The association of cytokines genes (IL-6 and IL-10) with the susceptibility to schizophrenia: A systematic review and meta-analysis [0.03%]
白细胞介素基因与精神分裂症易感性的关联：系统性回顾和元分析
Thelma Beatriz González-Castro,Carlos Alfonso Tovilla-Zárate,Isela Esther Juárez-Rojop et al.
Thelma Beatriz González-Castro et al.
Cytokines are among the important effectors and messenger molecules for restoring the homeostasis tissue after an inflammatory response. The association between IL-6 and IL-10 genes polymorphisms with the schizophrenia susceptibility have y...
Meta-Analysis
Brain research. 2024 Jan 1:1822:148667. DOI:10.1016/j.brainres.2023.148667 2024
Links among genetic variants and hierarchical brain structural and functional networks for antidepressant treatment: A multivariate study [0.03%]
抗抑郁治疗的遗传变异与分层脑结构和功能网络之间的联系：多变量研究
Yurong Sun,Yingling Hou,Xinyi Wang et al.
Yurong Sun et al.
Background: Antidepressant treatment effects are strongly heritable and have substantial effects on brain function and structure, but the underlying mechanisms are still poorly understood. In this research, we aimed to ev...
A rat model established by simulating genetic-environmental interactions recapitulates human Alzheimer's disease pathology [0.03%]
模拟基因-环境相互作用建立的小鼠模型重现了人类阿尔茨海默病病理特征
Xiaomei Lin,Tianyuyi Feng,Erheng Cui et al.
Xiaomei Lin et al.
Background: In humans, Alzheimer's disease (AD) is typically sporadic in nature, and its pathology is usually influenced by extensive factors. The study established a rat model based on the genetic-environmental interacti...
Metformin treatment reduces inflammation, dysmyelination and disease severity in a mouse model of multiple sclerosis, experimental autoimmune encephalomyelitis [0.03%]
二甲双胍治疗可减少小鼠炎症性脱髓鞘病模型的炎症、脱髓鞘及疾病严重程度
Emily A B Gilbert,Jessica Livingston,Emilio Garcia Flores et al.
Emily A B Gilbert et al.
Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation, death or damage of oligodendrocytes, and axonal degeneration. Current MS treatments are non-curative, associated with undesired side-effects, and expensive, hig...
Chemokine receptor CXCR4 interacts with nuclear receptor Nur77 and promote glioma invasion and progression [0.03%]
趋化因子受体CXCR4与核受体Nur77互作并促进胶质瘤侵袭和进展
Yuxiang Dai,Chen Yu,Lu Zhou et al.
Yuxiang Dai et al.
Background: Glioma is the most common primary brain tumor. It is prone to progress and have high rate of mortality regardless of radiation or chemotherapy due to its invasive growth features. Chemokine and its receptor CX...
Electroacupuncture pretreatment alleviates spasticity after stroke in rats by inducing the NF-κB/NLRP3 signaling pathway and the gut-brain axis [0.03%]
电针预处理通过诱导NF-κB/NLRP3信号通路和肠-脑轴减轻卒中后大鼠痉挛
Xiuqi Sun,Anbang Zhang,Bo Pang et al.
Xiuqi Sun et al.
Objective: Spasticity is one of the most prevalent ischemic stroke sequelae and the leading cause of disability after stroke. Although electroacupuncture pretreatment has been shown to be effective in the treatment of isc...
Electroacupuncture stimulation to modulate neural oscillations in promoting neurological rehabilitation [0.03%]
电针刺激调节神经振荡促进神经康复的作用研究
Ruiren Wu,Hongli Ma,Jun Hu et al.
Ruiren Wu et al.
Electroacupuncture (EA) stimulation is a modern neuromodulation technique that integrates traditional Chinese acupuncture therapy with contemporary electrical stimulation. It involves the application of electrical currents to specific acupo...
Artificial sharp-wave-ripples to support memory and counter neurodegeneration [0.03%]
人工生成尖波涟漪以增强记忆和对抗神经退行性变
Julian Keil,Hanni Kiiski,Liam Doherty et al.
Julian Keil et al.
Information processed in our sensory neocortical areas is transported to the hippocampus during memory encoding, and between hippocampus and neocortex during memory consolidation, and retrieval. Short bursts of high-frequency oscillations, ...
Ghazaleh Ghaffaripour Jahromi,Sepideh Razi,Nima Rezaei
Ghazaleh Ghaffaripour Jahromi
Depression holds the title of the largest contributor to worldwide disability, with the numbers expected to continue growing. Currently, there are neither reliable biomarkers for the diagnosis of the disease nor are the current medications ...
The effects of eight weeks of aerobic training with vitamin C on the expression pathway of antioxidants in the hippocampus tissue of TMT induced Alzheimer's disease rats [0.03%]
8周有氧锻炼结合维生素C对TMT诱导的阿尔兹海默病大鼠海马组织抗氧化途径表达的影响
Seyed Ahmad Hashemi,Zahra Ghadimi,Hadi Ghaedi et al.
Seyed Ahmad Hashemi et al.
Introduction: Alzheimer's disease (AD) is one of the most common neurological disorders and, researchers believe that the impairment of oxidant-antioxidant system plays an important role in its progression. The PI3K/NRF2 ...