Ric-8A, a GEF for heterotrimeric G-proteins, controls cranial neural crest cell polarity during migration [0.03%]
Ric-8A通过调节迁移期间颅神经嵴细胞极性来控制异三聚体G蛋白的GEF
Juan Ignacio Leal,Soraya Villaseca,Andrea Beyer et al.
Juan Ignacio Leal et al.
The neural crest (NC) is a transient embryonic cell population that migrates extensively during development. Ric-8A, a guanine nucleotide exchange factor (GEF) for different Gα subunits regulates cranial NC (CNC) cell migration in Xenopus ...
A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices [0.03%]
钙粘着蛋白N-钙黏素和E-钙黏素之间的平衡调控神经外胚层细胞命运决定
Crystal D Rogers,Lisa K Sorrells,Marianne E Bronner
Crystal D Rogers
Characterizing endogenous protein expression, interaction and function, this study identifies in vivo interactions and competitive balance between N-cadherin and E-cadherin in developing avian (Gallus gallus) neural and neural crest cells. ...
Mechanisms of stress-related muscle atrophy in fish: An ex vivo approach [0.03%]
鱼类应激相关肌肉萎缩的机制研究：一种体外方法
Julia Torres-Velarde,Raúl Llera-Herrera,Teresa García-Gasca et al.
Julia Torres-Velarde et al.
María Belén Favarolo,Silvia L López
María Belén Favarolo
Bilaterian embryos are triploblastic organisms which develop three complete germ layers (ectoderm, mesoderm, and endoderm). While the ectoderm develops mainly from the animal hemisphere, there is diversity in the location from where the end...
Superoxide dismutase 1 expression is modulated by the core pluripotency transcription factors Oct4, Sox2 and Nanog in embryonic stem cells [0.03%]
胚胎干细胞中的Oct4、Sox2和Nanog核心多能性转录因子调节超氧化物歧化酶1表达
Claudia Solari,María Victoria Petrone,Camila Vazquez Echegaray et al.
Claudia Solari et al.
Redox homeostasis is vital for cellular functions and to prevent the detrimental consequences of oxidative stress. Pluripotent stem cells (PSCs) have an enhanced antioxidant system which supports the preservation of their genome. Besides, r...
Anisotropy of cell division and epithelial sheet bending via apical constriction shape the complex folding pattern of beetle horn primordia [0.03%]
细胞分裂各向异性和顶面收缩引起的上皮片弯曲塑造甲虫角原基的复杂折叠模式
Haruhiko Adachi,Keisuke Matsuda,Teruyuki Niimi et al.
Haruhiko Adachi et al.
Insects can dramatically change their outer morphology at molting. To prepare for this drastic transformation, insects generate new external organs as folded primordia under the old cuticle. At molting, these folded primordia are physically...
Sergio González-Itier,Esteban G Contreras,Juan Larraín et al.
Sergio González-Itier et al.
Insect metamorphosis has been a classic model to understand the role of hormones in growth and timing of developmental transitions. In addition to hormones, transitions in some species are regulated by genetic programs, such as the heteroch...
Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish [0.03%]
Ripply介导的斑马鱼前肠体中段基因表达抑制的机能作用
Hirofumi Kinoshita,Nanae Ohgane,Yuuri Fujino et al.
Hirofumi Kinoshita et al.
Somites sequentially form with a regular interval by the segmentation from the anterior region of the presomitic mesoderm (PSM). The expression of several genes involved in the somite segmentation is switched off at the transition from the ...
Andrea M J Weiner
Andrea M J Weiner
MicroRNAs are small noncoding RNAs that can control gene expression by base pairing to partially complementary mRNAs. Regulation by microRNAs plays essential roles in diverse biological processes such as neural crest formation during embryo...
The neuromuscular junction of Xenopus tadpoles: Revisiting a classical model of early synaptogenesis and regeneration [0.03%]
非洲爪蟾幼体的神经肌肉接头：重温早期突触发生和再生的经典模型
Francisca Bermedo-García,Jorge Ojeda,Emilio E Méndez-Olivos et al.
Francisca Bermedo-García et al.
The frog neuromuscular junction (NMJ) has been extensively used as a model system to dissect the mechanisms involved in synapse formation, maturation, maintenance, regeneration, and function. Early NMJ synaptogenesis relies on a combination...