Hepatocyte growth factor mobilizes and recruits hematopoietic progenitor cells into liver through a stem cell factor-mediated mechanism [0.03%]
肝细胞生长因子通过介导干细胞因子机制动员和募集造血祖细胞到肝脏
Fumihito Tajima,Hiroyuki Tsuchiya,Kenichi Nishikawa et al.
Fumihito Tajima et al.
Aims: Although bone marrow cells are reported to migrate to the liver under circumstances of severe liver injury, the bone marrow cell type and the mechanisms in this process, remain to be clarified. We examined the invol...
Ivette M Sosa Seda,Justin L Mott,Yuko Akazawa et al.
Ivette M Sosa Seda et al.
Aim: Induction of hepatic stellate cell (HSC) apoptosis is a viable therapeutic strategy to reduce liver fibrogenesis. Although BH3-only proteins of the Bcl-2 family trigger pro-apoptotic pathways, the BH3-only proteins m...
Two week induction of interferon-beta followed by pegylated interferon alpha-2b and ribavirin for chronic infection with hepatitis C [0.03%]
长效干扰素α-2b与利巴韦林联合治疗慢性丙型肝炎病毒感染的效果研究
Keiji Matsui,Shogo Iwabuchi,Hirohito Shimizu et al.
Keiji Matsui et al.
Objectives: To elucidate the efficacy of interferon (IFN)-beta induction therapy followed by pegylated IFN alpha and ribavirin for chronic infection with hepatitis C virus (HCV). ...
Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid-enhanced echogenicity in a liver of a nonalchoholic steatohepatitis rat model [0.03%]
枯否细胞吞噬功能障碍在非酒精性脂肪肝炎大鼠索诺维增强显像降低中的作用
Shohei Yoshikawa,Hiroko Iijima,Masaki Saito et al.
Shohei Yoshikawa et al.
Aims: To evaluate the dynamics of Kupffer cell (KC) phagocytosis by performing both in vivo and in vitro studies using Sonazoid (GE Healthcare, Oslo) in a rat nonalcoholic steatohepatitis (NASH) model. ...
Reply from the authors [0.03%]
作者回函
Andreas Weber,Stephanie Krebs,Cosima Lenhardt et al.
Andreas Weber et al.
Changes in liver function parameters after percutaneous radiofrequency ablation therapy in patients with hepatocellular carcinoma [0.03%]
射频消融治疗肝细胞癌患者后的肝功能变化分析
Hidekatsu Kuroda,Kazuhiro Kasai,Keisuke Kakisaka et al.
Hidekatsu Kuroda et al.
Aim: To evaluate changes in liver function parameters and risk factors 1 year after percutaneous radiofrequency ablation (RFA) therapy in patients with hepatocellular carcinoma (HCC). ...
lambda-Interferons and the single nucleotide polymorphisms: A milestone to tailor-made therapy for chronic hepatitis C [0.03%]
干扰素λ和单核苷酸多态性：慢性丙型肝炎个体化治疗的里程碑
Yasuhito Tanaka,Nao Nishida,Masaya Sugiyama et al.
Yasuhito Tanaka et al.
Type III interferons (IFN) (IFN-lambda1, -lambda2, -lambda3/interleukin [IL]-29, -28A, -28B) are cytokines with type I IFN-like antiviral activities. Most cells have expressed both type I and III IFN following Toll-like receptor (TLR) stimu...
Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic Kupffer cells [0.03%]
低氧枯否细胞通过缺氧诱导因子依赖性产生促纤维化介质
Bryan L Copple,Shan Bai,Jeon-Ok Moon
Bryan L Copple
Aim: Liver fibrosis develops when chronic liver injury stimulates cells in the liver to produce mediators that activate hepatic stellate cells and stimulate them to secrete collagen. Recent studies suggest that the hypoxi...
Selective aldosterone blocker, eplerenone, attenuates hepatocellular carcinoma growth and angiogenesis in mice [0.03%]
选择性醛固酮拮抗剂埃普利伦酮抑制小鼠肝癌生长和血管生成
Kosuke Kaji,Hitoshi Yoshiji,Mitsuteru Kitade et al.
Kosuke Kaji et al.
Aim: The renin-angiotensin-aldosterone system (RAAS) has become known as a prerequisite for tumor angiogenesis, including hepatocellular carcinoma (HCC). Although angiotensin II is known to play an important role in tumor...
Effect of long-term late-evening snack on health-related quality of life in cirrhotic patients [0.03%]
长期睡前小吃对肝硬化患者生命质量的影响
Hisami Yamanaka-Okumura,Taki Nakamura,Hidenori Miyake et al.
Hisami Yamanaka-Okumura et al.
Aim: In patients with liver cirrhosis, abnormal energy metabolism induces low health-related quality of life (HRQOL) scores. However, late-evening snack (LES) prevents morning starvation in cirrhotic patients. Our aim is ...