QingShen Granules Activates Mitophagy to Suppress Renal Tubular Epithelial-Mesenchymal Transition via the miR-23b-5p/Nrf2/PINK1 Axis [0.03%]
清神颗粒通过miR-23b-5p/Nrf2/PINK1轴激活线粒体自噬抑制肾小管上皮间质转化
Xu Li,Lan Hu,Qin Hu et al.
Xu Li et al.
Ethnopharmacological relevance: Renal fibrosis (RF) is a pivotal pathological process in chronic kidney disease (CKD), primarily driven by tubular epithelial-mesenchymal transition (EMT). Although Qingshen Granules (QSG) ...
Bupleurum chinense DC. Ameliorates Depression through Hepatic Lipopolysaccharide-Binding Protein-Associated Inflammation and Monoamine Biosynthesis [0.03%]
柴胡通过肝LPS结合蛋白相关炎症和单胺生物合成改善抑郁作用的研究
Yating Zhang,Jiayi Chen,Shaoying He et al.
Yating Zhang et al.
Ethnopharmacological relevance: Bupleurum chinense DC. (Radix Bupleuri, Chaihu) has traditionally been applied to "soothe the liver and relieve depression." Contemporary pharmacological evidence indicates that Radix Buple...
Phenolic fraction of Elsholtzia penduliflora W.W.Sm. ameliorates influenza A virus-induced acute lung injury by inhibiting the IDO-1-mitochondria-STAT1 signaling axis [0.03%]
独活酚性部位通过抑制IDO-1线粒体STAT1信号轴改善甲型流感病毒所致急性肺损伤
Yiting Liu,Shuqi Chen,Jingyan Zhang et al.
Yiting Liu et al.
Ethnopharmacological relevance: Severe influenza is driven by immunometabolic dysregulation, highlighting the need for novel therapeutic strategies. Elsholtzia penduliflora W.W.Sm. (E. penduliflora) is a traditional ethno...
Tibetan Medicine Bawei Chenxiang Wan Attenuates Chronic Mountain Sickness by Targeting the AKT/FOXO3a/CAT axis to Inhibit Oxidative Stress [0.03%]
藏药巴外擦香丸通过靶向Akt/Foxo3a/Cat轴抑制氧化应激来改善慢性高山病
Xiaoya Li,Shujing Zhang,Yuehua Qiu et al.
Xiaoya Li et al.
Ethnopharmacological relevance: Bawei Chenxiang Wan (BWCX) is a classical Tibetan medicinal formula originating from the canonical Tibetan medical text The Four Tantras. It is traditionally used to activate qi circulation...
A Novel Mechanism by which harpagide protects against cerebral ischemia:Focus on Grp75 and MAMs Calcium Homeostasis [0.03%]
哈帕苷通过作用于Grp75及MAMs钙稳态保护缺血性脑卒中的新机制研究
Ke Wang,Yuan-Yuan Dong,Yue Wang et al.
Ke Wang et al.
Ethnopharmacological relevance: Maintenance of Ca2+ homeostasis at endoplasmic reticulum-mitochondria contact sites (MAMs) is a critical determinant of amelioration of post-ischemic brain injury and repair. Harpagide is a...
Corrigendum to "Arjunolic acid from Cyclocarya paliurus ameliorates diabetic retinopathy through AMPK/mTOR/HO-1 regulated autophagy pathway" [J. Ethnopharmacol. 284 (2022) 114772] [0.03%]
correction to "夏枯草 Aristolochic acid from Cyclocarya paliurus ameliorates diabetic retinopathy through AMPK/mTOR/HO-1 regulated autophagy pathway" [J. Ethnopharmacol. 284 (2022) 114772]
Xuan-Xuan Zhang,Ya-Li Ji,Li-Ping Zhu et al.
Xuan-Xuan Zhang et al.
Published Erratum
Journal of ethnopharmacology. 2026 Mar 5:120524. DOI:10.1016/j.jep.2025.120524 2026
Elucidating the anti-HSV-2 mechanism of Longdan Xiegan Decoction via the TLR9 signaling pathway: A multi-omics perspective [0.03%]
基于多组学的龙胆泻肝汤抗HSV-2机制研究-TLR9信号通路视角
Ruoyu Li,Zhixiang Zou,Lin Kuang et al.
Ruoyu Li et al.
Ethnopharmacological relevance: Longdan Xiegan decoction (LDXGT), originally documented in the Secret Collection of the Orchid Chamber, is now widely used in clinical practice. While its clinical efficacy against genital ...
Inhibitory effects and molecular mechanisms of Aristolochic acids on human and rat placental 3β-hydroxysteroid dehydrogenases [0.03%]
Aristolochic酸对人和大鼠胎盘3β-羟基类固醇脱氢酶的抑制作用及分子机制研究
Yuli Yang,Xiya Ren,Chaochao Gong et al.
Yuli Yang et al.
Ethnopharmacological relevance: "Mutong" (commonly known as Akebiae Caulis), historically referring to a group of herbal medicines derived from multiple botanical origins, has been employed in traditional Chinese medicine...
Systems pharmacology reveals the mechanism underlying gastrodiae rhizoma in improving stress-induced cognitive impairment: Protecting hippocampal synapses from excessive microglia-mediated pruning [0.03%]
系统药理学揭示天麻改善应激所致认知障碍的机制:保护海马突触免于小胶质细胞介导的过度修剪作用
Haili Zhang,Ling Li,Zhihuang Zhao et al.
Haili Zhang et al.
Ethnopharmacological relevance: Gastrodiae Rhizoma (GR), the dried tuber of the orchidaceous plant Gastrodia elata Bl., has been utilized in traditional medicine for over two millennia. As a valuable traditional Chinese h...
Babaodan alleviates MAFLD through hepatic glycerophospholipid metabolism and PPARγ/RXRA/GPAT3 based on spatial metabolomics and proteomics analysis [0.03%]
基于空间代谢组学和蛋白质组学的巴邦丹通过肝脏甘油磷脂代谢和PPARγ/RXRA/GPAT3缓解MAFLD
Shi Qiu,Zhicheng Lai,Zhibo Wang et al.
Shi Qiu et al.
Ethnopharmacological relevance: Babaodan (BBD), a traditional Chinese medicine formula with a history of clinical use, has been extensively applied in the treatment of various hepatic disorders, but its multi-target mecha...