Ex vivo calcium imaging of sympathetic neurons in intact mouse stellate ganglia [0.03%]
完好的小鼠stellate神经节的离体钙成像技术及其在交感神经元中的应用
Arianna Scalco,Nathan Balthazor,Beth A Habecker
Arianna Scalco
Sympathetic hyperactivity is a common feature of cardiovascular diseases including hypertension, and sympathetic neurons are hyperactive after a week of angiotensin II (AngII) hypertension. Nerve firing increases intracellular Ca2+ and we w...
From discovery to debate: The history of menopausal hormone therapy and its impact on cardiovascular health [0.03%]
从发现到争论：绝经期激素治疗的历史及其对心血管健康的影响
Allyson I Schwab,Virginia R Nuckols,Katherine Haigh et al.
Allyson I Schwab et al.
Cardiovascular disease (CVD) continues to be the leading cause of death in women. Menopause is associated with a variety of physiological changes, including hallmark vasomotor symptoms and an increased risk of CVD. Traditional hormone thera...
Reduced resting beat-to-beat blood pressure variability in patients with Parkinson's disease [0.03%]
帕金森病患者的静息心搏间血压变异性降低
Rosa V D Guerrero,Jeann L Sabino-Carvalho,Pedro R P Brandão et al.
Rosa V D Guerrero et al.
Purpose: Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects both motor and non-motor functions, including autonomic regulation. In the cardiovascular system, autonomic dysfunction may result...
Inspiratory muscle training enhances cardiac autonomic response to orthostatic stress in patients with Parkinson's disease: a preliminary study [0.03%]
inspiratory肌肉训练可改善帕金森病患者的直立位自主神经反应：一项初步研究
Felipe Castro Ferreira,Michelle Cristina Salabert Vaz Padilha,Pedro Paulo da Silva Soares et al.
Felipe Castro Ferreira et al.
In this pilot study, eight patients with Parkinson's disease (PD) and eight age-matched healthy controls completed a 5-week home-based inspiratory muscle training (IMT) program. Maximal inspiratory pressure and heart rate variability during...
Exercise and the autonomic nervous system: New insights and future directions [0.03%]
自主神经系统的运动反应及其机制研究的新视角
James P Fisher,Lauro C Vianna
James P Fisher
Symmetric projection attractor reconstruction: Transcutaneous auricular vagus nerve stimulation for visually induced motion sickness [0.03%]
对视觉诱发运动病的耳迷走神经透皮刺激的对称投影吸引子重建分析
Emmanuel Molefi,Ian McLoughlin,Ramaswamy Palaniappan
Emmanuel Molefi
Motion sickness is an enigma that has plagued humans for millennia - and could be exacerbated by automated vehicles and virtual reality. Here, we examined the neuromodulatory effects of transcutaneous auricular vagus nerve stimulation (taVN...
Microneedle-assisted iontophoretic transdermal administration of adrenergic antagonists does not modulate palmar sweating induced by static exercise in healthy young adults [0.03%]
微针辅助离子透皮给药肾上腺素受体拮抗剂无法调节健康年轻人静态运动诱发的手掌出汗反应
Hui Wang,Kaito Tamura,Shoma Oshima et al.
Hui Wang et al.
Palmar sweating is primarily evoked by psychological and physical (e.g., exercise) stress, while the peripheral control of this response remains uncertain. We investigated whether the transdermal administration of adrenergic antagonists mod...
Crosstalk between bladder-cardiovascular autonomic nervous system in synucleinopathies [0.03%]
路易 bodies疾病患者的膀胱和心血管自主神经系统的相互作用
Ryuji Sakakibara,Tomoyuki Uchiyama,Tatsuya Yamamoto
Ryuji Sakakibara
Objective: Parkinson's disease (PD) and multiple system atrophy (MSA) are major neurogenerative diseases characterized pathologically by abnormal alpha-synuclein aggregation, called synucleinopathy. PD and MSA are clinica...
Sacral nerve electrical stimulation (SNES) ameliorates bladder dysfunction and detrusor fibrosis in early-stage spinal cord injury: A randomized controlled experimental study in rats [0.03%]
腰骶神经电刺激改善脊髓损伤早期膀胱功能障碍及逼尿肌纤维化：大鼠随机对照实验研究
Lingyan Wang,Junhua Li,Chenhao Tang et al.
Lingyan Wang et al.
This study evaluated the therapeutic effects of sacral nerve electrical stimulation (SNES) targeting the L6-S1 spinal nerves on neurogenic bladder dysfunction following spinal cord injury (SCI). Using a randomized controlled design, 80 fema...
Mechanisms underpinning peripheral chemoreceptor modulation of hypertension [0.03%]
外周化学感受器在高血压调节中的作用机制
Xin Shen,Julian F R Paton
Xin Shen
On its activation, the carotid body (CB) provides one of the greatest stimulants to raise cardiovascular sympathetic activity. Through proof of principle studies the CB has been shown to be a major driver of the heightened sympathetic activ...