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期刊名:Mechanisms of development

缩写:MECH DEVELOP

ISSN:0925-4773

e-ISSN:1872-6356

IF/分区:0.0/Q2

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共收录本刊相关文章索引671
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Fernanda M Bizotto,Renan S Ceratti,Antonio S K Braz et al. Fernanda M Bizotto et al.
Change in cell morphogenesis is an important feature for proper development of eukaryotes. It is necessary for cell polarity and asymmetry and is essential for asymmetric cell division. RAM/MOR is a conserved signaling network that coordina...
Junpei Kuroda,Atsuko H Iwane,Shigeru Kondo Junpei Kuroda
The embryonic fins and the tip of adult fins of teleost fish are supported by rows of straight, unmineralized fibrils called actinotrichia. The proximal ends of the actinotrichia are bundled and the mineralized bones called lepidotrichia ar...
Skyler Berardi,Alanna McFall,Amanda Toledo-Hernandez et al. Skyler Berardi et al.
Germline stem cells are maintained in the distal region of the C. elegans gonad. These cells undergo mitotic divisions, and GLP-1/Notch signaling dictates whether they remain in this state. The somatic distal tip cell (DTC) caps the end of ...
Catalina Casillas,Henk Roelink Catalina Casillas
Sonic Hedgehog (Shh) signaling is characterized by non-cell autonomy; cells expressing Shh do not respond to the ligand. Here, we identify several Shh mutations that can activate the Hedgehog (Hh) pathway cell-autonomously. Cell-autonomous ...
Ricardo Fuentes,Joaquín Letelier,Benjamin Tajer et al. Ricardo Fuentes et al.
Understanding how the genome instructs the phenotypic characteristics of an organism is one of the major scientific endeavors of our time. Advances in genetics have progressively deciphered the inheritance, identity and biological relevance...
Nikhita Pasnuri,Purnati Khuntia,Aprotim Mazumder Nikhita Pasnuri
Single molecule Fluorescence in situ Hybridization (smFISH) for mRNA provides a powerful quantitative handle on expression from endogenous gene loci. While the method has been widely applied in cells in culture, applications to primary tiss...
Rodolfo Martín-Del-Campo,Annelisse Bárcenas-Ibarra,Itzel Sifuentes-Romero et al. Rodolfo Martín-Del-Campo et al.
Normal development involves the interplay of genetic and epigenetic regulatory mechanisms. Pax6 is an eye-selector factor responsible for initiating the regulatory cascade for the development of the eyes. For the olive ridley sea turtle (Le...
Sandra Sofía Edwards,María Graciela Delgado,Guilherme Pedreira de Freitas Nader et al. Sandra Sofía Edwards et al.
Thanks to the power of Drosophila genetics, this animal model has been a precious tool for scientists to uncover key processes associated to innate immunity. The fly immune system relies on a population of macrophage-like cells, also referr...
Warren A Vieira,Kaylee M Wells,Roni Milgrom et al. Warren A Vieira et al.
Urodele amphibians such as the axolotl regenerate complete limbs as adults, and understanding how the "blueprint", or pattern, of the regenerate is established and manipulated are areas of intense interest. Nutrient signaling plays an impor...
Santiago Cerrizuela,Guillermo A Vega-López,María Belén Palacio et al. Santiago Cerrizuela et al.
The neural crest (NC) is a multipotent migratory embryonic population that is formed during late gastrulation and gives rise to a wide array of derivatives, including cells from the peripheral nervous system (PNS), the craniofacial bones an...