Hepatitis A, B, C and E virus markers in Chinese residing in Tokyo, Japan [0.03%]
居住在日本东京的中国人戊肝、甲肝、乙肝和丙肝病毒感染标志物调查研究
Jun Yan,Tatsuo Kanda,Shuang Wu et al.
Jun Yan et al.
Aim: Recently, the number of foreigners living in Japan has been increasing, with the majority originating from China. It is important for us to know the prevalence of hepatitis virus markers among them, as proper medica...
In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma [0.03%]
二甲双胍体外和体内的抗肿瘤作用研究肝细胞癌
Zhan Qu,Yangde Zhang,Mingmei Liao et al.
Zhan Qu et al.
Aims: Metformin is a biguanide that has been widely used to treat type 2 diabetes. Several studies have shown that metformin is also effective in treating cancer, including hepatocellular carcinoma (HCC). The objective o...
Prediction of recurrence of hepatocellular carcinoma after curative hepatectomy using preoperative Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein [0.03%]
术前使用 Lens 眼蛋白凝集反应性甲胎蛋白分型预测肝癌切除术后复发
Yu Saito,Mitsuo Shimada,Tohru Utsunomiya et al.
Yu Saito et al.
Aim: Lens culinaris agglutinin A-reactive fraction of α-fetoprotein (AFP-L3) status has been reported to be an independent prognostic factor in patients with hepatocellular carcinoma (HCC). In this study, we evaluated t...
Non-inflammatory centrilobular sinusoidal fibrosis in pediatric liver transplant recipients under tacrolimus withdrawal [0.03%]
他克莫司减量的儿童肝移植受者肝脏非炎性中央静脉周围窦隙纤维化病理特征
Hiroto Egawa,Aya Miyagawa-Hayashino,Hironori Haga et al.
Hiroto Egawa et al.
Aim: We hypothesized that non-inflammatory central sinusoidal fibrosis (NICSF) is a sign of inadequate immunosuppression in children after living-donor liver transplantation. ...
Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication [0.03%]
白细胞介素-28B基因型对丙型肝炎病毒体外和体内复制系统的影响
Kazuaki Chayama,C Nelson Hayes,Michio Imamura
Kazuaki Chayama
Identification of the relationship between the interleukin (IL)-28B genotype and the effect of peginterferon plus ribavirin treatment has had a great impact on the study of antiviral therapy for patients with chronic hepatitis C virus (HCV)...
Hepatitis B virus directly promotes collagen I expression of LX-2 cells without infection in vitro [0.03%]
乙型肝炎病毒通过非感染机制促进LX-2细胞胶原蛋白I表达
Xiaoning Wu,Yu Wang,Yan Cui et al.
Xiaoning Wu et al.
Aim: To investigate direct effects of hepatitis B virus (HBV) on collagen type I in vitro. Methods: Collagen type I were measured aft...
Accuracy and reliability of microbubble ultrasound measurements for the non-invasive assessment of hepatic fibrosis in chronic hepatitis C [0.03%]
微泡超声测量无创评价慢性丙型肝炎患者肝纤维化的准确性和可靠性
Jeremy F L Cobbold,Dhupal Patel,Julie A Fitzpatrick et al.
Jeremy F L Cobbold et al.
Aim: Contrast-enhanced ultrasound can be used to assess liver disease severity non-invasively by observing intra- and extrahepatic hemodynamic changes. Transit times are calculated to include intra- and extrahepatic comp...
Enhanced expressions of apelin on proliferative hepatic arterial capillaries in human cirrhotic liver [0.03%]
人肝硬化肝脏中增生性肝动脉内皮细胞的血管生成素表达增强
Hiroaki Yokomori,Masaya Oda,Kazunori Yoshimura et al.
Hiroaki Yokomori et al.
Aim: Apelin (APLN), the endogenous ligand of angiotensin-like receptor 1 (APJ), is a peptide necessary for embryonic and tumor angiogenesis. Little is known about the localization and changes of APLN expression including...
Runzhi Zhu,Yajing Wang,Liangqing Zhang et al.
Runzhi Zhu et al.
In humans, oxidative stress and antioxidant defenses are the sum of a complicated network of enzymatic and non-enzymatic processes. Depending on the stage and severity of diseases, a patient's antioxidant armamentarium may increase as an ap...
Response-guided peginterferon-alpha-2b plus ribavirin therapy for chronic hepatitis C patients with genotype 2 and high viral loads [0.03%]
基于疗效应答指导的PEG干扰素α-2b联合利巴韦林治疗基因2型高病毒载量慢性丙型肝炎患者的效果分析
Ken Sato,Hiroaki Hashizume,Yuichi Yamazaki et al.
Ken Sato et al.
Aims: Optimization of the duration of peginterferon-α/ribavirin therapy in patients with hepatitis C virus (HCV) genotype 2 and high viral loads remains to be established. We sought to prospectively optimize the treatme...