Impact of STI and BV co-infection on genital cytokine profiles in postpartum women living with HIV on ART [0.03%]
HIV感染并接受抗病毒治疗的产后妇女同时感染STI和BV对生殖道细胞因子谱的影响
Vani Govender,Dhayendre Moodley,Marothi Letsoalo et al.
Vani Govender et al.
Background: Postpartum women living with HIV are at heightened risk for genital tract infections (GTIs), which may impact mucosal immunity and HIV transmission. We investigated the prevalence of bacterial vaginosis (BV) a...
The function of trophoblast TNFSF13B in unexplained recurrent miscarriage [0.03%]
TNFSF13B在不明原因复发性流产患者滋养细胞功能中的作用研究
Huiping Zhou,Nuray Uskenbayeva,Yang Xu et al.
Huiping Zhou et al.
Trophoblasts, integral to placental function, are pivotal in implantation and in establishing the maternal-fetal interface. Abnormal proliferation and invasion of trophoblasts can significantly contribute to the onset and progression of rec...
Inflammasome-related markers and long non-coding rnas in seminal plasma: Associations with sperm DNA fragmentation and male infertility [0.03%]
精浆中与炎性小体相关的标志物和长链非编码RNA与精子DNA片段化及男性不育的关系
Mohammad Amin Ejehi,Reza Mirfakhraie,Marziyeh Tavalaee et al.
Mohammad Amin Ejehi et al.
Male infertility is increasingly associated with oxidative stress, inflammation, and epigenetic changes. This study examined the relationship between sperm DNA fragmentation (SDF), inflammatory markers in seminal plasma, and long non-coding...
Lactobacillus iners at the nexus of microbiota, immunity, and pregnancy [0.03%]
乳杆菌介入微生物组、免疫和妊娠之間的关系(inertia在这里是中介的意思,指在两个变量之间的中介变量)
Emma L Stemen,Christopher D Radka
Emma L Stemen
Pregnancy induces a dynamic reconfiguration of the vaginal microbiome, typically marked by increased dominance of Lactobacillus species and reduced microbial diversity. Among these bacteria, Lactobacillus iners stands out for its unique gen...
Editorial: Cradle of immunologic breakthroughs: Nurturing reproduction for lifelong discoveries and health, insights from ESRI 2024 [0.03%]
编辑部:免疫学突破的摇篮:ESRI 2024上的终身发现与健康洞察力培育研讨会
Marie-Louise van der Hoorn,Renate G van der Molen,Michael Eikmans
Marie-Louise van der Hoorn
Recurrent pregnancy loss and thyroid autoimmunity: A review of mechanisms and clinical management [0.03%]
反复妊娠丢失与甲状腺自身免疫:机制及临床处理的综述
Yingcui Liang,Zhaorui Wang,Zhuoyao Mai et al.
Yingcui Liang et al.
As a major challenge currently plaguing reproductive medicine, recurrent pregnancy loss(RPL) has a variety of causes. Thyroid autoimmunity(TAI) is a prevalent thyroid disorder among women of childbearing age, potentially impacting maternal ...
Viral orchitis and male infertility: A comprehensive review of pathogenic mechanisms and outcomes [0.03%]
病毒性附睾炎与男性不育:发病机制及转归的全面综述
C Prasanth,A S Vickram,S Bharath et al.
C Prasanth et al.
Male reproductive tract infections and inflammations are recognized as significant aetiological contributors of infertility. Orchitis and epididymo-orchitis caused by systemic or local infection, as well as non-infectious aetiological cause...
Chronic endometritis and reproductive failure: The paradigm shift from microbial eradication to ecological restoration [0.03%]
慢性子宫内膜炎与生殖失败:从微生物清除到生态恢复的范式转变
Xiaojuan Li,Jia Liu,Wensi Yue et al.
Xiaojuan Li et al.
Despite advancements in assisted reproductive technologies, such as preimplantation genetic testing, clinical success rates have plateaued, thereby increasing the clinical focus on the endometrial factor. Chronic endometritis (CE), a persis...
Efficacy of tacrolimus treatment in two-dose single-group controlled trial for patients with refractory infertility [0.03%]
他克莫司治疗难治性不孕症患者二剂量单组序贯对照疗效研究
Michi Hisano,Koji Nakagawa,Masanori Ono et al.
Michi Hisano et al.
In this clinical trial, we aimed to confirm that immunosuppressant tacrolimus could be an effective and safe treatment option for patients with unexplained refractory infertility. Trial participants were women aged between 18 and 40 with re...
Quercetin-3-Glucoside from Ocimum basilicum ameliorates polycystic ovary syndrome by targeting the IL-6/JAK-STAT3 signaling axis [0.03%]
罗勒叶中檞皮素-3-芸香糖苷通过靶向白介素-6/Janus活化激酶-信号转导子和转录激活子3信号轴治疗多囊卵巢综合征
Hina Majid Khan,Imran Tarique,Mohadsa Zainab et al.
Hina Majid Khan et al.
Chronic inflammation is a key contributor to the pathophysiology of polycystic ovary syndrome (PCOS), disrupting hormonal signaling and ovarian function. This study investigated the therapeutic potential of Quercetin-3-Glucoside (Q3G), a bi...