Lower Circulating Androgens Are Associated with Overall Cancer Risk and Prostate Cancer Risk in Men Aged 25-84 Years from the Busselton Health Study [0.03%]
贝塞尔顿健康研究中男性总癌症风险和前列腺癌风险与循环雄激素水平较低有关(25-84岁)
Yi X Chan,Matthew W Knuiman,Mark L Divitini et al.
Yi X Chan et al.
Androgens, notably testosterone (T), have been implicated in development of several common cancers and prostate cancer; however, precise mechanisms remain unclear. This study assessed prospective associations of serum T, dihydrotestosterone...
Konstantinos Segkos,Kyle Porter,Leigha Senter et al.
Konstantinos Segkos et al.
There are limited data on the role of neck ultrasound (US) in the surveillance of patients with follicular thyroid cancer (FTC). Here, we analyze the likelihood of US to find structural disease in patients with FTC and evaluate if initial A...
Mammographic Density and Circulating Sex Hormones: a Cross-Sectional Study in Postmenopausal Korean Women [0.03%]
绝经后韩国女性乳腺密度与循环性激素的横断面研究
Kayoung Lee,Jung Eun Yoo,Tuong Linh Nguyen et al.
Kayoung Lee et al.
Mammographic density (MD) is a strong independent risk factor for breast cancer. It has been suggested that breast cancer is related to the exposure to circulating sex hormones. However, relations between MD and hormones have been inconsist...
Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers [0.03%]
纳米二胺四碳(NDAT)通过作用于RRM2通路增强白藜芦醇在结直肠癌中的抗增殖效果
André Wendindondé Nana,Szu Yuan Wu,Yu-Chen Sh Yang et al.
André Wendindondé Nana et al.
Cancer resistance to chemotherapeutic agents is a major issue in the management of cancer patients. Overexpression of the ribonucleotide reductase regulatory subunit M2 (RRM2) has been associated with aggressive cancer behavior and chemores...
Impact of Gender and Age on the Prognosis of Differentiated Thyroid Carcinoma: a Retrospective Analysis Based on SEER [0.03%]
性别和年龄对分化型甲状腺癌预后影响的回顾性分析基于SEER数据库
Dan Zhang,Jianing Tang,Deguang Kong et al.
Dan Zhang et al.
The incidence of thyroid cancer in females is significantly higher than that in males; however, females are more likely to have more favorable outcomes. We aimed to determine the characteristics of differentiated thyroid carcinoma (DTC) sub...
RAGE and Its Ligands: Molecular Interplay Between Glycation, Inflammation, and Hallmarks of Cancer-a Review [0.03%]
Rage及其配体:糖基化、炎症和癌症标志物之间的分子相互作用-综述文章
Gowri Palanissami,Solomon F D Paul
Gowri Palanissami
Risk of cancer especially of colon, breast, and pancreas is high in diabetic and obese patients, with potential involvement of augmented expression of RAGE (receptor for advanced glycation end products) and its ligands, namely AGEs (advance...
Increased High Molecular Weight FGF2 in Endocrine-Resistant Breast Cancer [0.03%]
内分泌难治性乳腺癌中高分子量FGF2水平升高
Ana Sahores,Virginia Figueroa,María May et al.
Ana Sahores et al.
Endocrine resistance may develop as a consequence of enhanced growth factor signaling. Fibroblast growth factor 2 (FGF2) consists of a low and several high molecular weight forms (HMW-FGF2). We previously demonstrated that antiprogestin-res...
RNA Sequencing of Carboplatin- and Paclitaxel-Resistant Endometrial Cancer Cells Reveals New Stratification Markers and Molecular Targets for Cancer Treatment [0.03%]
卡铂和紫杉醇耐药性子宫内膜癌细胞的RNA测序发现了新的分层标志物及癌症治疗分子靶点
Raffaele Hellweg,Ashley Mooneyham,Zenas Chang et al.
Raffaele Hellweg et al.
Despite advances in surgical technique and adjuvant treatment, endometrial cancer has recently seen an increase in incidence and mortality in the USA. The majority of endometrial cancers can be cured by surgery alone or in combination with ...
The Influence of Menopausal Hormone Therapy and Potential Lifestyle Interactions in Female Cancer Development-a Population-Based Prospective Study [0.03%]
关于激素替代疗法及潜在生活方式对女性癌症发病影响的基于人群的前瞻性研究
Marianne Holm,Anja Olsen,Cecilie Kyrø et al.
Marianne Holm et al.
The past decades have seen contradictory research results on the health benefits and risks of menopausal hormone therapy (HT). In particular, long-term associations with overall cancer incidence and the potential interplay with other lifest...
Risk Analysis of Prostate Cancer Treatments in Promoting Metabolic Syndrome Development and the Influence of Increased Metabolic Syndrome on Prostate Cancer Therapeutic Outcome [0.03%]
前列腺癌治疗促进代谢综合征发展的风险分析及代谢综合征增加对前列腺癌治疗结局的影响
Zongping Chen,Jichun Deng,Yong Yan et al.
Zongping Chen et al.
In clinical practice, few prostate cancer (PCa) patients are associated with metabolic syndrome (MetS), while few others acquire MetS during treatment. Whether the treatment of PCa increases the occurrence of MetS remains to be confirmed. T...