Hepatitis A outbreak associated with a revolving sushi bar in Chiba, Japan: Application of molecular epidemiology [0.03%]
日本千叶县一家旋转寿司店关联的甲型肝炎暴发：分子流行病学的应用
Atsuko Tominaga,Tatsuo Kanda,Taro Akiike et al.
Atsuko Tominaga et al.
Aim: The number of hepatitis A cases in Japan as well as in other developed countries has been progressively decreasing during the last several years. There is no universal hepatitis A vaccination program in Japan, and a...
Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 2 and high virus load [0.03%]
老年丙型肝炎2型高病毒量患者的减量干扰素α与利巴韦林治疗效果分析
Yasuji Arase,Yoshiyuki Suzuki,Fumitaka Suzuki et al.
Yasuji Arase et al.
Aim: To evaluate the efficacy of natural human interferon (IFN)-β and ribavirin in elderly patients infected with hepatitis C virus (HCV) genotype 2 and high virus load. ...
Huge focal nodular hyperplasia difficult to distinguish from well-differentiated hepatocellular carcinoma [0.03%]
巨大的肝硬化结节性再生病灶与分化良好的肝细胞癌鉴别困难
Jun Hanaoka,Mitsuo Shimada,Tohru Utsunomiya et al.
Jun Hanaoka et al.
We present a 43-year-old man with huge focal nodular hyperplasia (FNH) that was difficult to distinguish from well-differentiated hepatocellular carcinoma (HCC). He previously had abnormal portal vein circulation due to hypoplasia of the in...
Projected focal nodular hyperplasia of the liver with pronounced atypical ductular reaction resembling ductal plate and expressing KIT [0.03%]
类似胆管板并表达KITT FH的预期焦点性肝结节增生伴有明显的非典型胆管反应
Tadashi Terada
Tadashi Terada
A 26-year-old woman was found to have a left abdominal tumor in the space among the hepatic left lobe, stomach and spleen. A laparoscopic examination revealed that the tumor was a projected liver tumor, and resection of the tumor was perfor...
Lipid profiling of pre-treatment liver biopsy tissue predicts sustained virological response in patients with chronic hepatitis C [0.03%]
治疗前肝组织活检脂质组学检测可预测慢性丙型肝炎患者的持续病毒学应答反应
Jeremy F L Cobbold,I Jane Cox,Ashley S Brown et al.
Jeremy F L Cobbold et al.
Aim: Hepatic lipid is important in the pathogenesis and progression of hepatitis C-related liver disease. Polyunsaturated fatty acids have been shown to reduce viral replication in cell culture. Proton magic angle spinni...
Prevention of hepatitis B virus reactivation in patients receiving immunosuppressive therapy or chemotherapy [0.03%]
免疫抑制治疗或化疗患者的乙型肝炎病毒再激活的预防措施
Makoto Oketani,Akio Ido,Hirofumi Uto et al.
Makoto Oketani et al.
With the increasing use of potent immunosuppressive therapy, reactivation of hepatitis B virus (HBV) in endemic regions is becoming a clinical problem requiring special attention. A recent annual nationwide survey clarified that HBV reactiv...
Guidelines on nutritional management in Japanese patients with liver cirrhosis from the perspective of preventing hepatocellular carcinoma [0.03%]
从预防肝细胞癌角度出发的日本肝硬化患者营养管理指南
Kazuyuki Suzuki,Ryujin Endo,Yutaka Kohgo et al.
Kazuyuki Suzuki et al.
Aim: The Japanese Nutritional Study Group for Liver Cirrhosis (JNUS) was assembled in 2008 with the support of a Health Labor Sciences Research Grant from the Ministry of Health, Labor and Welfare of Japan. The goal of t...
Changes in sequences of core region, interferon sensitivity-determining region and interferon and ribavirin resistance-determining region of hepatitis C virus genotype 1 during interferon-alpha and ribavirin therapy, and efficacy of retreatment [0.03%]
丙型肝炎病毒1b基因型核心区、ISDR和IFN耐药决定区的核苷酸序列变化以及干扰素α联合利巴韦林治疗及再治疗的效果
Ritsuzo Kozuka,Masaru Enomoto,Hoang Hai et al.
Ritsuzo Kozuka et al.
Aim: Some regions associated with sensitivity to interferon-α and ribavirin have been identified in the hepatitis C virus (HCV) genome, including amino acid 70 in the core region (core a.a. 70), a.a. 2209-2248 (interfer...
Prevalence of restless legs syndrome in Japanese patients with chronic liver disease [0.03%]
日本慢性肝病患者不安腿综合征的患病率
Toshihisa Matsuzaki,Tatsuki Ichikawa,Hideaki Kondo et al.
Toshihisa Matsuzaki et al.
Aim: Sleep disturbance is a major complication in patients with chronic liver disease, but causes are unclear. The aim of this study was to clarify the prevalence of restless legs syndrome (RLS) in Japanese chronic liver...
Development of specific and quantitative real-time detection PCR and immunoassays for λ3-interferon [0.03%]
λ3干扰素的定量实时检测PCR和免疫检测试剂盒的建立及鉴定
Masaya Sugiyama,Tatsuji Kimura,Shigeko Naito et al.
Masaya Sugiyama et al.
Aim: Single nucleotide polymorphisms (SNP) around interferon (IFN)-λ3 have been associated with the response to pegylated IFN-α treatment for chronic hepatitis C. Specific quantification methods for IFN-λ3 are require...