Model development and feasibility of real-world deployment of multimodal input-based subtyping of depression in tele-counseling for scalable mental health assessment [0.03%]
基于多模态输入的抑郁症亚型分类模型开发及远程心理咨询中的实际应用可行性研究——面向可扩展的心理健康评估
Amal Jude Ashwin Francis,Ahmad Raza,Nischay Patel et al.
Amal Jude Ashwin Francis et al.
The rapid growth of tele-counseling and the use of lay counselors in high-volume, low-resource mental health services has created a need for scalable tools for early detection and triage. Effective personalization now requires stratifying i...
Vyacheslav I Yukalov,Elizaveta P Yukalova
Vyacheslav I Yukalov
Emotions in biological systems are superimposed onto rational actions similarly to colored intrinsic noise superimposed on operationally testable measurements. This idea has recently been developed into a dynamic probabilistic approach. In ...
The behavioural and socio-cognitive implications of the evolution of the primate predatory pattern: An embodied and integrative theory of human carnivory [0.03%]
灵长类捕食行为和社会认知的演化对人类肉食进化的具身整合理论的影响
Luis Gregorio Abad Espinoza
Luis Gregorio Abad Espinoza
The article aims to unravel the elementary structures of hominin carnivory by drawing upon paleoanthropological, archaeological, primatological, and ethnographic investigations to underscore the primary differences and similarities in meat-...
A hydration-scaffold framework for phase-sensitive coupling and collective organization in biomolecular water [0.03%]
生物分子水的相敏感耦合和集体组织的水化支架框架
Pushpendra Singh,Anirban Bandyopadhyay
Pushpendra Singh
We propose a theoretical and computational framework in which ordered hydration layers at biomolecular interfaces act as multi-scale coupled, phase-sensitive degrees of freedom that self-organize biological information processing at all sca...
The noncomputability of immune reaction complexity: Algorithmic information gaps under effective constraints [0.03%]
免疫反应复杂性的非可计算性:有效约束下的算法信息差距
Emmanuel Pio Pastore,Francesco De Rango
Emmanuel Pio Pastore
Adaptive immune responses must turn variable antigenic contexts into valid molecular actions under constraints of recognition, specificity, tolerance, and execution. We study the informational difficulty of this task by representing an inst...
Computational design and experimental validation of fast oligonucleotide-sensing allosteric ribozymes with predefined oligonucleotide binding sites [0.03%]
具有预定小分子rna结合位点的快速寡核苷酸感应别臂核酶的计算设计与实验验证
Dimitrios Kaloudas,Nikolet Pavlova,Robert Penchovsky
Dimitrios Kaloudas
Ribozymes can be engineered to function as molecular switches that exhibit different Boolean logic functions. Here, we describe two novel algorithmic pipelines for the design of YES and NOT Boolean-function oligonucleotide-sensing allosteri...
Way to operationalization of the life process definition 'from purposeful information' resulting from Abel's proposal; mechanisms of evolutionary progress [0.03%]
阿贝尔论生命过程定义“来自目的的信息”的操作化途径以及进化进步的机制
Andrzej Gecow
Andrzej Gecow
This complements my article last year, which proposed two coherent definitions of the life process, with an operationalization of one of them, which gives definition of living object and arose from Abel's article this year. The second, comp...
S Hussain Ather,Richard Gordon
S Hussain Ather
The emergence of the first membranes requires more than the synthesis of amphiphiles; it requires a mechanism that stabilizes bilayer-forming geometries within chemically diverse prebiotic mixtures. We present a minimal thermodynamic model ...
Quantifying quantum-like structure in rough set lattices: Numerical indices for complex and intelligent systems [0.03%]
粗糙集格中量子结构的数量化:复杂数字指标和智能系统的数值指标
Daisuke Uragami,Yukio-Pegio Gunji
Daisuke Uragami
Certain rough set lattices induced by binary relations form almost disjoint unions of Boolean algebras, a subclass of orthomodular lattices that captures quantum-like structure. In empirical data analysis, however, rough set lattices rarely...
A phenomenological multiscale framework for orientational interactions and viscoelasticity in migrating epithelial monolayers [0.03%]
迁移上皮单层中取向相互作用和粘弹性的现象学多尺度框架
Ivana Pajic-Lijakovic,Milan Milivojevic,Peter V E McClintock
Ivana Pajic-Lijakovic
Collective migration of epithelial monolayers emerges from the interplay between mechanical interactions and biochemical signalling on the cellular scale. Here, we provide a phenomenological mechanobiological framework with constitutive int...