Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study [0.03%]
Rosuvastatin治疗伴脂代谢紊乱的非酒精性脂肪肝病疗效的开放性试点研究
Takashi Nakahara,Hideyuki Hyogo,Yuki Kimura et al.
Takashi Nakahara et al.
Aim: Statins, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, are reported to be useful for the treatment of non-alcoholic steatohepatitis (NASH). Currently, there is no proven therapy for NASH...
Prognostic factors in patients with idiopathic portal hypertension: Two Japanese nationwide epidemiological surveys in 1999 and 2005 [0.03%]
日本两大规模流行病学调查(1999年和2005年)寻得的特发性门脉高压症患者的预后因素分析
Yoko Murai,Satoko Ohfuji,Wakaba Fukushima et al.
Yoko Murai et al.
Aim: To investigate factors affecting disease prognosis among patients with idiopathic portal hypertension (IPH). Methods: Two Japane...
Effect of specific activation of γ-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy [0.03%]
体内特异激活γ-氨基丁酸受体对扩大肝切除术后氧化应激损伤的影响
Lindsay B Gardner,Tomohide Hori,Feng Chen et al.
Lindsay B Gardner et al.
Aim: γ-Aminobutyric acid (GABA) is a multifunctional molecule with various physiological effects throughout the body. The regulation of GABA receptor (GABAR) plays a key role in reducing the damage mediated by oxidative...
Aldehyde dehydrogenase 1 is associated with recurrence-free survival but not stem cell-like properties in hepatocellular carcinoma [0.03%]
醛脱氢酶1与肝细胞癌的无复发生存率相关但不具有干细胞样特性
Eiichiro Suzuki,Tetsuhiro Chiba,Yoh Zen et al.
Eiichiro Suzuki et al.
Aim: It has been reported that aldehyde dehydrogenase 1 A1 (ALDH1) could be not only a normal stem cell marker but also a cancer stem cell marker. ALDH1 expression could be a predictor of poor prognosis in a wide range o...
Complications of radiofrequency ablation for hepatocellular carcinoma in a multicenter study: An analysis of 16 346 treated nodules in 13 283 patients [0.03%]
多中心肝癌射频消融并发症研究：基于13283例患者16346个瘤结的分析
Masahiko Koda,Yoshikazu Murawaki,Yasuaki Hirooka et al.
Masahiko Koda et al.
Aim: We surveyed multiple centers to identify types and frequency of complications and mortality rate associated with radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC). ...
Hiroo Fukada,Shunhei Yamashina,Kousuke Izumi et al.
Hiroo Fukada et al.
Aim: Recent evidence suggests that protein degradation system autophagy is implicated in a component of innate immunity. We report here that suppression of autophagy in Kupffer cells due to hepatic steatosis enhances an ...
Deanna J W Campbell,Catherine I Dumur,Nadia F Lamour et al.
Deanna J W Campbell et al.
Aim: Recent studies have suggested that increased α-smooth muscle-actin positive myofibroblastic cells (α-SMA positive CAF) in the desmoplastic stroma may relate to a more aggressive cancer and worse survival outcomes ...
Three cases of acute or fulminant hepatitis E caused by ingestion of pork meat and entrails in Hokkaido, Japan: Zoonotic food-borne transmission of hepatitis E virus and public health concerns [0.03%]
日本北海道三例因摄取猪肉及内脏感染急性或亚急性肝炎E病毒之病例：动物传染病经食品传染给人类的疑虑及其公共卫生问题
Kencho Miyashita,Jong-Hon Kang,Akiyoshi Saga et al.
Kencho Miyashita et al.
Aim: In developed countries including Japan, the transmission route of indigenous hepatitis E virus (HEV) infection is obscure. Accordingly, public health implications of indigenous HEV infection have not been well addre...
Is primary biliary cirrhosis a steroid-sensitive autoimmune disease? [0.03%]
原发性胆汁性肝硬化是一种类固醇敏感的自身免疫性疾病吗？
Ashwin Dhanda,Richard Lee,Peter Collins
Ashwin Dhanda
Case of telangiectatic/inflammatory hepatocellular adenoma arising in a patient with primary sclerosing cholangitis [0.03%]
一名原发性硬化性胆管炎患者发生毛细血管扩张/炎症型肝细胞腺瘤的病例报告
Hsu Maylee,Kenichi Harada,Saya Igarashi et al.
Hsu Maylee et al.
Hepatocellular adenomas (HCA) have been recently identified as a heterogeneous group, differing based on genotypic as well as morphological characteristics. HCA are most frequently found in women on oral contraception. A type of HCA, inflam...