Abdul-Rahman A Al-Majed,Ebrahim Assiri,Nasr Y Khalil et al.
Abdul-Rahman A Al-Majed et al.
Losartan (Cozaar™) is an angiotensin II receptor antagonist with antihypertensive activity. It is used in the management of hypertension and heart failure. Nomenclature, formulae, elemental analysis, and appearance of the drug are included...
Glutathione [0.03%]
谷胱甘肽
Amer M Alanazi,Gamal A E Mostafa,Abdullah A Al-Badr
Amer M Alanazi
Glutathione is an endogenous peptide with antioxidant and other metabolic functions. The nomenclature, formulae, elemental composition, and appearance and uses of the drug are included. The methods used for the synthesis and biosynthesis of...
Nadia G Haress
Nadia G Haress
Cinnarizine is a piperazine derivative with antihistaminic, antiserotonergic, antidopaminergic, and calcium channel-blocking activities. A comprehensive profile was performed on cinnarizine including its description and the different method...
Preface to volume 39 [0.03%]
卷三十九序言
Harry G Brittain
Harry G Brittain
Vardenafil dihydrochloride [0.03%]
盐酸瓦他尼尔
Abdelkader E Ashour,A F M Motiur Rahman,Mohammed G Kassem
Abdelkader E Ashour
Vardenafil (VAR) is synthetic, highly selective, and potent inhibitor of phosphodiesterase-5 which competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. It is clinically approved for treatme...
Pravastatin sodium [0.03%]
普伐他汀钠
Abdullah A Al-Badr,Gamal A E Mostafa
Abdullah A Al-Badr
Pravastatin sodium is an [HMG-CoA] reductase inhibitor and is a lipid-regulating drug. This monograph includes the description of the drug: nomenclature, formulae, elemental composition, solubility, appearance, and partition coefficient. Th...
Moxifloxacin hydrochloride [0.03%]
盐酸莫西沙星
Mahmoud M H Al Omari,Deema S Jaafari,Khaldoun A Al-Souod et al.
Mahmoud M H Al Omari et al.
A comprehensive profile of moxifloxacin HCl with 198 references is reported. A full description including nomenclature, formulae, elemental analysis, and appearance is included. Methods of preparation for moxifloxacin HCl, its intermediates...
Imatinib mesylate [0.03%]
甲磺酸伊马替尼
Badraddin M H Al-Hadiya,Ahmed H H Bakheit,Ahmed A Abd-Elgalil
Badraddin M H Al-Hadiya
Imatinib (INN), marketed by Novartis as Gleevec (United States) or Glivec (Europe/Australia/Latin America), received Food & Drug Administration (FDA) approval in May 2001 and is a tyrosine kinase inhibitor used in the treatment of multiple ...
Gefitinib [0.03%]
吉非替尼药代动力学的种族差异:体外和临床研究综合分析
A F M Motiur Rahman,Hesham M Korashy,Mohammed Gabr Kassem
A F M Motiur Rahman
Gefitinib (Iressa®) is a selective inhibitor of epidermal growth factor, a growth factor that plays a pivotal role in the control of cell growth, apoptosis, and angiogenesis. Gefitinib is clinically used for the treatment of chemoresistant...
Hesham M Korashy,A F M Motiur Rahman,Mohammed Gabr Kassem
Hesham M Korashy
Dasatinib (Sprycel®), a second-generation TKI, has been shown to be effective as an anticancer drug in the treatment of patients with chronic myeloid leukemia or Philadelphia chromosome-positive acute lymphoblastic leukemia who are resista...