Gentiopicroside activates PINK1-dependent mitophagy to inhibit ferroptosis and promote flap survival [0.03%]
姜黄素茋通过激活PINK1依赖性线粒体自噬抑制铁死亡并促进皮肤创面愈合
Hebin Pan,Kaitao Wang,An Wang et al.
Hebin Pan et al.
Ethnopharmacological relevance: Distal necrosis remains a major challenge in reconstructive flap surgery due to ischemia-reperfusion injury. Gentiana manshurica Kitagawa (Longdan), traditionally used to clear heat and dam...
Pharmacological activities of hydroethanolic extract from Harrisia adscendens (Gürke) Britton & Rose cladodes: Antinociceptive, anti-inflammatory, antipyretic, and wound healing effects [0.03%]
Harrisia adscendens（Gürke）Britton＆Rose茎节的 hydroethanolic提取物的药理活性：抗疼痛，抗炎，解热和伤口愈合作用
Anderson Felipe Soares de Freitas,Suéllen Pedrosa da Silva,Cláudia Bernadete de Souza Lira et al.
Anderson Felipe Soares de Freitas et al.
Ethnopharmacological relevance: Harrisia adscendens (Gürke) Britton & Rose is traditionally used to manage kidney problems, fever, and pain. Despite its traditional use, its pharmacological properties remain underexplore...
Application of Microorganisms in Fermented Traditional Chinese Medicine: A Review [0.03%]
发酵中药领域益生菌的应用及展望——兼论汉方药代研究中的肠道菌群效应
Yayuan Li,Xuanqi Ke,Zixuan Shu et al.
Yayuan Li et al.
Ethnopharmacological relevance: Microbial fermentation is an indispensable processing technology in traditional Chinese medicine (TCM). This technology uses functional microorganisms to transform bioactive components, add...
Beyond HbS polymerization inhibition: Antioxidant and anti-hemolytic actions of two varieties of Vigna sesquipedalis (L.) F.Agcaoili in sickle cell disease [0.03%]
基于刀豆属多年生草本植物的海蒂黑刀豆和长荚刀豆在抗镰状细胞病方面的抗氧化及抗溶血作用研究超出HbS聚合抑制的作用范畴
Eleazar Chukwuemeka Anorue,Victor Duniya Sheneni
Eleazar Chukwuemeka Anorue
Ethnopharmacological relevance: Polymerization is a major pathological feature of sickle cell disease (SCD). Although conventional therapies reduce disease severity, their use is limited by adverse effects, high cost, and...
Multi-omics analysis reveals Yishen Qutong formula promotes ferroptosis in Lewis lung cancer associated with Keap1/Nrf2/Nqo1 pathway modulation [0.03%]
多组学分析揭示益肾祛肿瘤公式通过调控Keap1/Nrf2/Nqo1通路促进Lewis肺癌细胞铁死亡
Sicong Li,Yiyuan Cui,Sujuan Zheng et al.
Sicong Li et al.
Ethnopharmacological relevance: Yishen Qutong Formula(YSQTF) is composed of six ingredients of Liuwei Dihuang, a classical traditional Chinese medicine fomula, plus Drynaria fortunei (Kunze) J. Sm., Bombyx Batryticatus, H...
Kaiyujiangzhuo formula alleviates glycolipid metabolic disorders by improving arginine metabolism and inhibiting the Erk-mediated PPARγ-Ser273 phosphorylation [0.03%]
解糖脂代谢紊乱方 Kaiyujiangzhuo 方通过改善精氨酸代谢及抑制 Erk 介导的 PPARγ-Ser273 磷酸化发挥作用
Yuqing Shi,Zepeng Zhang,Haining Lin et al.
Yuqing Shi et al.
Ethnopharmacological relevance: Kaiyujiangzhuo formula (KYJZ) is an optimized herbal formulation derived from the classical prescription "Dahuang Huanglian Xiexin decoction," recorded in the ancient Chinese monograph Shan...
Swertia chirayita ameliorates MAFLD by improving intestinal microenvironment and hepatic lipogenesis [0.03%]
袁柏仁改善肠道微环境和肝脂生成从而缓解MAFLD
Xiaoling Gou,Yihong Shen,Fenglian Liu et al.
Xiaoling Gou et al.
Ethnopharmacological relevance: Metabolic-associated fatty liver disease (MAFLD) is emerging as a very serious threat to human health. The search for effective remedies for MAFLD from natural herbs is gaining increasing a...
Study on Chronic Toxicity, Metabolic Profiles and Potential Mechanisms of Aristolochiae Fructus in Rats [0.03%]
关木通的慢性毒性和代谢调控作用及机制研究
Haisheng Yuan,Fang Wang,Yan Yi et al.
Haisheng Yuan et al.
Ethnopharmacological relevance: Aristolochiae Fructus (AF) is a "notable" Traditional Chinese Medicines (TCM), renowned for its efficacy in clearing lung heat, descending qi, relieving cough and asthma, as well as its wel...
Ethnopharmacological relevance and anti-inflammatory mechanisms of Lycopi Herba in diabetic nephropathy: Integrated chemical profiling and pharmacological evaluation [0.03%]
基于药理和化学评价的淫羊藿在糖尿病肾病中的民族药理学相关性和抗炎机制研究
Lu-Zhou Chen,Shuai Yang,Dong-Mei Ren et al.
Lu-Zhou Chen et al.
Ethnopharmacological relevance: Lycopi Herba is a traditional Chinese medicine with blood-activating and stasis-resolving properties, traditionally prescribed to promote diuresis and alleviate edema. These traditional ind...
Mechanism of Shenqi Citian Granules in the Treatment of Acute Mountain Sickness Based on Proteomics and Serum Pharmacochemistry [0.03%]
基于蛋白质组及血清药物化学的参芪茨仁颗粒治疗急性高原病作用机理研究
Zongyuan Li,Zhixin Sun,Jianhui Sun et al.
Zongyuan Li et al.
Ethnopharmacological relevance: Shenqi Citian Granules (SQCT), a traditional Chinese medicine compound formula derived from Tibetan medical empirical knowledge, is composed of 15 medicinal materials including the Tibetan ...