The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer [0.03%]
上皮间质转化（EMT）与甲状腺激素-αvβ3轴在卵巢癌中的相互作用
Chen Weingarten,Yonatan Jenudi,Rami Yair Tshuva et al.
Chen Weingarten et al.
Ovarian cancer is a highly metastatic disease. The metastatic potential is enhanced by epithelial to mesenchymal transition (EMT) in which αvβ3 integrin plays a role. Thyroid hormones (L-thyroxine, T4, and 3,5,3'-triiodo-L-thyronine, T3) ...
BRAF-Oncogene-Induced Senescence and the Role of Thyroid-Stimulating Hormone Signaling in the Progression of Papillary Thyroid Carcinoma [0.03%]
BRAF原癌基因诱导的衰老及促甲状腺激素信号在乳头状甲状腺癌进展中的作用
F I Moulana,A A H Priyani,M V C de Silva et al.
F I Moulana et al.
Oncogene-induced senescence (OIS) explains the phenomenon of cellular senescence triggered by the action of oncogenes. It is a mechanism adopted by a cell to inhibit progression of benign tumors into malignancy, occurs in premalignant lesio...
Time Until Partial Response in Metastatic Adrenocortical Carcinoma Long-Term Survivors [0.03%]
长期生存的转移性肾上腺皮质癌患者的部分缓解时间
Delphine Vezzosi,Christine Do Cao,Ségolène Hescot et al.
Delphine Vezzosi et al.
A partial response (PR) has been proposed as a surrogate for overall survival in advanced adrenocortical carcinoma (ACC). The primary endpoint of the study was to characterize the time until a PR in patients with metastatic ACC treated with...
Amanda Leiter,Nina A Bickell,Derek LeRoith et al.
Amanda Leiter et al.
Studies show decreased risk of breast cancer recurrence and improved survival with statin use, but data on racial disparities regarding breast cancer prognosis and statin use are lacking. Our objective was to investigate if racial dispariti...
Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells [0.03%]
胃细胞肿瘤组织中胆囊收缩素-苯丙氨酸1-13(B型)受体的表达
Patricia Mjønes,Ivar S Nordrum,Øystein Sørdal et al.
Patricia Mjønes et al.
Gastric cancer is an important disease due to its high mortality. Despite the decline in frequency, most cases are discovered late in its course, and most of the cancer patients die within a few years of diagnosis. In addition to Helicobact...
Expression of Genes for Methylxanthine Pathway-Associated Enzymes Accompanied by Sex Steroid Receptor Status Impacts Breast Carcinoma Progression [0.03%]
甲基黄嘌呤代谢相关基因的表达伴随性激素受体状态影响乳腺癌进程
James L Wittliff,Seth B Sereff,Michael W Daniels
James L Wittliff
Consumption of methylxanthine alkaloids appears to induce activities by antagonizing adenosine receptors, implicated in breast cancer behavior in vitro. Our goal was to evaluate expression of genes for methylxanthine receptors and metaboliz...
O-GlcNAc-Dependent Regulation of Progesterone Receptor Function in Breast Cancer [0.03%]
O-GlcNAc对乳腺癌中孕激素受体功能的调节作用
Gloria M Trinca,Merit L Goodman,Evangelia K Papachristou et al.
Gloria M Trinca et al.
Emerging clinical trial data implicate progestins in the development of breast cancer. While the role for the progesterone receptor (PR) in this process remains controversial, it is clear that PR, a steroid-activated nuclear receptor, alter...
Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer [0.03%]
生长激素释放素(GHRH)拮抗剂在甲状腺癌中的抑制作用
Helena Pópulo,Bruno Nunes,Cristina Sampaio et al.
Helena Pópulo et al.
Growth hormone-releasing hormone (GHRH) is a peptide hormone secreted by the hypothalamus that regulates the synthesis and secretion of growth hormone (GH) in the pituitary. The extra-hypothalamic GHRH and its cognate receptors (GHRHR and s...
Parity and Risk of Thyroid Cancer: a Population-Based Study in Lithuania [0.03%]
立陶宛一项基于人口的关于甲状腺癌发病风险性别差异的研究
L Zabuliene,D Jasilionis,E Miseikyte-Kaubriene et al.
L Zabuliene et al.
An association between parity and thyroid cancer risk has been investigated in a number of independent studies but yielded contradictory findings. The aim of this study was to explore the association between parity and thyroid cancer risk. ...
Maternal Resveratrol Treatment Reduces the Risk of Mammary Carcinogenesis in Female Offspring Prenatally Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin [0.03%]
母体白藜芦醇治疗可降低孕期接触二噁英的雌性后代患乳腺癌的风险
Tássia C de Lima E Silva,Livia T R da Silveira,Mariana F Fragoso et al.
Tássia C de Lima E Silva et al.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) presents adverse effects on breast development/carcinogenesis. This study aimed to identify the ability of resveratrol (Res) to modify the adverse effects of TCDD in a female offspring. Pregnant fe...