Japanese case of Budd-Chiari syndrome due to hepatic vein thrombosis successfully treated with liver transplantation [0.03%]
一例由肝静脉血栓形成的布加综合征的肝移植治疗
Tomohiro Iwasaki,Hirokazu Kawai,Koushi Oseki et al.
Tomohiro Iwasaki et al.
A 22-year-old Japanese woman was found to have severe esophageal varices and then suffered from hepatic encephalopathy. She was diagnosed with Budd-Chiari syndrome (BCS) due to hepatic vein (HV) thrombosis accompanied by portal vein thrombo...
Tissue-specific differences in inflammatory infiltrate and matrix metalloproteinase expression in adipose tissue and liver of mice with diet-induced obesity [0.03%]
高脂饮食诱导的肥胖小鼠不同组织中炎症浸润和基质金属蛋白酶表达的差异性研究
Vincent E de Meijer,Deanna Y Sverdlov,Hau D Le et al.
Vincent E de Meijer et al.
Aim: While low grade inflammation persists in both visceral fat and hepatic tissue in obesity, these changes often result in progressive disease and fibrosis only in the liver and not in adipose tissue. We hypothesized t...
Prevalence and predictive factors of diabetes in hepatitis virus positive liver cirrhosis with fasting plasma glucose level of <126 mg/dL [0.03%]
乙肝或丙肝相关肝硬化患者空腹血糖异常糖尿病筛查阳性率及预测因素分析
Naoki Matsumoto,Yasuji Arase,Yuya Seko et al.
Naoki Matsumoto et al.
Aim: The aim of this study was to evaluate the prevalence and predictive factors of diabetes in hepatitis virus positive liver cirrhotic patients with fasting plasma glucose (FPG) level of
Eiji Morita,Tamotsu Yoshimori
Eiji Morita
Autophagy is a stress response that is upregulated in response to signals such as starvation, growth factor deprivation, endoplasmic reticulum stress, and pathogen infection. Defects in this pathway are the underlying cause of a number of d...
Generation of a cholangiocyte-specific cDNA expression library for the identification of B and T cell autoantigens in murine biliary disease [0.03%]
生成胆管细胞特异性cDNA表达文库以鉴定鼠胆道疾病的B和T细胞自身抗原
Rebecca M Tucker,Cara L Mack
Rebecca M Tucker
Aim: Several mouse models of inflammatory cholangiopathies exist, including biliary atresia, primary biliary cirrhosis, autoimmune hepatitis, and primary sclerosing cholangitis. In an ongoing effort to identify the targe...
Distinctive expression of CD133 between intraductal papillary neoplasms of the bile duct and bile duct adenocarcinomas [0.03%]
胆管乳头状瘤和腺癌中CD133表达的差异性研究
Izuru Ohtsubo,Tetsuo Ajiki,Yuichi Hori et al.
Izuru Ohtsubo et al.
Aim: Intraductal papillary neoplasm of the bile duct (IPNB), a novel entity of biliary disease, is recently advocated as the counterpart of pancreatic intraductal papillary mucinous neoplasm (IPMN) because both are in co...
Hepatitis C virus core protein upregulates the expression of vascular endothelial growth factor via the nuclear factor-κB/hypoxia-inducible factor-1α axis under hypoxic conditions [0.03%]
缺氧条件下HBV X蛋白通过NF-κB/HIF-1α轴诱导VEGF表达的作用及机制研究
Mitsuhiko Abe,Hironori Koga,Takafumi Yoshida et al.
Mitsuhiko Abe et al.
Aim: Hepatitis C virus (HCV) core protein critically contributes to hepatocarcinogenesis, which is often observed in liver cirrhosis. Since the liver cirrhosis microenvironment is affected by hypoxia, we focused on the p...
Green tea polyphenol epigallocatechin-3-gallate enhances 5-fluorouracil-induced cell growth inhibition of hepatocellular carcinoma cells [0.03%]
表没食子儿茶素-3-галлат增强5-氟尿嘧啶对肝癌细胞增殖的抑制作用
Xue-Wei Yang,Xiao-Li Wang,Liang-Qi Cao et al.
Xue-Wei Yang et al.
Aim: 5-Fluorouracil (5-FU) is one of the most commonly used chemotherapeutic drugs. Resistance to 5-FU is a major cause of chemotherapy failure in advanced-stage hepatocellular carcinoma (HCC). Green tea polyphenol Epiga...
Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis [0.03%]
针对IV型胶原7SD的酶联免疫吸附测定（P4NP 7SD）：与肝纤维化期间细胞外基质重塑相关的标志物
Diana J Leeming,Mette J Nielsen,Yueqin Dai et al.
Diana J Leeming et al.
Aim: The present study describes the ability of a newly developed N-terminal pro-peptides of type IV collagen 7S domain (P4NP 7S) competitive enzyme-linked immunosorbent assay (ELISA) for describing liver fibrosis. The a...
Cost-effectiveness analysis on the surveillance for hepatocellular carcinoma in liver cirrhosis patients using contrast-enhanced ultrasonography [0.03%]
乙型肝炎和丙型肝炎肝硬化患者中对比增强超声筛查肝细胞癌的成本效益分析
Hironori Tanaka,Hiroko Iijima,Kazuhiro Nouso et al.
Hironori Tanaka et al.
Aim: Sonazoid is a new contrast agent for ultrasonography (US). Contrast-enhanced ultrasonography (CEUS) using Sonazoid enables Kupffer imaging, which improves the sensitivity of hepatocellular carcinoma (HCC) detection....