Histological findings in the livers of patients with neonatal intrahepatic cholestasis caused by citrin deficiency [0.03%]
由丙二酸尿症所致新生儿肝内胆汁淤积患者肝脏组织学特点分析
Akihiko Kimura,Masayoshi Kage,Ikuo Nagata et al.
Akihiko Kimura et al.
Aim: To characterize the histological features of the livers of patients with neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD), we studied specimens from 30 patients diagnosed with NICCD by geneticall...
Docetaxel inhibits progression of human hepatoma cell line in vitro and is effective in advanced hepatocellular carcinoma [0.03%]
多西紫杉醇抑制人肝癌细胞株的生长并能有效治疗晚期肝细胞癌
Yutaka Yata,Feng Xue,Terumi Takahara et al.
Yutaka Yata et al.
Background: Current chemotherapy for advanced hepatocellular carcinoma (HCC) is insufficient; only sorafenib has been proven to provide a modest survival benefit. A future direction of chemotherapy is to tailor treatment ...
Serum HGF and TGF-beta1 levels after right portal vein embolization [0.03%]
右门静脉栓塞后的血清HGF和TGF-β1水平变化
Hiromitsu Hayashi,Toru Beppu,Hiroki Sugita et al.
Hiromitsu Hayashi et al.
Aim: The changes in the serum hepatocyte growth factor (HGF) and transforming growth factor (TGF)-beta1 levels after portal vein embolization (PVE), and their clinical significance, remain unclear and we aimed to assess t...
Advantage of IFN-beta/alpha2b same-day administration for ribavirin-intolerant patients with chronic hepatitis C [0.03%]
IFN-β/α2b一天内给药治疗对利巴韦林不耐受的慢性丙型肝炎患者的疗效优势
Eiichi Tomita,Kazuki Ando,Jun-Ichi Sugihara et al.
Eiichi Tomita et al.
Aim: Although interferon (IFN)/ribavirin is the mainstream combination treatment for chronic hepatitis C in patients with a high viral load, ribavirin is problematic for women of childbearing age and patients with anemia....
Over-expression of Toll-like receptors and their ligands in small-for-size graft [0.03%]
小型移植物中 toll 样受体及其配体的过度表达
Weiwei Jiang,Mingzheng Hu,Jianhua Rao et al.
Weiwei Jiang et al.
Aim: Toll-like receptors (TLRs) participate in several physiological and pathological processes of transplantation, including inflammation and allograft rejection, but the expression of TLRs and their ligands remains unde...
Accelerated expression of a Myc target gene Mina53 in aggressive hepatocellular carcinoma [0.03%]
恶性肝细胞癌中Myc靶基因Mina53的加速表达
Sachiko Ogasawara,Mina Komuta,Osamu Nakashima et al.
Sachiko Ogasawara et al.
Aim: Expressions of the myc target genes Mina53 and mimitin are high in esophageal squamous cell carcinoma and colon cancer, and their relationship to cell proliferation and patient prognosis has been reported. Because c-...
Phase I/II study of a fine-powder formulation of cisplatin for transcatheter arterial chemoembolization in hepatocellular carcinoma [0.03%]
肝癌患者超液化顺铂载药微球经导管动脉化疗栓塞治疗Ⅰ/Ⅱ期临床研究
Masamichi Moriguchi,Tadatoshi Takayama,Masahiko Nakamura et al.
Masamichi Moriguchi et al.
Aim: The clinical feasibility of transcatheter arterial chemoembolization (TACE) with fine-powder cisplatin (CDDP) in patients with hepatocellular carcinoma (HCC) has not been investigated. A phase I/II study was conducte...
A predictive model of response to peginterferon ribavirin in chronic hepatitis C using classification and regression tree analysis [0.03%]
基于分类和回归树分析的慢性丙型肝炎患者对长效干扰素α-2a联合利巴韦林治疗应答预测模型研究
Masayuki Kurosaki,Kotaro Matsunaga,Itsuko Hirayama et al.
Masayuki Kurosaki et al.
Aim: Early disappearance of serum hepatitis C virus (HCV) RNA is the prerequisite for achieving sustained virological response (SVR) in peg-interferon (PEG-IFN) plus ribavirin (RBV) therapy for chronic hepatitis C. This s...
Antiretroviral therapy hepatotoxicity: Prevalence, risk factors, and clinical characteristics in a cohort of Han Chinese [0.03%]
抗逆转录病毒疗法肝毒性的流行病学、危险因素及临床特征——一项关于汉族人群的研究
Shicheng Gao,Xi-En Gui,Lipin Deng et al.
Shicheng Gao et al.
Aim: To investigate the incidence and risk factors of hepatotoxicity in Han Chinese patients with acquired immunodeficiency syndrome on combined anti-retroviral therapy (cART). ...
Living-donor liver transplantation from second generation children for atomic bomb survivors [0.03%]
atomic bomb受害者子女供肝的活体肝移植
Susumu Eguchi,Mitsuhisa Takatsuki,Masahiro Nakashima et al.
Susumu Eguchi et al.
No report has been available regarding organ transplantation for atomic bomb survivors, even with renal graft. We experienced a living-donor liver transplantation for two atomic bomb survivors using grafts from second-generation children. P...