Testicular immune privilege maintained in incidental testicular microlithiasis: Evidence from 1755 infertile men [0.03%]
偶然发现的睾丸微结石综合征并不破坏免疫赦免：对1755名不育患者的研究证据
Daniele Tienforti,Luca Spagnolo,Giuliana Cordeschi et al.
Daniele Tienforti et al.
Testicular microlithiasis (TM) has been hypothesized to impair testicular immune privilege and promote antisperm antibodies (ASA). We retrospectively evaluated 1755 infertile men who underwent semen analysis and scrotal ultrasound (2001-202...
Interleukin-33 at the maternal-fetal interface: From immune tolerance to obstetric syndromes [0.03%]
蜕膜 interleukin-33：从母胎免疫耐受至妊娠并发症
Tao Liu,Haiqing Huang,Hui Yin
Tao Liu
Successful viviparous reproduction depends on a finely tuned state of maternal-fetal immune tolerance. Among the mediators that shape this balance, the alarmin cytokine interleukin-33 (IL-33) has drawn growing attention as a key regulatory ...
miRNA-mediated control of TLR-NLR interplay in the uterus: A hidden corner of recurrent pregnancy loss [0.03%]
microRNA介导的子宫TLR-NLR互作调控：复发性妊娠丢失研究中的一个隐秘领域
Majid S Jabir,Mahmood Yaseen Mukhlif,Zuhair Mohammed Ali Jeddoa et al.
Majid S Jabir et al.
Toll-like receptors (TLRs) and NOD-like receptors (NLRs) are crucial pattern recognition receptors that initiate inflammatory responses and immunological activation upon detecting pathogen- or damage-associated molecular patterns (PAMPs/DAM...
FTO genotype, thiamine dietary intake, and risk of spontaneous abortion: A case-control study [0.03%]
关于肥胖基因多态性、维生素B1摄入与自然流产的病例对照研究
Elaheh Havaei,Masoomeh Alsadat Mirshafaei,Sheyda Nami et al.
Elaheh Havaei et al.
Background: Spontaneous Abortion (SA) is a prevalent challenge for maternal health. Polymorphism in some genes as well as deficiency of some vitamins can be effective in causing SA. This study aimed to investigate the rel...
Differential expression of ADAM10 in fetal membranes during pregnancy and evaluation as an early blood biomarker for preterm birth [0.03%]
胎膜中ADAM10在妊娠期间的差异表达及其作为早产血浆生物标志物的价值评估研究
Samy Kahouadji,Antoine Puravet,Corinne Belville et al.
Samy Kahouadji et al.
Spontaneous preterm birth (SPTB) includes two distinct presentations: preterm labor with intact membranes (PTL-IM) and preterm premature rupture of membranes (PPROM), both associated with inflammation. In prior work, we identified first-tri...
Bisphenol A as a local immune disruptor in the male reproductive tract [0.03%]
双酚A作为男性生殖道局部免疫干扰物的作用机制研究进展
Amirhossein Aghapour,Rozhina Sabzehban,Sanam Pourazad et al.
Amirhossein Aghapour et al.
Male infertility has become a worldwide concern. Millions of couples today struggle with reproductive problems that result in infertility. While in many cases the underlying cause is unknown, in some cases the problem is with the man. The g...
Maternal endometriosis: An independent risk factor for long-term infectious morbidity of the offspring [0.03%]
母体子宫内膜异位症是子代长期感染性疾病独立的危险因素
Dor Marciano,Gil Gutvirtz,Tamar Wainstock et al.
Dor Marciano et al.
Endometriosis, a debilitating disease characterized by chronic inflammation, might be associated with adverse pregnancy outcomes. However, the long-term health implications for offspring born to mothers with endometriosis remain inadequatel...
Poriferast-5-en-3β-ol improves pelvic inflammatory disease via reducing GADD45A-induced inflammation [0.03%]
Poriferast-5-烯-3β-醇通过减少GADD45A诱导的炎症来改善盆腔炎性疾病
Baoqin Liu,Qing Wang,Junjie Yu et al.
Baoqin Liu et al.
Background: Pelvic inflammatory disease (PID), often triggered by pathogens like Chlamydia, is a major cause of female infertility. This study investigated molecular mechanisms in PID and the therapeutic potential of DanZ...
Lingying Zhang,Ting Wang,Na Zhu et al.
Lingying Zhang et al.
Microbiota exist virtually on every surface of the human body and plays a vital role in maintaining human health. As a significant public health issue, infertility poses a great risk to the physical and mental health of the couple and their...
The efficacy of immunotherapies for pregnancy outcomes of patients with recurrent implantation failure as defined by ESHRE guidelines: A systematic review and network meta-analysis [0.03%]
免疫疗法对复发性植入失败患者妊娠结局疗效的系统评价和网状Meta分析(ESHRE指南定义)
Ying Li,Peixuan Lan,Jing Tang et al.
Ying Li et al.
This study aimed to evaluate the efficacy of immunotherapies for recurrent implantation failure (RIF), as newly defined by ESHRE 2023. We conducted network meta-analyses of randomized trials on immunomodulatory therapies for well-defined RI...