Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype [0.03%]
脾切除预防肝移植后复发性丙型肝炎患者发生溶血性贫血的效果与肌苷三磷酸焦磷酸酶基因型无关
Takashi Motomura,Erina Koga,Akinobu Taketomi et al.
Takashi Motomura et al.
Aim: A genetic polymorphism of inosine triphosphate pyrophosphatase (ITPA) has been associated with pegylated-interferon/ribavirin (PEG-IFN/RBV)-induced anemia in chronic hepatitis C patients. However, correlation of the...
Prediction and prevention of intrahepatic recurrence of hepatocellular carcinoma [0.03%]
肝细胞癌的复发预测及预防措施研究进展
Namiki Izumi
Namiki Izumi
Hepatocellular carcinoma (HCC) has characteristic features of the coexistence of two life-threatening conditions, cancer and cirrhosis, which makes prognostic assessment difficult. In addition, the high rate of intrahepatic recurrence is a ...
Weight-based high- and low-dose ribavirin in combination with peginterferon α-2b therapy for genotype 2 chronic hepatitis C: A randomized trial [0.03%]
利巴韦林个体化剂量联合聚乙二醇干扰素α-2b治疗丙型肝炎随机对照试验
Tatehiro Kagawa,Sei-Ichiro Kojima,Koichi Shiraishi et al.
Tatehiro Kagawa et al.
Aim: The optimal ribavirin dose in the treatment of patients infected with hepatitis C virus (HCV) genotype 2 remains to be elucidated. We aimed to seek the optimal ribavirin dose required for this genotype in a randomiz...
Hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic interferon-α for advanced hepatocellular carcinoma in combination with or without three-dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferior vena cava [0.03%]
肝内门静脉癌栓形成的大肠癌患者术后的生存率分析
Eisuke Murakami,Hiroshi Aikata,Daisuke Miyaki et al.
Eisuke Murakami et al.
Aim: We investigated the efficacy of hepatic arterial infusion chemotherapy (HAIC) using 5-fluorouracil (5-FU) and systemic interferon (IFN)-α (HAIC-5-FU/IFN) for advanced hepatocellular carcinoma (HCC) with venous tumo...
Comparative study of cisplatin-iodized oil suspension and emulsion for transcatheter arterial chemoembolization of rabbit VX2 liver tumors [0.03%]
兔VX2肝肿瘤介入化疗栓塞用顺铂碘化油混悬液与乳状液的比较研究
Takahiko Mine,Satoru Murata,Tatsuo Ueda et al.
Takahiko Mine et al.
Aim: To evaluate the antitumor effects and hepatotoxicity of transcatheter arterial chemoembolization (TACE) with cisplatin-iodized oil suspension and emulsion in a rabbit tumor model. ...
Impact of balloon-occluded retrograde transvenous obliteration on management of isolated fundal gastric variceal bleeding [0.03%]
球囊阻断逆行静脉栓塞法对孤立胃底静脉曲张出血治疗的影响研究
Tomohiko Akahoshi,Morimasa Tomikawa,Masao Kamori et al.
Tomohiko Akahoshi et al.
Aim: Although endoscopic injection of cyanoacrylate (CA) is the only effective method for treating isolated fundal gastric variceal bleeding, the rebleeding rate is relatively high. This study investigated the efficacy o...
High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism [0.03%]
高脂饮食诱导的肝脏脂肪变性和胰岛素抵抗：鞘脂代谢失调的作用
Lisa Longato,Ming Tong,Jack R Wands et al.
Lisa Longato et al.
Aim: Non-alcoholic fatty liver disease (NAFLD) is an insulin resistance disease that can progress to cirrhosis and liver failure. We hypothesized that in NAFLD, insulin resistance dysregulates lipid metabolism, increasin...
Occurrence of clinical depression during combination therapy with pegylated interferon alpha or natural human interferon beta plus ribavirin [0.03%]
聚乙二醇干扰素或普通干扰素与利巴韦林联合治疗时抑郁症的发作
Hideyuki Nomura,Yuugou Miyagi,Hironori Tanimoto et al.
Hideyuki Nomura et al.
Aim: The onset of depression symptoms during pegylated interferon α plus ribavirin (PEG-IFN/RBV) combination therapy has led to treatment discontinuation in some cases. In the present study, we conducted a questionnaire...
Protective hepatitis B surface antibodies in blood and ascites fluid in the early stage after liver transplantation for hepatitis B diseases [0.03%]
乙型肝炎患者肝移植术后早期外周血和腹水中保护性乙肝表面抗体的研究
Kai Wang,Zhi-Jun Zhu,Hong Zheng et al.
Kai Wang et al.
Aim: The aim of this study is to identify the titres of protective hepatitis B surface antibodies (anti-HBs) in the blood and their effective factors in the early stage after liver transplantation (LT) for hepatitis B vi...
Waka Ohishi,Kazuaki Chayama
Waka Ohishi
Recently antiviral therapies for chronic hepatitis B using nucleos(t)ide analogues have become standard treatment modalities on the basis of several independent guidelines, starting with those of the American Association for the Study of Li...