Yahya M Alshehri,Abdulrahman A Al-Majed,Mohamed W Attwa et al.
Yahya M Alshehri et al.
Lodenafil is a class of drugs called an inhibitor of PDE5 which also include a wide range of other erectile medicines, such as sildenafil, tadalafil and vardenafil. It is part of a new generation of PDE5 inhibitors that includes udenafil an...
Nasr Y Khalil,Ahmed H Bakheit,Hamad M Alkahtani et al.
Nasr Y Khalil et al.
Vinpocetine (VIN) is a herbal supplement extracted from the periwinkle plant. It is a multi-action agent, which is used to treat various neurological disorders such as Alzheimer's and Parkinson's disease. Vinpocetine has also anti-inflammat...
Abdulrahman A Al-Majed
Abdulrahman A Al-Majed
Majed J Al-Wadei,Ahmed H Bakheit,Alaa A-M Abdel-Aziz et al.
Majed J Al-Wadei et al.
Betaxolol is a relatively cardioselective β-adrenoceptor blocking drug, with no partial agonist (intrinsic sympathomimetic) activity and weak membrane-stabilizing (local anesthetic) activity. Betaxolol selectively and competitively binds t...
Ahmed H Bakheit,Raisuddin Ali,Ali D Alshahrani et al.
Ahmed H Bakheit et al.
The present study describes a comprehensive profile of Bisoprolol including detailed nomenclature; formulae, elemental analysis, appearance, its uses, applications, and methods for the preparation are outlined. The profile contains physicoc...
Validation of in-vitro bioassay methods: Application in herbal drug research [0.03%]
体外生物测定方法的验证在中药研究中的应用
Gunawan Indrayanto,Galih Satrio Putra,Farida Suhud
Gunawan Indrayanto
This present review described the validation method of in-vitro bioassay for its application in herbal drug research. Seven sequencing steps that can be taken for performing a valid bioassay include: literature survey, sample stability eval...
Ibrahim A Darwish,Hany W Darwish,Ahmed H Bakheit et al.
Ibrahim A Darwish et al.
Irbesartan, (2-butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one), is a member of non-peptide angiotensin II receptor antagonists used worldwide in the treatment of hypertension and diabetic ne...
Ahmed H Bakheit,Hamad M Al-Kahtani,Salem Albraiki
Ahmed H Bakheit
Rabeprazole belongs to the class of anti-secretory drugs, with benzimidazoles substitution. These drugs induce gastric acid secretion through precise inhibition of the enzyme H+/K+-ATPase (acid or proton pump). This effect helps to treat an...
Ibrahim A Darwish,Abdulrahman A Al-Majed,Nawaf A Alsaif et al.
Ibrahim A Darwish et al.
Darunavir: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl] (isobutyl)amino}-3-hydroxy-1-phenyl-2-butanyl]carbamate is a synthetic non-peptide protease inhibitor. On June 2006, it was first approved by the F...
Ahmed A Abdelgalil,Hamad M Al-Kahtani,Fahad I Al-Jenoobi
Ahmed A Abdelgalil
Erlotinib (OSI-774), marketed by Genentech as Tarceva®, is anticancer drug approved by US-FDA for the treatment of Non-Small Cell Lung Cancer (NSCLC) and Pancreatic Cancer. Erlotinib inhibited epidermal growth factor receptor (EGFR) that b...