Nana Yang,Meng Li,Jingmei Han et al.
Nana Yang et al.
To elucidate the temporal and dynamic changes in uterine metabolites in mice, uterine samples were collected on Day 2 (D2; n = 8), Day 3 (D3; n = 6), and Day 4 (D4; n = 7) postcoitum and subjected to an untargeted metabolomic analysis. The ...
Comparison of IgG4 and asymmetric IgG and their similar properties as blocking antibodies [0.03%]
IgG4与不对称IgG的比较及其作为阻断型抗体的相似性质
Penghao Li,Yiqun Geng,Xiaomiao Yan et al.
Penghao Li et al.
Background: Blocking antibody can inhibit immunoreactions. IgG4 and asymmetric (asym) IgG are both referred to as "blocking antibodies". However, their working mechanisms and effects on maternal-fetal immune tolerance in ...
Exploring the blood-testis-barrier dynamics by targeting Laminin-α2: ADMET, molecular docking, and dynamics simulation study [0.03%]
针对纤连蛋白-α2靶点探究血睾屏障动力学:药物代谢动力学、分子对接及动态模拟研究
Uddesh Ramesh Wanjari,Abilash Valsala Gopalakrishnan
Uddesh Ramesh Wanjari
Laminin-α2 (LAMA2) is a critical regulatory protein of the blood-testis barrier (BTB), essential for preserving its structural and functional integrity. This study aims to decipher the interaction of LAMA2, BTB-regulating protein with mela...
Chlorogenic acid alleviates letrozole-induced polycystic ovary syndrome in mice by modulating inflammatory mediators and antioxidant signaling pathways [0.03%]
氯ogenic酸通过调节炎症介质和抗氧化信号通路缓解letrozole诱导的小鼠多囊卵巢综合征
Seyed Sobhan Bahreiny,Layasadat Khorsandi,Khojasteh Hoseinynejad et al.
Seyed Sobhan Bahreiny et al.
Polycystic ovary syndrome (PCOS) is a multifaceted endocrine disorder affecting 5-20 % of reproductive-aged women, characterized by hyperandrogenism, ovulatory dysfunction, insulin resistance, and chronic low-grade inflammation. This study ...
Profiling NK cell receptor repertoire of women with idiopathic recurrent pregnancy loss [0.03%]
自然反复流产女性NK细胞受体库特征分析
Aysel Gurbanova,Dorien Feyaerts,Marilen Benner et al.
Aysel Gurbanova et al.
Natural killer (NK) cells have been extensively studied to understand the pathophysiology of idiopathic recurrent pregnancy loss (iRPL), however a clear association between NK cell frequency and iRPL has yet to be established. Most studies ...
Role of maternal immune response and placental exosomes in infant cognitive outcome at 12 months of age [0.03%]
母体免疫反应及胎盘外泌体对婴儿一岁时认知结果的影响作用
Gisele Gouveia,Caroline Camilo,Sergio Nery Simões et al.
Gisele Gouveia et al.
Placental exosomes are released into maternal circulation as key mediators of maternal-fetal crosstalk and act as biomarkers of pregnancy adversities, also influencing the regulation of maternal cytokine levels. However, their role in neuro...
The vaginal microbiome in bacterial vaginosis: Pathogenesis, reproductive impacts, and emerging therapies [0.03%]
细菌性阴道病的阴道微生物组:发病机制、生殖影响和新兴疗法
Eleni Dubé-Zinatelli,Luna Cappelletti,Nafissa Ismail
Eleni Dubé-Zinatelli
Bacterial vaginosis (BV), the leading gynecological condition affecting women of reproductive age globally, is marked by a reduction in the dominant protective bacterial species Lactobacillus within the vaginal microbiome (VMB). This condit...
AT1-AA induced hypertension during pregnancy contributes to developmental programming of hypertension in female offspring [0.03%]
孕期抗甲状腺抗体诱导的高血压对子代女性高血压发病程序的影响
Nathan Campbell,James P Lemon,Melissa Helmich et al.
Nathan Campbell et al.
Preeclampsia (PE), new-onset hypertension during pregnancy, is accompanied by organ dysfunction, in addition to placental dysfunction, and is associated with chronic inflammation and fetal growth restriction. Agonistic autoantibodies agains...
Corrigendum to "Poly(I:C) stimulates cytokine production, but not cell migration, in an extravillous trophoblast cell line" [J. Reprod. Immunol. 171 (2025) 104632] [0.03%]
关于“聚(I:C)刺激细胞系中的细胞因子产生,但不会促进细胞迁移”一文的勘误[J.Reprod.Immunol.171(2025)104632]
B C Hameete,A Hogenkamp,T Plösch et al.
B C Hameete et al.
Published Erratum
Journal of reproductive immunology. 2025 Nov 18:172:104799. DOI:10.1016/j.jri.2025.104799 2025
4,4-Diaponeurosporene regulated lactoferrin expression in neutrophils by IL-27 secreted dendritic cells [0.03%]
4,4-二亚波神经菌素通过树突细胞分泌的白细胞介素-27在中性粒细胞中调控乳铁蛋白表达
Peng Liu,Jinjiao Zuo,Hui Lu et al.
Peng Liu et al.
Sow colostrum is rich in lactoferrin (LF), which can be orally administered to protect piglets from porcine epidemic diarrhea virus (PEDV) infection, thereby reducing piglet mortality. Previous study has shown that sows fed with recombinant...