Fuat Kurbanov,Yasuhito Tanaka,Masashi Mizokami
Fuat Kurbanov
Hepatitis B virus (HBV) is one of the most widely distributed viruses that infect humankind. Distinct clinical and virological characteristics of the HBV-infection have been reported in different geographical parts of the world and are incr...
Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan [0.03%]
2008年日本财政年度慢性丙型肝炎及肝硬化治疗指南
Hiromitsu Kumada,Takeshi Okanoue,Morikazu Onji et al.
Hiromitsu Kumada et al.
In the 2008 guidelines for the treatment of patients with chronic hepatitis C, pegylated interferon (Peg-IFN) combined with ribavirin for 48 weeks are indicated for treatment-naive patients infected with hepatitis C virus (HCV) of genotype ...
Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan [0.03%]
2008年日本成人慢性乙型肝炎及乙型肝炎肝硬化治疗指南
Hiromitsu Kumada,Takeshi Okanoue,Morikazu Onji et al.
Hiromitsu Kumada et al.
In the 2008 guidelines for the treatment of patients with cirrhosis, who are infected with hepatitis B virus (HBV), the main goal is to normalize levels of alanine and aspartate aminotransferases by eliminating HBV or reducing viral loads. ...
Rapid detection of clonal expansion of T-cell receptor-beta gene in patients with HBV using the real-time PCR with DNA melting curve analysis [0.03%]
HBV患者T细胞受体-β克隆性扩增的实时荧光定量PCR检测方法
Jie-Zuan Yang,Ming-Wei Li,Jian-Guo Wang et al.
Jie-Zuan Yang et al.
Aim: The gene melting spectral pattern (GMSP) of PCR products from 24 T-cell receptor beta chain variable (TCRBV) gene families was developed to determine sequence bias and feature of TCRBV CDR3 gene family. ...
Expansion of CD4(+)CD25(+)FoxP3(+) regulatory T cells in hepatitis C virus-related chronic hepatitis, cirrhosis and hepatocellular carcinoma [0.03%]
在慢性肝炎、肝硬化和肝细胞癌中与HCV有关的调节T细胞增多
Kai Yoshizawa,Hiroshi Abe,Yasuhito Kubo et al.
Kai Yoshizawa et al.
Aim: Regulatory T (Treg) cells may play a pivotal role in the persistence of hepatitis C virus (HCV) infection and the development of hepatocellular carcinoma (HCC). Therefore, we examined their frequency in peripheral bl...
Megestrol and embryonic extracts in the treatment of advanced hepatocellular carcinoma: A prospective randomized trial in the pre-sorafenib era [0.03%]
孕马雌酮和胚胎提取物在索拉非尼问世前晚期肝细胞癌治疗中的作用：一项前瞻性随机试验
Anna Giacomin,Adriana Sergio,Veronica Vanin et al.
Anna Giacomin et al.
Background: Patients with advanced hepatocellular carcinoma (HCC) achieved significant results by the new treatment with sorafenib (a multi-tyrosine kinase inhibitor), but, because it has been tested mainly in Child A cir...
Proanthocyanidin derived from the leaves of Vaccinium virgatum suppresses platelet-derived growth factor-induced proliferation of the human hepatic stellate cell line LI90 [0.03%]
源自越橘叶的原花青素可抑制血小板源性生长因子诱导的人肝星状细胞系LI90增殖
Yoichiro Takami,Hirofumi Uto,Masahiko Takeshita et al.
Yoichiro Takami et al.
Aim: Hepatic stellate cell (HSC) proliferation plays a pivotal role in liver fibrogenesis, and agents that suppress HSC activation, including platelet-derived growth factor (PDGF)-induced HSC proliferation, are good candi...
Spur cells and spur cell anemia in hospitalized patients with advanced liver disease: Incidence and correlation with disease severity and survival [0.03%]
住院的晚期肝病患者的刺细胞和刺细胞性贫血的发病率及其与疾病严重程度和生存率的相关性
Themistoklis Vassiliadis,Alexander Mpoumponaris,Sofia Vakalopoulou et al.
Themistoklis Vassiliadis et al.
Aim: Spur cell anemia (SCA) is a form of acquired hemolytic anemia seen in patients with advanced cirrhosis and particularly in patients with alcoholic cirrhosis. The aim of the present study was to evaluate the incidence...
Postoperative surveillance with monthly serum tumor markers after living-donor liver transplantation for hepatocellular carcinoma [0.03%]
肝细胞癌活体肝移植术后的血清肿瘤标志物月检制度及其效果评价
Noriyo Yamashiki,Yasuhiko Sugawara,Sumihito Tamura et al.
Noriyo Yamashiki et al.
Aim: Recurrence of hepatocellular carcinoma (HCC) after liver transplantation decreases patient survival. The usefulness of post-transplant surveillance with tumor markers, however, is not clear. We evaluated our cumulati...
Comparison between quantitative hepatitis B surface antigen, hepatitis B e-antigen and hepatitis B virus DNA levels for predicting virological response to pegylated interferon-alpha-2b therapy in hepatitis B e-antigen-positive chronic hepatitis B [0.03%]
量化HBsAg、HBeAg及HBV DNA水平预测阳性慢性乙肝患者PEG干扰素α-2b治疗病毒学应答的比较研究
Pisit Tangkijvanich,Piyawat Komolmit,Varocha Mahachai et al.
Pisit Tangkijvanich et al.
Aim: The aim of this study was to compare the clinical applicability of quantitative serum hepatitis B surface antigen (HBsAg), hepatitis B e-antigen (HBeAg) and hepatitis B virus (HBV) DNA for predicting virological resp...