Activation of peroxisome proliferator-activated receptor-α (PPARα) in proximal intestine improves postprandial lipidemia in obese diabetic KK-Ay mice [0.03%]
激活近端肠胰蛋白酶扩张子激活受体-α(PPARα)可改善肥胖糖尿病KK-Ay小鼠的餐后脂血症
Rino Kimura,Nobuyuki Takahashi,Tsuyoshi Goto et al.
Rino Kimura et al.
Postprandial lipidemia is a risk factor for cardiovascular diseases. Thus, the suppression of postprandial lipidemia is valuable for disease management. Peroxisome proliferator-activated receptor- (PPAR ) is a key regulator in the lipid met...
Effects of hydrophilic statins on renal tubular lipid accumulation in diet-induced obese mice [0.03%]
亲水性他汀类药物对高脂饮食诱导的肥胖小鼠肾小管腔内脂质积累的影响
Koro Gotoh,Takayuki Masaki,Seiichi Chiba et al.
Koro Gotoh et al.
Animal models of obesity show that lipid deposits can injure the kidneys,and there is evidence for the role of lipids in the development of chronic renal dis-ease (CKD). Statins exhibit a lipid-lowering effect that acts on both total choles...
Increased oxidative stress in obesity: implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer [0.03%]
肥胖引起的氧化应激增强及其对代谢综合征、糖尿病、高血压、脂质异常血症、动脉粥样硬化和癌症的影响
Morihiro Matsuda,Iichiro Shimomura
Morihiro Matsuda
Obesity, especially of the abdominal type, is a health problem that constitutes metabolic syndrome and increases the incidence of various diseases, including diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer. Various mechani...
The roles of salivary secretion, brain-gut peptides, and oral hygiene in obesity [0.03%]
唾液分泌、脑-肠肽和口腔卫生在肥胖症中的作用
Hirotaka Ueda,Takakazu Yagi,Haruka Amitani et al.
Hirotaka Ueda et al.
Obesity has a prevalence of 15-30% among European and American populations. It is an incurable chronic disease associated with considerable mortality and co-morbidity. The co-morbidity risk can be reduced substantially by a moderate weight ...
Masao Yamasaki,Teruyoshi Yanagita
Masao Yamasaki
Conjugated linoleic acid (CLA), which is a generic term to describe isomers of octadecadienoic acid, has been reported to exert various beneficial physiological effects. Accumulating data show that CLA, especially trans10, cis12 (t10, c12)-...
Validity of clinical body weight measures as substitutes for missing data in a randomized trial [0.03%]
临床体重测量数据在随机对照试验中替代缺失值的有效性研究
David Arterburn,Laura Ichikawa,Evette J Ludman et al.
David Arterburn et al.
Background: Long-term follow-up of weight loss interventions is essential, but collecting weights can be difficult, and self-reports inaccurate. We examined the relationship between weight measures obtained in the context...
Measurement of visceral fat by abdominal bioelectrical impedance analysis is beneficial in medical checkup [0.03%]
腹部生物电阻抗测量 visceral fat 有助于健康检查
Kentaro Shoji,Kazuhisa Maeda,Tadashi Nakamura et al.
Kentaro Shoji et al.
Objective: In addition to the waist circumference (WC) measurement, an accurate measurement of visceral fat is very important in terms of the pathology associated with the metabolic syndrome. The only method available for...
Should overweight and obese primary care patients be offered a meal replacement diet? [0.03%]
肥胖及体重超重的门诊病人需要被提供代餐饮食吗？
James E Rohrer,Paul Takahashi
James E Rohrer
Objectives: Randomized controlled pilot study of the impact of a 30-day meal replacement (MR) diet on body weight. Methods: Sixty-three...
Weight reduction improves sleep, sleepiness and metabolic status in obese sleep apnoea patients [0.03%]
体重减轻改善肥胖睡眠呼吸暂停患者的睡眠、嗜睡和代谢状况
Pia Nerfeldt,Bengt Y Nilsson,Liliana Mayor et al.
Pia Nerfeldt et al.
Method: In this prospective intervention study, 33 obese patients with obstructive sleep apnoea syndrome (OSAS) (24 men, 9 women) were consecutively enrolled for a weight reduction program at the Obesity Unit, Karolinska ...
Overweight and obesity in 4-year-old South Australian children and the stability of IOTF cut points in this age group [0.03%]
南澳大利亚4岁儿童的超重和肥胖及这一年龄段内IOTF切点的稳定性
Julie Franzon,Graeme Hugo,Gary Wittert et al.
Julie Franzon et al.
Objective: To assess the validity of internationally accepted mid-year cut points for overweight and obesity in children and their application for ongoing surveillance. ...