Huibert F van Waegeningh,Fenna A Ebbens,Erik van Spronsen et al.
Huibert F van Waegeningh et al.
Objective: The epithelium lining the human middle ear and adjacent temporal bone cavity shows a varying morphological appearance throughout these cavities. Its embryologic origin has long been debated and recently got att...
The microRNA-306/abrupt regulatory axis controls wing and haltere growth in Drosophila [0.03%]
微小核糖核酸306和abrupt调节子轴调控果蝇翅和卤角的生长
Carolina J Simoes da Silva,Ismael Sospedra,Ricardo Aparicio et al.
Carolina J Simoes da Silva et al.
Growth control relies on extrinsic and intrinsic mechanisms that regulate and coordinate the size and pattern of organisms. This control is crucial for a homeostatic development and healthy physiology. The gene networks acting in this proce...
The transcription factor Foxp1 regulates the differentiation and function of dendritic cells [0.03%]
转录因子Foxp1调控树突状细胞的分化和功能
Ziyi Guo,Yijie Tao,Shulei Yin et al.
Ziyi Guo et al.
Dendritic cells (DCs) are the sentinels of the immune system and play a critical role in initiating adaptive immune responses against pathogens. As the most powerful antigen presenting cells, DCs are also important in maintaining immune hom...
High temperature limits on developmental canalization in the ascidian Ciona intestinalis [0.03%]
高温对海鞘Ciona intestinalis发育可塑性的限制
Steven Q Irvine,Katherine B McNulty,Evelyn M Siler et al.
Steven Q Irvine et al.
The normal embryogenesis of marine animals is typically confined to a species-specific range of temperatures. Within that temperature range development results in a consistent, or canalized, phenotype, whereas above and below the range abno...
Kevin D Thiessen,Steven J Grzegorski,Yvonne Chin et al.
Kevin D Thiessen et al.
Deflecting biomineralized crystals attached to vestibular hair cells are necessary for maintaining balance. Zebrafish (Danio rerio) are useful organisms to study these biomineralized crystals called otoliths, as many required genes are homo...
Jacopo P Mortola
Jacopo P Mortola
Whether the growth of embryos after a period of stunt becomes accelerated (Catch-Up Growth, CUGr), as it occurs postnatally, has rarely been examined experimentally in any class of animals. Here, hypoxia or cold of different degrees and dur...
Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway [0.03%]
Nagk和UDP-GlcNAc补救途径对Wnt信号的发育调控
Leif R Neitzel,Zachary T Spencer,Anmada Nayak et al.
Leif R Neitzel et al.
In a screen for human kinases that regulate Xenopus laevis embryogenesis, we identified Nagk and other components of the UDP-GlcNAc glycosylation salvage pathway as regulators of anteroposterior patterning and Wnt signaling. We find that th...
Synchronization of Hes1 oscillations coordinates and refines condensation formation and patterning of the avian limb skeleton [0.03%]
Hes1振荡的同步协调并精确化鸟类肢骨凝集的形成和模式化
Ramray Bhat,Tilmann Glimm,Marta Linde-Medina et al.
Ramray Bhat et al.
The tetrapod appendicular skeleton is initiated as spatially patterned mesenchymal condensations. The size and spacing of these condensations in avian limb buds are mediated by a reaction-diffusion-adhesion network consisting of galectins G...
Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development [0.03%]
血流动力学作用能促使血管平滑肌细胞在小鼠胚胎发育过程中募集至血管壁中
Rachel L Padget,Shilpa S Mohite,Tanner G Hoog et al.
Rachel L Padget et al.
Blood vessel maturation, which is characterized by the investment of vascular smooth muscle cells (vSMCs) around developing blood vessels, begins when vessels remodel into a hierarchy of proximal arteries and proximal veins that branch into...
Detecting coevolution of positively selected in turtles sperm-egg fusion proteins [0.03%]
龟类精子-卵子融合蛋白正向选择位点的协同进化检测分析
Jinxiu Dong,Hui Jiang,Lei Xiong et al.
Jinxiu Dong et al.
Physically interacting sperm-egg proteins have been identified using gene-modified animals in some mammal species. Three proteins are essential for sperm-egg binding: Izumo1 on the sperm surface, and JUNO and CD9 on the egg surface. Most pr...