Primary prophylaxis of seizures in post-hemorrhagic stroke rehabilitation patients [0.03%]
出血性卒中康复患者的原发性癫痫预防
Valeria Pingue,Diego Franciotta
Valeria Pingue
Background and purpose: Prophylactic use of antiseizure medications (ASMs) for optimal management of post-hemorragic stroke (HS) seizures remains controversial. We retrospectively evaluated the influence of seizures on fu...
Siyuan Chen,Madison Crago,Alain Lekoubou
Siyuan Chen
Background: Observational studies have established a relationship between stroke and epilepsy. While most studies have reported an increased risk of epilepsy following a stroke, fewer have concluded that a diagnosis of ep...
Can Ozlu,Emily M Spelbrink,Tanya L Brown et al.
Can Ozlu et al.
The SLC13A5 gene encodes a sodium citrate co-transporter, with loss of function variants causing autosomal recessive developmental and epileptic encephalopathy 25, DEE25. DEE25 is an ultra-rare genetic disorder, known to cause neonatal onse...
4-Phenylbutyrate rescues neurobehavioral phenotypes in SLC6A1-related encephalopathy [0.03%]
4-苯基丁酸盐可治疗SLC6A1相关性脑病的神经行为表型
Karishma Randhave,Kirill Zavalin,Jing-Qiong Kang
Karishma Randhave
Developmental and epileptic encephalopathies (DEEs) caused by pathogenic variants in SLC6A1, encoding γ-aminobutyric acid (GABA) transporter 1 (GAT-1), present with seizures and severe comorbidities including cognitive impairment, developm...
Elevated thalamic blood flow in self-limited epilepsy with centrotemporal spikes [0.03%]
中央中颞棘波自限性癫痫患者丘脑区血流增高
Niki Iasinovschi,Elizabeth Tong,Lucia Bicknell et al.
Niki Iasinovschi et al.
Children with self-limited epilepsy syndrome with centrotemporal spikes (SeLECTS) exhibit altered thalamocortical connectivity, but whether thalamic function itself is abnormal remains unclear. We investigated whether thalamic blood flow, a...
Evaluating the impact of cenobamate in the management in patients with drug resistant focal epilepsy - A retrospective real world observational study of patients attending NHS Greater Glasgow and Clyde [0.03%]
评估cenobamate在难治性局灶性癫痫患者管理中的影响-一项苏格兰国民卫生服务（NHS）克莱德地区患者的回顾性真实世界观察研究
M Taha,L Stephen,S Nichol et al.
M Taha et al.
Introduction: Cenobamate (CNB) is the latest ASM to be licensed in the UK as an adjunctive treatment for adults with focal epilepsy. Early clinical trials have been encouraging with up to 50.4 % of patients showing a 50 %...
The SEEG brain network predicts epileptic surgical outcomes of radiofrequency thermocoagulation [0.03%]
基于SEEG的脑网络预测射频热凝术治疗难治性癫痫手术预后价值
Jingxian Shen,Hongping Tan,Bocheng Wu et al.
Jingxian Shen et al.
Predicting the postoperative outcome of stereoelectroencephalography-guided radiofrequency thermocoagulation (SEEG-guided RF-TC) remains challenging despite its increasing use in epilepsy treatment. Although SEEG-guided RF-TC has attracted ...
Antiseizure medication effects on the autonomic nervous system in pediatric patients with epilepsy [0.03%]
抗癫痫药物对儿童癫痫患者自主神经系统的的影响
Fatemeh Mohammad Alizadeh Chafjiri,Stephanie Dailey,Saeid Sadeghian et al.
Fatemeh Mohammad Alizadeh Chafjiri et al.
Patients with epilepsy (PWE) taking antiseizure medications (ASMs) exhibit altered autonomic nervous system (ANS) parameters. ANS signals may monitor ASM applications and effectiveness non-invasively. Due to limited research, we reviewed th...
Time-dependent risk of stroke following epilepsy: A nationwide cohort study in South Korea [0.03%]
癫痫后卒中发生的时间依赖性风险——一项韩国全国队列研究
Seung Won Lee,Yejin Lee,Chaeyoon Kang et al.
Seung Won Lee et al.
Background: Epilepsy(ICD-10 G40-G41) and stroke-including hemorrhagic stroke (HS: I60-I62) and ischemic stroke (IS: I63))-are major neurological disorders. Although epilepsy has been proposed as a risk factor for stroke, ...
Hippocampal, fornix, and mammillary body atrophy in patients with mesial temporal sclerosis [0.03%]
内侧颞叶硬化患者的海马、穹窿和乳头体萎缩
Mia Mojica,Hannah Fleming,Timo Krings et al.
Mia Mojica et al.
This study investigates structural changes in the hippocampus, fornix, and mammillary bodies in patients with mesial temporal sclerosis (MTS), examining their relationship to clinical characteristics and association with memory performance....