Spontaneously hypertensive rats develop pronounced hepatic steatosis induced by choline-deficient diet: Evidence for hypertension as a potential enhancer in non-alcoholic steatohepatitis [0.03%]
自发性高血压大鼠由胆碱缺乏型饮食诱导的肝脂肪变性：高血压可能增强非酒精性脂肪肝病的证据
Takuya Ikuta,Keishi Kanno,Koji Arihiro et al.
Takuya Ikuta et al.
Aim: Patients with non-alcoholic steatohepatitis (NASH) frequently have many co-morbidities including essential hypertension, which is reported to increase vascular production of reactive oxygen species (ROS) and alter t...
Difference in malignancies of chronic liver disease due to non-alcoholic fatty liver disease or hepatitis C in Japanese elderly patients [0.03%]
日本老年患者非酒精性脂肪肝病或丙型肝炎所致慢性肝病恶性肿瘤差异分析
Yasuji Arase,Mariko Kobayashi,Fumitaka Suzuki et al.
Yasuji Arase et al.
Aim: Malignancies that include hepatocellular carcinoma often occurred in patients with chronic liver disease. The aim of this retrospective match control study was to assess the cumulative development incidence and pred...
Yasuaki Takeyama,Shotaro Sakisaka
Yasuaki Takeyama
The secretion of bile normally depends on the function of a number of membrane transport systems in hepatocytes and cholangiocytes. The transport of solutes from the blood to the bile is driven by transport systems in the plasma membrane of...
Extensive portal and mesenteric vein thrombosis in a young man with Klinefelter's syndrome [0.03%]
克氏综合征青年男子的广泛门静脉和肠系膜静脉血栓形成
Yasutaka Matsunaga,Akira Goto,Hideki Wakasugi et al.
Yasutaka Matsunaga et al.
Klinefelter's syndrome (KS) is a unique physical condition characterized by tall stature, eunuchoid body proportions, gynecomastia, and azoospermia, in addition to an extra X chromosome. In contrast to the original description, symptoms or ...
Cucurbitacin B inhibits 12-O-tetradecanoylphorbol 13-acetate-induced invasion and migration of human hepatoma cells through inactivating mitogen-activated protein kinase and PI3K/Akt signal transduction pathways [0.03%]
cucurbitacin B通过失活促分裂原活化蛋白激酶及PI3K/Akt信号转导通路抑制12-O-十四烷酰佛波酯13-acetate致人肝癌细胞的侵袭和迁移
Xueying Zhou,Jiao Yang,Yanli Wang et al.
Xueying Zhou et al.
Aim: Cucurbitacin B (CuB) is an active component isolated from various plants used as folk medicine in Asian countries and has shown diverse antitumor activities. There is, however, no documented effect of CuB on the mig...
Recent trend of clinical features in patients with hepatocellular carcinoma [0.03%]
近年来肝细胞癌临床特征的变化趋势
Yuko Nagaoki,Hideyuki Hyogo,Hiroshi Aikata et al.
Yuko Nagaoki et al.
Aim: In this study, we evaluated the clinical characteristics of hepatocellular carcinoma (HCC) because the etiology of HCC has been changing recently. M...
Kentaro Yoshioka,Senju Hashimoto
Kentaro Yoshioka
Transient elastgraphy, acoustic radiation force impulse and real-time elastography are the methods with very good or excellent diagnostic accuracy for the assessment of liver fibrosis stage. They do not provide the information on inflammato...
Possible widespread presence of hepatitis A virus subgenotype IIIA in Japan: Recent trend of hepatitis A causing acute liver failure [0.03%]
日本丙型肝炎病毒III亚基因组型可能广泛存在：近期丙型肝炎导致急性肝衰竭的新趋势
Tatsuo Miyamura,Koji Ishii,Tatsuo Kanda et al.
Tatsuo Miyamura et al.
Aim: Recently, the number of acute hepatitis A cases has decreased in Japan. However, six patients with acute liver failure caused by hepatitis A virus (HAV) have been admitted to Chiba University Hospital, Japan, in the...
Predictive factors for cholangiocarcinoma associated with hepatolithiasis determined on the basis of Japanese Multicenter study [0.03%]
基于日本多中心研究的肝内胆管结石相关胆囊癌预测因素分析
Yutaka Suzuki,Toshiyuki Mori,Nobutsugu Abe et al.
Yutaka Suzuki et al.
Aim: The aim of this study was to delineate predictive factors for cholangiocarcinoma in patients with hepatolithiasis, and to establish optimal management for hepatolithiasis from the viewpoint of carcinogenesis on the ...
Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma and future treatments for the poor responders [0.03%]
肝动脉灌注化疗用于治疗晚期肝细胞癌及难治型患者的未来疗法探究
Takahiro Yamasaki,Isao Sakaida
Takahiro Yamasaki
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The most common problem associated with HCC is a high risk of intrahepatic recurrence despite radical treatment, and in many patients, this recurrence has fatal con...