Exploring the intervention mechanism of Acori Tatarinowii Rhizoma-Polygalae Radix herb pair on post-stroke depression based on multi-omics analysis [0.03%]
基于多组学分析的石菖蒲-远志药对干预缺血卒中后抑郁的作用机制探讨
Yansai Zhao,Wei Hong,Ying Chen et al.
Yansai Zhao et al.
Ethnopharmacological relevance: The herb pair of Acori Tatarinowii Rhizoma (Shi Chang Pu) and Polygalae Radix (Yuan Zhi) is a classic combination in Traditional Chinese Medicine for "opening the orifices to revive the min...
Dendrobine ameliorates non-alcoholic fatty liver disease by inhibiting mitochondrial fission through modulation of the Wnt5a/p-CaMKII/p-Drp1 signaling axis [0.03%]
藤黄素通过调节Wnt5a/p-CaMKII/p-Drp1信号轴抑制线粒体分裂从而改善非酒精性脂肪肝病
Xiaolong Fu,Shiyi Gou,Leiqin Shi et al.
Xiaolong Fu et al.
Ethnopharmacological relevance: Dendrobium nobile Lindl. (DNL) is a precious traditional Chinese herbal medicine with a variety of bioactive substances, which is recorded in the Chinese Pharmacopoeia (2025 edition). Conte...
Efficacy and safety of medicine-food homology Shenqi paste in older adults with diabetic sarcopenia: A randomized, double-blind, placebo-controlled trial [0.03%]
补肾药食同源膏方治疗糖尿病肌少症老年人的疗效及安全性：随机双盲安慰剂对照试验
Lijiangshan Hua,Yunchao Wang,Xiao Yuan et al.
Lijiangshan Hua et al.
Ethnopharmacological relevance: Diabetic sarcopenia (DS), an emerging diabetes complication, poses an increasing challenge to the elderly population. Shenqi paste (SQP) consists of 8 medicine-food homology substances: Ast...
An integrative analysis combining network pharmacology, transcriptomics, and experimental validation of the Tibetan medicine Renqing Changjue in gastric ulcer protection [0.03%]
基于网络药理学、转录组学和实验验证的藏药日晒常厥保护胃溃疡的整合分析研究
Guang Yue,Yuan Chen,Yanjun Liu et al.
Guang Yue et al.
Ethnopharmacological relevance: Renqing Changjue (RQCJ), a time-honored Tibetan prescription, has long been used to treat "heat toxin"-related disorders, particularly those affecting the digestive system. Despite its exte...
The co-action mechanism of agreement prescription "homotherapy for heteropathy" against esophageal, head and neck cancer, and lung cancer: network pharmacology, bioinformatics analysis, and experimental validation [0.03%]
同病异治协定处方抗食管癌、头颈癌和肺癌的协同作用机制：网络药理学、生物信息学分析与实验验证
Yanwei Li,Shuang Li,Yang Li et al.
Yanwei Li et al.
Background: "Homotherapy for heteropathy" represents a distinctive therapeutic strategy informed by Traditional Chinese Medicine (TCM) principles. This study aims to explore the common targets and molecular mechanisms of ...
Eupalinolide B ameliorates liver fibrosis by targeting PKCα to suppress the AKT/mTOR axis in hepatic stellate cells [0.03%]
Eupalinolide B通过靶向PKCα抑制肝星状细胞AKT/mTOR轴治疗肝纤维化
Ao Wang,Hui Dong,Yaqian Cui et al.
Ao Wang et al.
Ethnopharmacological relevance: Eupatorium lindleyanum DC. (Asteraceae), traditionally known as "Yemazhui," is a renowned herbal medicine historically used for heat-clearing, detoxification, and resolving phlegm-propertie...
ShenRongGuBenHuanShao Pill ameliorates oligoasthenospermia by alleviating oxidative stress and DNA damage via activation of the PI3K/Akt/mTOR pathway [0.03%]
神茸固本丸通过激活PI3K/AKT/mTOR信号通路改善生精功能障碍所致少弱精子症及氧化应激和DNA损伤
Yazhou Shao,Yanan Meng,Yichen Jing et al.
Yazhou Shao et al.
Ethnopharmacological relevance: ShenRongGuBenHuanShao Pill (SRGBHSP) is a classic kidney-tonifying traditional Chinese medicine formula with a clinical history of nearly a century for treating oligoasthenospermia (OA). Ho...
Targeting hypoxia: the role of ethanolic extract of Coptis chinensis Franch. in modulating HIF-1α/IL-17 axis in oropharyngeal candidiasis [0.03%]
针对缺氧：黄连乙醇提取物在调节口咽念珠菌病中HIF-1α/IL-17轴的作用
Ran Xu,Yujie Chen,Yue Yang et al.
Ran Xu et al.
Ethnopharmacological relevance: Oropharyngeal candidiasis (OPC), primarily induced by Candida albicans, poses a significant threat to oral health due to the hypoxic microenvironment established by C. albicans biofilms. Co...
Antiplasmodial and antioxidant constituents from the stem bark of Haematostaphis barteri Hook.f. (Anacardiaceae): isolation and bioactivity evaluation [0.03%]
抗疟和抗氧化成分从金砂枣的树皮中分离及其生物活性评估
Dé Ndonaï-Koula Lafya Bodeboret Djimtoingar,Jean Noël Nyemb,Hervé Landry Ketsemen et al.
Dé Ndonaï-Koula Lafya Bodeboret Djimtoingar et al.
Ethnopharmacological relevance: Haematostaphis barteri Hook.f. (Anacardiaceae) is widely used in African traditional medicine for the management of malaria and other ailments. However, its active antiplasmodial constituen...
Shiwei Hezi Pill alleviates cisplatin-induced acute kidney injury through integrative network pharmacology, transcriptomics and experimental validation [0.03%]
石韦合剂通过整合网络药理学、转录组学及实验验证改善顺铂致急性肾损伤
Ge Jiang,Guang Yue,Zhenhua Guo et al.
Ge Jiang et al.
Ethnopharmacological relevance: Shiwei Hezi Pill (SHP) is a classical Tibetan polyherbal remedy traditionally used to treat nephritis and urinary tract disorders. It is known in Tibetan medicine for its effects in clearin...