High expression of angiotensin-converting enzyme and angiotensin-converting enzyme 2 in preservation injury after liver transplantation in rats [0.03%]
大鼠肝移植保存损伤中血管紧张素转化酶和血管紧张素转换酶2的高表达
Chun-Yan Xia,Ling Li,Hui-Min Liu et al.
Chun-Yan Xia et al.
Aim: To explore the possible role of local renin-angiotensin system (RAS) in preservation injury (PI) after liver transplantation by studying expression of angiotensin-converting enzyme (ACE) and angiotensin-converting en...
Zoonotic risk of hepatitis E virus (HEV): A study of HEV infection in animals and humans in suburbs of Beijing [0.03%]
北京郊区动物与人群戊型肝炎病毒(HEV)感染调查及人畜共患风险评估研究
Yibin Chang,Ling Wang,Jiabao Geng et al.
Yibin Chang et al.
Aim: To investigate hepatitis E virus (HEV) infection among different animals and workers in pig farms and slaughterhouses, and analyze the genotype of HEV isolated in this study. ...
Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4 [0.03%]
活化C激酶受体1调控ABCB4的细胞内定位和功能
Yuki Ikebuchi,Tappei Takada,Kousei Ito et al.
Yuki Ikebuchi et al.
Aim: Multidrug resistance protein 3 (MDR3/ABCB4), located on the bile canalicular membrane of hepatocytes, is responsible for the translocation of phosphatidylcholine across the plasma membrane, and its hereditary defect ...
Flow cytometric isolation and phenotypic characterization of two subsets of ED2(+) (CD163) hepatic macrophages in rats [0.03%]
大鼠肝巨噬细胞中两种ED2+(CD163+)亚群的流式细胞仪分离及表型特征分析
Yao He,Tomohito Sadahiro,Sang-Ik Noh et al.
Yao He et al.
Aims: Macrophages in the liver are well known for their functional heterogeneity. However, subpopulations of the hepatic macrophages are not well defined. ...
Vitamin K2 downregulates the expression of fibroblast growth factor receptor 3 in human hepatocellular carcinoma cells [0.03%]
维生素K2通过下调成纤维细胞生长因子受体3的表达抑制人肝癌细胞的增殖
Ke Cao,Weidong Liu,Hideji Nakamura et al.
Ke Cao et al.
Aim: Vitamin K2 exerts an antitumor activity on human hepatocellular carcinoma (HCC), however, its inhibitory mechanism has not yet been clarified. This study was designed to identify the attractive target molecule of vit...
An insight into the protection of rat liver against ischemia/reperfusion injury by 2-selenium-bridged beta-cyclodextrin [0.03%]
2-硒桥β环糊精对缺血再灌注所致大鼠肝损伤的保护作用研究
Ting-Ting Lin,Bing-Mei Wang,Xin-Yang Li et al.
Ting-Ting Lin et al.
Aim: The reperfusion following liver ischemia results in the damage and apoptosis of hepatocytes. The aim of this study was to investigate the possible effects and mechanism of a new synthesized glutathione peroxidase (GP...
Value of the extracellular water ratio for assessment of cirrhotic patients with and without ascites [0.03%]
评估伴或不伴有腹水的肝硬化患者细胞外水分比率的价值
Nagisa Hara,Motoh Iwasa,Kazuko Iwata et al.
Nagisa Hara et al.
Aims: Ascites, which often complicates liver cirrhosis, is reported to be a factor that worsens the outcome. The aims of this study were to quantify body water compartment changes in cirrhotic patients, with and without a...
Rapid loss of hepatitis C virus genotype 1b from serum in patients receiving a triple treatment with telaprevir (MP-424), pegylated interferon and ribavirin for 12 weeks [0.03%]
接受泰拉匹瑞韦、聚乙二醇干扰素和利巴韦林三联疗法12周的丙型肝炎患者血清中基因1b型迅速消失
Fumitaka Suzuki,Norio Akuta,Yoshiyuki Suzuki et al.
Fumitaka Suzuki et al.
Aim: To evaluate the efficacy and safety of the triple treatment with telaprevir (MP-424), pegylated interferon (PEG-IFN) and ribavirin during 12 weeks on-treatment. ...
Efficacy and limitation of bone marrow transplantation in the treatment of acute and subacute liver failure in rats [0.03%]
骨髓移植对急性与亚急性肝功能衰竭大鼠的疗效及局限性研究
Hirotaka Tokai,Yujo Kawashita,Yuichiro Ito et al.
Hirotaka Tokai et al.
Aim: Recent reports have shown that bone marrow cells (BMC) retain the potential to differentiate into hepatocytes. Thus, the BMC have been recognized as an attractive source for liver regenerative medicine. However, it h...
Matrine improves 17alpha-ethinyl estradiol-induced acute cholestasis in rats [0.03%]
小檗胺改善雌二醇致急性胆汁淤积的作用研究
Ying Zhao,Desheng Zhai,Hui He et al.
Ying Zhao et al.
Aim: To explore the effects of matrine (MT) on acute intrahepatic cholestasis induced by 17alpha-ethinyl estradiol (EE) in rats. Methods: ...