guan,Huixian Zhang et al.
Wencheng Zhao et al.
Background: SMARCA4-deficient thoracic tumors constitute a rare and aggressive form of lung cancer characterized by a dismal prognosis. This research investigates the clinical features, treatment outcomes, and characteris...
Association of tumor CD73 expression with clinical outcomes in small cell lung cancer treated with first-line chemo-immunotherapy [0.03%]
肿瘤CD73表达与小细胞肺癌一线化疗免疫治疗临床结局相关性分析
Masafumi Saiki,Tomohiro Inoue,Kazuho Takusagawa et al.
Masafumi Saiki et al.
Background: Small cell lung cancer (SCLC) is a highly aggressive malignancy with limited therapeutic options. Immune checkpoint inhibitors (ICIs) modestly improve outcomes, but predictive biomarkers are lacking. CD73, an ...
Meta-analysis of cutaneous immune-related adverse events in NSCLC: Accounting for treatment heterogeneity and immortal time bias [0.03%]
免疫相关不良事件的 meta 分析：考虑治疗异质性和永生时间偏倚的影响——基于非小细胞肺癌免疫检查点抑制剂临床试验数据
Lizheng Zhao,Feng Li,Zheqing Zhu et al.
Lizheng Zhao et al.
Background: Previous meta-analyses associate cutaneous immune-related adverse events (cirAEs) with improved survival in non-small cell lung cancer (NSCLC). However, quantifying their actual prognostic benefit is complicat...
Real-world evidence of the impact of guideline concordance on survival in non-small cell lung cancer [0.03%]
肺癌诊疗遵循指南与患者生存关系的实证研究
Thomas Elter,Ursula Marschall,Patrizia Maria Maier et al.
Thomas Elter et al.
Introduction: Outcomes of patients with non-small cell lung cancer (NSCLC) are strongly affected by the level of clinical expertise and specialization. We used insurance claims data to determine real-world guideline-conco...